CAS: 1798-09-0; 3-Methoxyphenylacetic Acid

上下游产品

CAS号5020-41-7 2-(3-甲氧基苯基)乙醇 | CAS号201230-82-2 carbon monoxide | CAS号874-98-6 3-甲氧基苄溴 | CAS号824-98-6 间甲氧基氯苄 | CAS号66947-60-2 5-甲氧基二环[4.2.0]八... | CAS号18927-05-4 3-甲氧基苯乙酸甲酯 | CAS号6971-51-3 3-甲氧基苄醇 | CAS号124-38-9 二氧化碳 | CAS号5000-65-7 3'-甲氧基苯乙酰溴[用于高效... | CAS号84508-57-6 2-bromo-1,1-dim... | CAS号34624-38-9 2-(3-甲氧基苯基)乙酰肼 | CAS号35553-92-5 3-甲氧基苯基乙酸乙酯 | CAS号144828-84-2 N-甲氧基-2-(3-甲氧基苯... | CAS号5020-41-7 2-(3-甲氧基苯基)乙醇 | CAS号20772-11-6 1-Bromo-3-(3-me... | CAS号18463-71-3 2-(3-甲氧基苯基)乙酰胺 | CAS号591-31-1 3-甲氧基苯甲醛 | CAS号27752-28-9 7-methoxy-3a-me... | CAS号20876-29-3 2-硝基-5-甲氧基苯乙酸 | CAS号3027-13-2 3-甲氧基苯基丙酮

3-甲氧基氯苄置于cobalt Tetracarbonyl Anion Sodium Hydroxide体系中,用 甲醇 用作溶剂,化学反应 4.0H,以73%的收率获得3-甲氧基苯乙酸
参考文献:Rao,B. Nageswara; Adapa,Srinivas R.; Pardhasaradhi,M.,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1988,Vol. 27,# 1-12,P. 84-85
标题:Rao,B. Nageswara; Adapa,Srinivas R.; Pardhasaradhi,M.,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1988,Vol. 27,# 1-12,P. 84-85

专利信息

专利号:US-7109377-B2
优先权日:1996-10-16
标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
发明人：SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
权利人:HARVARD COLLEGE
摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

专利号:US-6177572-B1
优先权日:1997-08-20
标题 :Solid and liquid-phase synthesis of benzoxazoles and benzothiazoles and their use
发明人：WANG FENGJIANG
权利人:SEPRACOR INC
摘要:Methods for preparing benzoxazoles and benzothiazoles on solid supports. Substituted benzothiazoles and benzoxazoles, libraries of the compounds, and methods of using the compounds are also disclosed.

专利号:US-6664282-B2
优先权日:1999-09-17
标 题:Synthesis of [3,5,7]-1H-imidazo [1,5-a]imidazol-2 (3H)- one compounds
发明人：ELABDELLAOUI HASSAN M; OSTRESH JOHN M; HOUGHTEN RICHARD A
权利人:TORREY PINES INST
摘要:Individual substituted [3,5,7]-1H-imidazo[1,5-a]imidazol-2(3H)-one compounds and their pharmaceutically-acceptable salts are disclosed, as are libraries of such compounds. Methods of preparing and using the libraries of compounds as well as individual compounds of the libraries are also disclosed.

专利号:US-8350090-B1
优先权日:2011-08-24
标题 :Processes for preparing cyclopentenones and cyclopentenones for the synthesis of benzindene prostaglandins
发明人：WEI SHIH-YI; CHANG WAN-CHUN; YEH YU-CHIH
权利人:CHIROGATE INT INC; WEI SHIH-YI; CHANG WAN-CHUN; YEH YU-CHIH
摘要:The present invention provides novel processes of preparing racemic and optically active cyclopentenones of Formula I: n nThe invention also provides novel cyclopentenones of formula I in racemic or optically active form.

专利号:EP-0946499-B1
优先权日:1996-11-22
标 题 :N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
发明人：WU JING; TUNG JAY S; NISSEN JEFFREY S; MABRY THOMAS E; LATIMER LEE H; EID CLARK NORMAN; AUDIA JAMES E
权利人:ELAN PHARM INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit beta -amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits beta -amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions. Said compounds are represented by formula (I), wherein R<1> is selected from the group consisting of: a) alkyl, alkenyl, alkaryl, alkcycloalkyl, aryl, cycloalkyl, cycloalkenyl, heteroaryl and heterocyclic; b) a substituted phenyl group of formula (II), wherein R is alkylene of from 1 to 8 carbon atoms, m is an integer equal to 0 or 1, and c) 1- or 2-naphthyl substituted at the 5, 6, 7 and/or 8 positions, R<2> is selected from the group consisting of hydrogen, alkyl of from 1 to 4 carbon atoms, alkylalkoxy of from 1 to 4 carbon atoms, alkylthioalkoxy of from 1 to 4 carbon atoms; and R<3> and R<3'> are independently selected from the group consisting of: (a) hydrogen, (b) alkyl, (c) -(R<7>)n(W)p, wherein R<7> is an alkylene group, W is selected from the group consisting of (i) formula (A); (ii) heteroaryl; and (iii) N-heterocyclic, and n is an integer equal to 0 or 1, and p is an integer equal to 1 to 3; (d) -CH( phi )CH2C(O)O-Q where Q is selected from the group consisting of alkyl, aryl, heteroaryl and heterocyclic; X' is hydrogen, hydroxy or fluoro; X'' is hydrogen, hydroxy or fluoro, or X' and X'' together form an oxo group, Z is selected from the group consisting of a bond covalently linking R<1> to -CX'X''-, oxygen and sulfur.

专利号:US-6849650-B2
优先权日:1998-02-27
标 题:Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
发明人：THORSETT EUGENE D; PORTER WARREN J; NISSEN JEFFREY S; LATIMER LEE H; AUDIA JAMES E; DROSTE JAMES
权利人:ATHENA NEUROSCIENCES INC; LILLY CO ELI
摘要:Disclosed are compounds which inhibit β-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits β-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.