CAS: 3588-60-1; Z-Dl-Leu-Oh

上下游产品

benzyl-8-quinolyl carbonate LEUCINE 3,5-dimethyl-pyrazole-1-carboxylic acid benzyl ester benzyl chloroformateD(L)-Z-Leu-PNP N-benzyloxycarbonyl-leucyl)-phosphoric acid dibenzyl ester(N-benzyloxycarbonyl-leucyl)-phosphoric acid dibenzyl ester N-benzyloxycarbonyl-DL-thioleucine S-(4-nitro-phenyl ester)N-benzyloxycarbonyl-DL-thioleucine S-(4-nitro-phenyl ester) 4-(2-methylpropyl)oxazolidine-2,5-dione

Methyl ((Benzyloxy)Carbonyl)Leucinate置于sodium Hydroxide,水体系中,化学反应 16.0H,以91%的收率获得产物n-苄氧羰基-Dl-亮氨酸
参考文献:New Synthetic Routes To α-Amino Acids And γ-Oxygenated α-Amino Acids. Reductive Denitration And Oxidative Transformations Of γ-Nitro-α-Amino Acids
标题:New Synthetic Routes To α-Amino Acids And γ-Oxygenated α-Amino Acids. Reductive Denitration And Oxidative Transformations Of γ-Nitro-α-Amino Acids
摘要:通过还原去硝化,γ-硝基-α-氨基酸衍生物可以转化为α-氨基酸;通过对应氨基酸酯硝酸盐衍生物的臭氧解聚,可以转化为γ-氧-α-氨基酸;而通过随后的氧功能团还原,可以转化为γ-羟基-α-氨基酸衍生物,这些转化反应均能获得较高的产率.由于γ-硝基-α-氨基酸衍生物是从n,O保护的脱氢丙氨酸制备而成,而后者又是通过特定途径从相应的丙氨酸,丝氨酸和半胱氨酸衍生物得到的,因此整体程序提供了一种选择性将这些简单的α-氨基酸转化为更复杂的氨基酸的方法.
DOI:10.1039/a707067E