CAS: 72716-87-1; 2-Methoxyisonicotinaldehyde

相似化合物

123148-66-3 72716-86-0 764708-19-2

上下游产品

CAS号72716-86-0 4-氰基-2-甲氧基砒啶 | CAS号563-41-7 盐酸氨基脲 | CAS号123148-66-3 2-甲氧基吡啶-4-甲醇 | CAS号33252-30-1 2-氯-4-氰基吡啶 | CAS号26156-51-4 2-甲氧基异烟酸甲酯 | CAS号92838-85-2 ethyl 3-(2-meth...

2-甲氧基异烟酸甲酯置于lithium Aluminium Tetrahydride,三氧化硫吡啶,三乙胺体系中,用 四氢呋喃,乙醚,水,二甲基亚砜 作为反应溶剂,化学反应 0.83H,反应生成 2-甲氧基吡啶-4-醛
参考文献:Ep2816032
标题:Ep2816032

专利信息

专利号:US-12319691-B2
优先权日:2020-05-04
标题 :Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：CZABANIUK LARA C; HOPPER TIMOTHY; HOUZE JONATHAN B; RESCOURIO GWENAELLA; SANTORA VINCENT; WANG HAOXUAN; WHITE RYAN D; WONG ALICE R; WU YONGWEI
权利人:AMGEN INC; VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2â€?).This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.

专利号:US-12428425-B2
优先权日:2020-05-04
标 题:Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use
发明人：CZABANIUK LARA C; HOPPER TIMOTHY; HOUZE JONATHAN B; PANTELEEV JANE; RESCOURIO GWENAELLA; SANTORA VINCENT; WANG HAOXUAN; WHITE RYAN D; WONG ALICE R; WU YONGWEI; BOS MAXENCE; MANCUSO JOHN; FRANZONI IVAN
权利人:AMGEN INC; VIGIL NEUROSCIENCE INC
摘要:The present disclosure provides compounds of Formula I, useful for the activation of Triggering Receptor Expressed on Myeloid Cells 2 (“TREM2â€?).This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, a neurodegenerative disorder. Further, the disclosure provides intermediates useful in the synthesis of compounds of Formula I.