CAS: 159766-56-0; Fmoc-Lys(Ac)-Oh

相似化合物

320410-22-8 10009-20-8 76265-69-5

上下游产品

CAS号71989-26-9 Nα-芴甲氧羰基-Nε-叔丁氧...

(2S)-6-(2-Carboxyacetamido)-2-({[(9H-Fluoren-9-yl)Methoxy]Carbonyl}Amino)Hexanoic Acid 以 Aq. Phosphate Buffer 用作溶剂,化学反应 6.0H,反应生成Fmoc-N'-乙酰基-L-赖氨酸
参考文献:丙二酰赖氨酸稳定等排物的合成与评价**
标题:丙二酰赖氨酸稳定等排物的合成与评价**
摘要:赖氨酸丙二酰化的热诱导脱羧特性可能对其研究提出潜在挑战.我们的研究表明,丙二酰四唑修饰的赖氨酸作为丙二酰赖氨酸的稳定生物电子等排物表现出色,可以应对此类挑战.酶学数据还证实,丙二酰和丙二酰四唑具有相似的受体识别分子相互作用表面.
Doi:10.1002/cbic.202100491

专利信息

专利号:US-2024218014-A1
优先权日:2022-11-21
标 题:Synthesis of a cyclic peptide
发明人：BAUR PIUS BRUNO; CLEATOR EDWARD; DENIAU GILDAS; EISELE FRANK; FLÖGEL OLIVER; HUSTE ANJA; KEHL MARCEL ROMAN; LÖWENECK MARKUS; SILVA ROLANDO RAVELO; VORBERG RAFFAEL
权利人:JANSSEN PHARMACEUTICA NV
摘要:Processes for performing peptide synthesis, particularly for cyclic peptide synthesis are generally described. Reaction intermediates of the peptide synthesis are also described.

专利号:EP-4622991-A2
优先权日:2022-11-21
标 题:Synthesis of a cyclic peptide

专利号:US-8338565-B2
优先权日:2008-08-20
标 题 :Macrocyclic compounds for inhibition of tumor necrosis factor alpha
发明人：LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P
权利人:LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P; ENSEMBLE THERAPEUTICS CORP
摘要:Disclosed herein are macrocyclic compounds and methods for their synthesis and use. In particular, macrocyclic compounds are disclosed that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.

专利号:WO-2024110477-A2
优先权日:2022-11-21
标 题:Synthesis of a cyclic peptide

专利号:US-10501496-B2
优先权日:2013-05-23
标 题 :Chemical synthesis and screening of bicyclic peptide libraries