CAS: 186028-80-8; 1-(1,3-Benzodioxol-5-yl)-2-(Methylamino)Propan-1-One,Hydrochloride

📜亚甲基二氧基甲卡西酮置于盐酸体系中,用 乙醚 用作溶剂,以94 %的收率获得2-甲基氨基-1-(3,4-亚甲二氧苯基)-1-丙酮盐酸盐
参考文献: Isotopologes,Salts,Crystalline Forms,Stereoisomers,Of Methylone And Ethylone And Methods Of Use Thereof[fr] Isotopologues,Sels,Formes Cristallines,Stéréoisomères,De Méthylone Et D'éthylone Et Leurs Procédés D'Utilisation
标题: Isotopologes,Salts,Crystalline Forms,Stereoisomers,Of Methylone And Ethylone And Methods Of Use Thereof[fr] Isotopologues,Sels,Formes Cristallines,Stéréoisomères,De Méthylone Et D'éthylone Et Leurs Procédés D'Utilisation
摘要:Described Herein Are Isotopically Enriched Analogs Of Methylone (E.G.,Deuterated Analogs Of Methylone (E.G.,(S)-Methylone And (R)-Methylone) With Improved Characteristics. Also Described Herein Are Salts (Such As Hydrochloride Salt) And Solid Forms (E.G.,Crystalline Forms) Of Methylone. Also Described Herein Are Stereoisomers (E.G.,Enantiomers) Of Methylone. The Present Disclosure Also Provides Methods Of Making And Methods Of Use Of The Methylone Or Methylone Analogs And Solid Forms Of 3,4-Methylenedioxy-N-Ethylcathinone Hydrochloride Described Herein To Treat Brain And Neurological Disorders Such As Depression.

专利信息

专利号:US-2024374558-A1
优先权日:2022-10-20
标题 :Preparation of phenethylamines and cathinones and stereoisomers thereof and precursors thereof
发明人：SCHMIDT JENNIFER LOUISE; STOGNIEW MARTIN
权利人:TRANSCEND THERAPEUTICS INC
摘要:In one aspect, the present disclosure provides a method of synthesis for methylone HCl, with 3,4-methylenedioxypropiophenone (MDP) as the starting material. In another aspect, the present disclosure provides stereoisomers of methylone. In another aspect, the present disclosure provides phenethylamines or cathinones covalently bound to a chemical moiety in a prodrug form. The presently described prodrug form allows slow/sustained/controlled delivery of the parent phenethylamines or cathinones into the blood system in a manner that would increase the duration of therapeutic efficacy.

专利号:CN-118122367-A
优先权日:2022-12-02
标 题:A supported noble metal catalyst and its preparation method and its application in the gas phase synthesis of dimethyl carbonate and co-production of methyl formate

专利号:CN-113603640-A
优先权日:2021-08-06
标题 :Synthesis method of pirenone ethylamine salt