CAS: 182136-94-3; Dysidiolide
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专利信息
专利号:US-6482851-B1
优先权日:1998-02-04
标题 :Synthesis of dysidiolide and uses thereof
发明人：DANISHEFSKY SAMUEL J; MAGNUSON STEVEN R; ROSEN NEAL; SEPP-LORENZINO LAURA
权利人:SLOAN KETTERING INST CANCER; UNIV COLUMBIA
摘要:This invention provides a process for the preparation of a racemic mixture of dysidiolide a method for inhibiting growth of cancerous cells comprising contracting an amount of the racemic mixture of dysidiolide effective to inhibit the growth of said cells. Further provided is a method for treating cancer in a subject which comprises administering to the subject a therapeutically effective amount of the racemic mixture of dysidiolide.
专利号:WO-9940079-A1
优先权日:1998-02-04
标题 :Synthesis of dysidiolide and uses thereof
专利号:AU-2580299-A
优先权日:1998-02-04
标 题:Synthesis of dysidiolide and uses thereof
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参考文献:10.1016/j.bmcl.2004.03.100|10.1016/s0960-894x(04)00477-9
摘要:Shimazawa R, Suzuki T, Dodo K, Shirai R. Design and synthesis of dysidiolide analogs from vitamin D3: novel class of Cdc25A inhibitors. Bioorganic & Medicinal Chemistry Letters. 2004 Jun;14(12):3291–4. doi: 10.1016/j.bmcl.2004.03.100.
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