CAS: 133-89-1; Udp-A-D-Glucose

上下游产品

尿苷 5’-二二氧磷基半乳糖二钠盐 Uridine 5'-Diphospho-D-Galactose 2956-16-3
尿苷-5’-二磷酸 Udp 58-98-0
Uridine-5'-Diphospho-N-Acetyl-D-Galactosamine 7277-98-7
尿苷-5'-三磷酸 Utp 63-39-8
Uridine 5'-(β,γ-Methylene)Triphosphate 71850-06-1
尿苷5-单磷酸 5'-Uridylic Acid 58-97-9
5'-胞苷酸 Cytidine Monophosphate 63-37-6
尿嘧啶核苷 Uridine 58-96-8 Atp 56-65-5 Nadh 58-68-4

📜Uridine-5'-Phosphoimidazolide置于无机焦磷酸酶,Uridine-5'-Diphosphoglucose Pyrophosphorylase,Sodium Perchlorate,三丁基焦磷酸铵体系中,化学反应生成尿苷(5')二氢二磷酰(1)-Alpha-D-葡萄糖
参考文献:Convenient Syntheses Of Cytidine 5'-Triphosphate,Guanosine 5'-Triphosphate,And Uridine 5'-Triphosphate And Their Use In The Preparation Of Udp-Glucose,Udp-Glucuronic Acid,And Gdp-Mannose
标题:Convenient Syntheses Of Cytidine 5'-Triphosphate,Guanosine 5'-Triphosphate,And Uridine 5'-Triphosphate And Their Use In The Preparation Of Udp-Glucose,Udp-Glucuronic Acid,And Gdp-Mannose
摘要:
Doi:10.1021/jo00293A030

专利信息

专利号:US-5824472-A
优先权日:1986-03-24
标 题 :Process for the synthesis of sugar nucleotides using recombinant-DNA methods
发明人：BETLACH MICHAEL R; DOHERTY DANIEL H; VANDERSLICE REBECCA W
权利人:MONSANTO CO
摘要:A recombinant-DNA mediated method for the synthesis of sugar nucleotides is disclosed. This method utilizes portable DNA sequences capable of directing the microbial synthesis of various enzymes that catalyze the synthesis of sugar nucleotides, including UDP-glucose, UDP-glucuronic acid and GDP-mannose. The sugar moieties of these sugar nucleotides may subsequently be incorporated into industrially-useful polysaccharides such as xanthan gum. It has been found that vectors containing the portable DNA sequences described herein are capable both of causing sugar nucleotide production in microorganisms previously incapable of such synthesis and of causing increased sugar nucleotide production in organisms capable of synthesizing small quantities of these compounds. In particular, plasmids pAS7, pAS9 and pTS13 are disclosed. These plasmids are capable of directing sugar nucleotide synthesis in various hosts, including Xanthomonas sp. such as X. campestris and other organisms such as E. coli and various Pseudomonas sp.

专利号:US-12281135-B2
优先权日:2019-07-25
标 题 :Synthesis of 6-azido-6-deoxy-2-n-acetyl-hexosamine-nucleoside diphosphate
发明人：HOOGENBOOM JORIN; WIJDEVEN MARIA ANTONIA; VERKADE JORGE MERIJN MATHIEU; VAN DELFT FLORIS LOUIS; VAN BERKEL SANDER SEBASTIAAN
权利人:SYNAFFIX BV
摘要:The current invention concerns methods for the synthesis of 6-azido-6-deoxy-2-N-acetyl-monosaccharide-nucleoside diphosphate, in particular 6-azido-6-deoxy-2-N-acetyl-D-galactosamine-nucleoside diphosphate or 6-azido-6-deoxy-2-N-acetyl-D-glucosamine-nucleoside diphosphate. The synthesis method according to the invention is characterized by being highly efficient and high yielding. Also part of the present invention are key intermediates of this process.

专利号:US-6156547-A
优先权日:1990-04-16
标 题:Apparatus for the synthesis of saccharide compositions
发明人：ROTH STEPHEN
权利人:NEOSE PHARM INC
摘要:This invention relates to an apparatus containing specific binary combinations of glycosyltransferases, for the synthesis of specific saccharide compositions such as, for example, oligosaccharides, polysaccharides, glycolipids, and glycopeptides.

专利号:US-5866378-A
优先权日:1995-10-06
标 题:Process for the synthesis of nucleotide-6-deoxy-D-xylo-4-hexuloses
发明人：MARQUARDT RUEDIGER; HOERSCH BRIGITTE; SEIFFERT-STOERIKO ANDREAS; STEIN ANDREAS; ZERVOSEN ASTRID; ELLING LOTHAR; KULA MARIA REGINA; VERSECK STEFAN; DISTLER JUERGEN; PIEPERSBERG WOLFGANG
权利人:HOECHST AG
摘要:The present invention relates to processes for the enzymatic synthesis of nucleotide-6-deoxy-D-xylo-4-hexuloses starting from a nucleoside monophosphate (NMP). These processes comprise simultaneous incubation of the following substances in a buffer solution: n (a) substrates comprising a nucleoside monophosphate, phosphoenolpyruvate, adenosine triphosphate, and sucrose; and n (b) enzymes comprising pyruvate kinase, nucleoside-monophosphate kinase, sucrose synthase and deoxythymidine-D-glucose 4,6dehydratase.

专利号:WO-9720061-A1
优先权日:1995-11-30
标题:Synthesis of hyaluronic acid
发明人：WONG CHI-HUEY; DELUCA CLAUDIO
权利人:SCRIPPS RESEARCH INST; WONG CHI HUEY; DELUCA CLAUDIO
摘要:A preparative enzymatic synthesis of hyaluronic acid (HA) from UDP-N-acetyl-D-glucosamine (UDP-GlcNAc) and UDP-glucuronic acid (UDP-GlcA) catalyzed by hyaluronic acid synthase is coupled with regeneration of the sugar nucleotides. Polymerizing UDP-GlcA and UDP-GlcNAc to form hyaluronic acid results in the formation of released UDP. The released UDP is, in turn, employed in the regeneration of UDP-GlcA and UDP-GlcNAc. Use of the released UDP for regenerating UDP-GlcA and UDP-GlcNAc prevents a build-up of these compounds and prevents or reduces feed back inhibition of the hyaluronic acid synthase reaction that would otherwise be caused by such build-up. Accordingly, the product yield is enhanced by the recycling of these compounds.

专利号:WO-2024165611-A1
优先权日:2023-02-07
标题:Production of a disaccharide and/or milk oligosaccharide by a cell with reduced synthesis of udp-glcnac
发明人：BEAUPREZ JOERI; DECOENE THOMAS; VERCAUTEREN ANNELIES
权利人:INBIOSE NV
摘要:The present invention is in the technical field of synthetic biology, metabolic engineering and cell cultivation. The invention provides a cell for production of a disaccharide and/or an oligosaccharide like a milk oligosaccharide wherein synthesis of UDP-N-acetylglucosamine in said cell is rendered less functional. The invention further provides use of said cell in a cultivation or incubation. The invention also describes methods for the production of a disaccharide and/or an oligosaccharide like a milk oligosaccharide using said cell as well as the purification of said disaccharide and/or oligosaccharide like a milk oligosaccharide.