专利号:US-7754646-B2 优先权日:2001-06-29 标 题 :Synthesis and use of organosilica particles 发明人:TRAU MATHIAS; JOHNSTON ANGUS 权利人:NANOMICS BIOSYSTEMS PTY LTD 摘要:Highly functionalized, porous organosilica particles and methods of their synthesis are described that employ high amounts of functional silane such as 3-mercaptopropyl trimethoxysilane. Silane particle diameters are controlled from less than 1 μm to over 100 μm. The particles have a high surface area due to their advantageous internal structures, which consist of large pores, typically up to 10 μm that are linked by small channels of typically about 20 nm diameter. Isothiocyanate modified fluorescent dyes can enter and react with thiol groups inside the pores. The invention also provides clear silica shells of controlled thicknesses to protect fluorescent signals and provide an independent parameter for distinguishing particle types based on light scattering off different sized particles. The particles are stable and useful for many purposes, particularly for optical bar coding in combinatorial synthesis of polymers such as nucleic acid, polypeptide, and other synthesized molecules.
专利号:US-2019016909-A1 优先权日:2016-01-11 标题:Template synthesis of polymeric nanomaterials by ink-jet printing 发明人:PHILLIP WILLIAM A; QU SIYI; BENAVIDES SHERWOOD; GAO PENG; GAO FENG 权利人:UNIV NOTRE DAME DU LAC 摘要:A method for fabricating nanostructured polymeric materials based on a combination of inkjet printing and template synthesis. Layer-by-layer assembled nanotubes can be synthesized in a polycarbonate track-etched (PCTE) membrane by printing poly(allylamine hydrochloride) (PAH) and poly(styrenesulfonate) (PSS) sequentially. By changing the printing conditions, polymeric nanotubes or nanowires can be prepared by printing poly(vinyl alcohol) (PVA) in a PCTE template. Inkjet printing paired with template synthesis can be used to generate patterns comprised of chemically distinct nanomaterials. Thin polymeric films of layer-by-layer assembled PAH and PSS can be printed on a PCTE membrane. Inkjet printing paired with template synthesis can also be used to prepare functional mosaic membranes, such as charge mosaic membranes comprising polyelectrolytes of different charges to pattern positively charged or negatively-charged domains, respectively, on the surface of the template.
专利号:US-2024051897-A1 优先权日:2022-07-26 标题:Synthesis of complex 15n-labeled molecules 发明人:DORSHEIMER JULIA; ROVIS TOMISLAV 权利人:UNIV COLUMBIA 摘要:Methods for conversion of a broad range of amines to their 15N isotopic counterparts and the compounds produced thereby.
专利号:US-10245558-B2 优先权日:2011-09-09 标 题 :Green synthesis nanocomposite membranes 发明人:BHATTACHARYYA DIBAKAR; SMULEAC VASILE; VARMA RAJENDER S; SIKDAR SUBHAS K 权利人:THE UNIV OF KENTUCKY RESEARCH FOUNDATION; US ENVIRONMENT 摘要:A nanocomposite membrane includes a macroporous polymer membrane having a plurality of pores. A plurality of metal nanoparticles are synthesized and immobilized within those plurality of pores. The nanoparticles are reduced and capped with a green reducing and capping agent such as green tea extract.
专利号:US-2013211542-A1 优先权日:2012-02-08 标题:Synthesis of nanotopographic biomimetic membranes for tissue culture, engineering and prosthetics applications 发明人:MCKEE CLAYTON; MURPHY CHRISTOPHER J; RUSSELL PAUL; GARLAND SHAUN P 权利人:UNIV CALIFORNIA; UNIV CALIFORNIA 摘要:The present invention provide methods for preparing nanostructured membranes. The methods include: providing a substrate with a charged silanized surface; forming a multilayered membrane containing at least two polyelectrolytes; inducing polyelectrolyte phase separation; crosslinking the multilayered membrane; and covalently linking the multilayered membrane to the silanized surface. Methods for fabricating membrane replicas are also disclosed, as well as devices such as cell- and tissue-culture substrates that contain the membranes and membrane replicas. Resulting materials exhibit topographic features and compliance of the extracellular matrix in vivo.
专利号:WO-2013113319-A1 优先权日:2012-01-31 标题 :Process for the preparation of strontium ranelate, intermediate or hydrates thereof 发明人:KOFTIS THEOCHARIS V; ROHIT RAVIKANT SONI; BHARAT BECHARBHAI BODA; DIPAKKUMAR NARSIBHAI BHUT; VIMALKUMAR SUBHIRBHAI PATEL 权利人:PHARMATHEN SA; KOFTIS THEOCHARIS V; ROHIT RAVIKANT SONI; BHARAT BECHARBHAI BODA; DIPAKKUMAR NARSIBHAI BHUT; VIMALKUMAR SUBHIRBHAI PATEL 摘要:The present invention relates to an improved process for the synthesis of strontium ranelate compound of formula I or its hydrates thereof. More particularly, the present invention relates to an economically viable and industrially feasible process for the preparation of strontium ranelate, intermediate or its hydrates thereof.
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合成参考文献
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