专利号:WO-2024130393-A1 优先权日:2022-12-21 标 题 :Nanoparticle and method of synthesis thereof 发明人:MOSKOVCHENKO SVITLANA 权利人:MOSKOVCHENKO SVITLANA 摘要:The present technology relates to nanoparticles, compositions comprising said nanoparticles, and methods of synthesis of said nanoparticles; wherein the nanoparticles comprise a metal nanoparticle core, a first coating of amphiphilic molecules, and a second coating of essential oil, essential oil primary constituent, or both, which combine the antimicrobial properties of metal nanoparticles, amphiphilic molecules, and essential oil or essential oil primary constituents.
专利号:WO-2008053960-A1 优先权日:2006-11-02 标题:Ceramide synthesis accelerators, cosmetic preparation, skin preparation for external use, method of preventing aging, and method of diminishing wrinkle 发明人:IMAMURA KAZUYUKI; MACHIDA SHIGERU 权利人:MERCIAN CORP; IMAMURA KAZUYUKI; MACHIDA SHIGERU 摘要:A ceramide synthesis accelerator containing the sap of grapevines as an active ingredient; a ceramide synthesis accelerator containing the sap of grapevines and serine as active ingredients; a cosmetic preparation and a skin preparation for external use which each contains either of these ceramide synthesis accelerators; and a method of using these. Thus, a means of safely and effectively improving the barrier function of the skin is provided.
专利号:WO-2017033119-A1 优先权日:2015-08-25 标题 :Compositions and methods for the treatment of liver metabolic diseases 发明人:RAO M SURYA 权利人:RAO M SURYA 摘要:The invention relates to the compositions of formula I and formula II or its pharmaceutical acceptable polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprises a salt of bile acid and the methods for treating or preventing liver diseases, fatty liver, NASH, bile acid synthesis disorders due to single enzyme defects, gallstones, peroxisomal disorders may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of NASH, fatty liver, liver cirrhosis and Bile acid synthesis disorders due to single enzyme defects, gallstones and peroxisomal disorders.
专利号:US-2004220137-A1 优先权日:2001-07-07 标 题:Cosmetic and dermatological preparations containing osmolytes for the treatment of and active prevention of dry skin and of other negative alterations in the physiological homeostasis of healthy skin 发明人:SAUERMANN GERHARD 摘要:Use of n a) one or more compounds from the group of osmolytes or precursors and derivatives thereof, n b) optionally one or more compounds from the group of electrolytes and n c) optionally one or more compounds from the group formed by polyols and urea, n in preparations (cosmetics, dermatological preparations) to be applied topically for the treatment and active prevention of dry skin and for strengthening the barrier function of the skin, and for the treatment, care and prophylaxis of sensitive skin and/or for the treatment and prophylaxis of the symptoms of a negative change in the physiological homeostasis of healthy skin, in particular deficient, sensitive or hypoactive skin conditions or n deficient, sensitive or hypoactive conditions of skin appendages, inflamed skin conditions, and of atopic eczema, polymorphous photodermatosis, psoriasis, vitiligo, n sensitive, itching or irritated skin, n changes in normal lipid peroxidation, n a change in the ceramide, lipid and energy metabolism of healthy skin, n a change in the physiological transepidermal water loss, n a reduction in skin hydration and decrease in the moisture content of the skin, n change in the natural moisturizing factor content, n reduction in cell-cell communication, n deficiency symptoms of intracellular DNA synthesis, n DNA damage and reduction in endogenous DNA repair mechanisms, n activation of metalloproteinases and/or other proteases or inhibition of the corresponding endogenous DNA repair mechanisms, n deviations from the normal post-translational modifications of connective tissue constituents, n changes in the normal hyaluronic acid and glucosaminoglycan content of healthy skin, dandruff formation by the hair, flaking of the scalp and skin ageing.
专利号:BR-112020009361-A2 优先权日:2017-11-17 标 题 :compound of formula i, pharmaceutical composition to treat an eye disorder or complications thereof, method of synthesis of compound, method of treating an eye disorder or complications thereof in an individual who needs it and use of a compound
专利号:US-2021171564-A1 优先权日:2018-08-03 标 题 :Compositions and methods for the treatment of cancer 发明人:KANDULA MAHESH 权利人:CELLIX BIO PRIVATE LTD; CELLIX BIO PROVATE LTD 摘要:The compositions and compounds of formula I and formula II which includes nucleic acid synthesis inhibitor conjugates or its polymorphs, enantiomers, stereoisomers, solvates, and hydrates thereof. These conjugates may be formulated as pharmaceutical compositions. The pharmaceutical compositions may be formulated for oral administration, intravenous, solution, syrup, sachet, transdermal administration, or injection. Such compositions may be used to treatment of cancer or its associated complications.