CAS: 75400-67-8; 1-Boc-Indole

上下游产品

N-叔丁氧羰基-5-溴吲哚 5-Bromo-Indole-1-Carboxylic Acid Tert-Butyl Ester 182344-70-3
1-Boc-3-碘吲哚 Tert-Butyl 3-Iodo-1H-Indol-1-Carboxylate 192189-07-4
1-(Pivaloyloxymethyl)Indole 108940-04-1
1-羟甲基-1H-吲哚 (1H-Indol-1-yl)Methanol 08/11/5031
1-Boc-吲哚-2-硼酸 N-Boc-Indole-2-Boronic Acid 213318-44-6

2-氨基苯乙醇置于二(氰基苯)二氯化钯,亚硝酸特丁酯,氧气,三乙胺,Potassium Hydroxide体系中,用 二氯甲烷,叔丁醇 作为反应溶剂,180.0 °C,101.33 Kpa 条件下,反应 18.0H,反应生成 1-Boc-吲哚
参考文献:Pd-Tbuono共催化好氧吲哚合成
标题:Pd-Tbuono共催化好氧吲哚合成
摘要:甲的pd-吨作为终端氧化剂被显影buono共催化的分子氧吲哚的可扩展性和实用的合成.在一种通用条件下,末端或内部2乙烯基苯胺均可顺利转化为所需的吲哚.吲哚美辛和潜在的抗乳腺癌候选药物1的大规模合成已对该方法进行了评估.
DOI:10.1002/adsc.201701512

专利信息

专利号:US-2012328569-A1
优先权日:2010-03-02
标题:Inhibitors of hepatitis c virus ns5b polymerase
发明人：MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO; NARJES FRANK; HABERMANN JOERG; KOCH UWE; LIU SHILAN
权利人:MCCOMAS CASEY CAMERON; LIVERTON NIGEL J; SOLL RICHARD; LI PENG; PENG XUANJIA; WU HAO; NARJES FRANK; HABERMANN JOERG; KOCH UWE; LIU SHILAN
摘要:Disclosed are compounds of formula (I) that are used as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

专利号:CN-117597329-A
优先权日:2021-05-05
标题:Method for the catalytic synthesis of tryptamine and precursors thereof

专利号:US-2015315143-A1
优先权日:2014-05-01
标题 :N-Heterocyclic Carbene-Catalyzed Synthesis of 2-Aryl Indoles

专利号:CN-109748841-B
优先权日:2019-01-08
标 题:Method for catalyzing asymmetric synthesis of chiral beta-aminoketone derivative

专利号:US-9527812-B2
优先权日:2014-05-01
标题 :N-heterocyclic carbene-catalyzed synthesis of 2-aryl indoles
发明人：SCHEIDT KARL A; HOVEY JR MICHAEL TODD; CHECK CHRISTOPHER
权利人:UNIV NORTHWESTERN
摘要:Transition metal-free catalytic methods for access to 2-arylindole compounds.

专利号:US-2008139558-A1
优先权日:2006-02-24
标题 :Quinolones useful as inducible nitric oxide synthase inhibitors
发明人：SMITH NICHOLAS D; ROPPE JEFFREY R; BONNEFOUS CELINE; PAYNE JOSEPH E; ZHUANG HUI; CHEN XIAOHONG; LINDSTROM ANDREW K; DURON SERGIO G; HASSIG CHRISTIAN A; NOBLE STEWART A
权利人:KALYPSYS INC
摘要:The present invention relates to novel quinolones of Formula I that inhibit inducible NOS synthase together with methods of synthesizing and using the compounds including methods for inhibiting or modulating nitric oxide synthesis and/or lowering nitric oxide levels in a patient by administering the compounds for the treatment of disease.