CAS: 71980-98-8; 9-(((E)-4-((2S,3R,4R,5S)-3,4-Dihydroxy-5-((4R,5S,E)-5-Hydroxy-4-Methylhex-2-En-1-yl)Tetrahydro-2H-Pyran-2-yl)-3-Methylbut-2-Enoyl)Oxy)Nonanoic Acid
该化合物是一个复杂的有机化合物,其特点是其复杂的分子结构,包括多种功能组,如碳箱酸,氢氧化物组和藻类.这种化合物具有长碳链,有助于其疏水分特性,而极地功能组的存在则增强了其在极地溶剂中的溶性.2E,4R,5S)的注解表明,原子的具体空间安排可以极大地影响化合物的再活性和生物活动.这些化合物由于其独特的结构特性,常常被研究其可能应用于医药,生物化学,生物化学和材料科学.由于其独特的结构特性,水糖感学的存在表明它有可能与生物系统发生相互作用,从而使其在化学的化合物中产生其复杂性.
- 英文名称9-(((E)-4-((2S,3R,4R,5S)-3,4-Dihydroxy-5-((4R,5S,E)-5-Hydroxy-4-Methylhex-2-En-1-yl)Tetrahydro-2H-Pyran-2-yl)-3-Methylbut-2-Enoyl)Oxy)Nonanoic Acid
- 中文名称伪单胞菌酸C
- IUPAC名称9-(((E)-4-((2S,3R,4R,5S)-3,4-dihydroxy-5-((4R,5S,E)-5-hydroxy-4-methylhex-2-en-1-yl)tetrahydro-2H-pyran-2-yl)-3-methylbut-2-enoyl)oxy)nonanoic acid
- 其它别名9-[[(2E)-4-[[(2S,3R,4R,5S)-3α,4α-Dihydroxy-5β-[(2E,4S,5S)-5-Hydroxy-4-Methyl-2-Hexenyl]Tetrahydro-2H-Pyran]-2β-Yl]-3-Methyl-2-Butenoyl]Oxy]Nonanoic Acid; Mupirocin Calcium Impurity 2(Mupirocin Calcium Ep Impurity B); Mupirocin Calcium Ep Impurity B; Mupirocin Ep Impurity B/pseudomonic Acid C/9-[[(2E)-4-[(2S,3R,4R,5S)-3,4-Dihydroxy-5-[(2E,4R,5S)-5-Hydroxy-4-Methylhex-2-Enyl]Tetrahydro-2H-Pyran-2-Yl]-3-Methylbut-2-Enoyl]Oxy]Nonanoic Acid; 9-[(E)-4-[(2S,3R,4R,5S)-3,4-Dihydroxy-5-[(E,4R,5S)-5-Hydroxy-4-Methylhex-2-Enyl]Oxan-2-Yl]-3-Methylbut-2-Enoyl]Oxynonanoic Acid; L-Talo-Non-2-Enonic Acid, 5,9-Anhydro-2,3,4,8-Tetradeoxy-8-[(2E,4R,5S)-5-Hydroxy-4-Methyl-2-Hexen-1-Yl]-3-Methyl-, 8-Carboxyoctyl Ester, (2E)-; 9-(((E)-4-((2S,3R,4R,5S)-3,4-Dihydroxy-5-((4R,5S,E)-5-Hydroxy-4-Methylhex-2-En-1-yl)Tetrahydro-2H-Pyran-2-yl)-3-Methylbut-2-Enoyl)Oxy)Nonanoic Acid; Mupirocin Caclium Impurity B
- CAS编号71980-98-8
- MFCD编号:MFCD35200217
- FDA UNII编号:O6M926DF2R
- 分子式:C26H44O8分子量:484.62
- 产品CID: 2533340
- 产品分类分析化学 → 标准品 → 药典标准品和杂质标准品
- 相似结构搜索
- InChIKey: KKMHFUKZHJOMJL-WZLBZGCNSA-N
- KKMHFUKZHJOMJL-QEPDBURXNA-N
- 计算化学: 氢键受体数8.0氢键供体数4.0可旋转键数17.0
物理性质
MSDS等安全信息
上下游产品
Ethyl monate C *,5R*)>>-9--2-butenyl>oxy>nonanoic acid methyl ester2S-2α(E),3β,4β,5α(2E,4S*,5R*)-9-3-methyl-1-oxo-4--2-butenyloxynonanoic acid methyl ester 9-{(E)-4-[(2S,3S,4R,5S)-3,4-Bis-benzyloxy-5-((E)-(4R,5S)-5-benzyloxymethoxy-4-methyl-hex-2-enyl)-tetrahydro-pyran-2-yl]-3-methyl-but-2-enoyloxy}-nonanoic acid methyl ester methyl 9-hydroxynonanoate合成工艺路线路线简述
📜L-Lyxose置于吡啶,过氧乙酸,氢氧化钾,Sodium Tetrahydroborate,Sodium Periodate,四氧化锇,氨,甲基锂,Lithium,碳酸氢钠,Sodium Carbonate,Potassium Carbonate,对甲苯磺酸,溶剂黄146,Lithium Hexamethyldisilazane,Lithium Diisopropyl Amide体系中,用 四氢呋喃,乙醇,二氯甲烷,N,N-二甲基甲酰胺,丙酮,甲苯 作为反应溶剂,化学反应 27.25H,反应生成 伪单胞菌酸c
参考文献:Total Synthesis Of Pseudomonic Acid C
标题:Total Synthesis Of Pseudomonic Acid C
摘要:
DOI:10.1021/jo00182A037
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905122000-异丙醇
2905310000-1,2-乙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
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主要参考文献
1: Sridhar Y, Srihari P. A unified strategy for the synthesis of the C1-C14 fragment of marinolic acids, mupirocins, pseudomonic acids and thiomarinols: total synthesis of pseudomonic acid methyl monate C. Org Biomol Chem. 2014 May 14;12(18):2950-9. doi: 10.1039/c4ob00025k. doi: 10.1016/j.syapm.2008.11.001. Epub 2008 Dec 12. Epub 2007 Mar 23.
6: Rechsteiner T, Leisinger T. Purification of isoleucyl-tRNA synthetase from Methanobacterium thermoautotrophicum by pseudomonic acid affinity chromatography. Eur J Biochem. 1989 Apr 15;181(1):41-6. doi: 10.1021/ja501731p. Epub 2014 Mar 27. doi: 10.1007/s15010-013-0581-1. Epub 2014 Jan 25. doi: 10.1186/s12866-014-0212-8.
10: Hartman-Adams H, Banvard C, Juckett G. Impetigo: diagnosis and treatment. Am Fam Physician. 2014 Aug 15;90(4):229-35. Review. doi: 10.1016/j.resmic.2014.09.009. Epub 2014 Oct 7. doi: 10.1038/srep11596.
合成参考文献
参考文献:10.5281/zenodo.5794106
摘要:The LOTUS Initiative for Open Natural Products Research: frozen dataset union wikidata (with metadata) | DOI:10.5281/zenodo.5794106
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