CAS: 13079-95-3; (1R,3As,4R,6As)-1,4-Bis(Benzo[d][1,3]Dioxol-5-yl)Hexahydrofuro[3,4-C]Furan
该化合物是一种自然产生的离子体,主要产自芝麻种子(Sesamum indicum),以其独特的立体化学和生物活性特性而著称,包括抗氧化剂和抗炎效应.复合物在调节脂肪新陈代谢和通过影响诸如细胞色素P450等酶途径支持肝健康方面的潜力,其高纯度和特征结构使它成为药理学和营养学研究的宝贵参考标准.(-)-萨辛也因其在增强线粒体功能和减轻氧化压力方面的作用而得到研究.对于分析和临床前应用来说,它具有适宜性,它得到了详细的光谱学和染色学验证,以确保科学研究中可再生.
- 英文名称(1R,3As,4R,6As)-1,4-Bis(Benzo[d][1,3]Dioxol-5-yl)Hexahydrofuro[3,4-C]Furan
- 中文名称(-)-芝麻素
- IUPAC名称(1R,3aS,4R,6aS)-1,4-bis(benzo[d][1,3]dioxol-5-yl)tetrahydro-1H,3H-furo[3,4-c]furan
- 其它别名1,3-Benzodioxole, 5,5'-(Tetrahydro-1H,3H-Furo(3,4-C)Furan-1,4-Diyl)Bis-, Cis-(-)-; 1,3-Benzodioxole, 5,5'-[(1R,3As,4R,6As)-Tetrahydro-1H,3H-Furo[3,4-C]Furan-1,4-Diyl]Bis-; (-)-Sesamin; (1R,3As,4R,6As)-1,4-Bis(Benzo[d][1,3]Dioxol-5-Yl)Hexahydrofuro[3,4-C]Furan
- CAS编号13079-95-3
- MFCD编号:MFCD31539878
- FDA UNII编号:9VCT11F572
- 分子式:C20H18O6分子量:354.36
- 产品CID: 467270
- 产品分类生物化工
物理性质
MSDS等安全信息
上下游产品
sesamin (3,4-methylenedioxy)phenylmagnesium bromide (1R,2S,3S,4R)-2,3-bis(hydroxymethyl)-1,4-bis(3,4-methylenedioxyphenyl)butane-1,4-diol 5-[(1E)-3-{(S)-1,3-benzodioxol-5-yl[(2S)-oxiran-2-yl]methoxy}prop-1-enyl]-1,3-benzodioxole Piperonylic acid dihydr°Cubebin (-)-eudesmin eudesmine合成工艺路线路线简述
📜[(1R,2R,3S,4R)-3-[(1R,2S,3R,4R)-3-[3-(1,3-Benzodioxol-5-yl)-3-Oxopropanoyl]Oxy-4,7,7-Trimethyl-2-Bicyclo[2.2.1]Heptanyl]-1,7,7-Trimethyl-2-Bicyclo[2.2.1]Heptanyl] 3-(1,3-Benzodioxol-5-yl)-3-Oxopropanoate置于lithium Aluminium Tetrahydride,4-甲基苯磺酸吡啶,Sodium Hydride体系中,用 四氢呋喃,N,N-二甲基甲酰胺,苯 用作溶剂,化学反应 31.5H,反应生成(-)-芝麻素
参考文献:Stereoselective Intramolecular Coupling Of Diaroylacetates Of (1R,1'r)-Exo,Exo'-3,3'-Biisoborneol By Oxidation With Br2
标题:Stereoselective Intramolecular Coupling Of Diaroylacetates Of (1R,1'r)-Exo,Exo'-3,3'-Biisoborneol By Oxidation With Br2
摘要:The Oxidative Coupling Of Diaroylacetate Derivatives Prepared From (1R,1'R)-Exo,Exo'-3,3'-Biisoborneol With Nah-Br-2 Gave The Corresponding Intramolecularly Coupled Products Stereoselectively. The Major (R,R)-Isomers Thus Obtained Were Transformed To (-)-Sesamin And (-)-Eudesmin. (C) 2003 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/s0957-4166(03)00572-X
海关参考信息
- 2902600000-乙苯
2905121000-正丙醇
2905399001-1,3-丙二醇
2905399002-1,4-丁二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
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📌 第三方产品分析报告
主要参考文献
参考标题:Concise Enantioselective Synthesis Of Furan Lignans (-)-Dihydrosesamin And (-)-Acuminatin And Furofuran Lignans (-)-Sesamin And (-)-Methyl Piperitol By Radical Cyclization Of Epoxides作者:Subhas Chandra Roy,Biplab Banerjee
摘要:Enantioselective Syntheses Of Furan Lignans (-)-Dihydrosesamin And (-)-Acuminatin And Furofuran Lignans (-)-Sesamin And (-)-Methyl Piperitol Were Achieved In Up To Only Three Steps In 43%, 42%, 63%, And 60% Overall Yield,Respectively, With High Optical Purity Through Stereoselective Intramolecular Radical Cyclization Of Suitably Substituted Epoxy Olefinic Ethers Using Bis(Cyclopentadienyl)Titanium(III)
合成参考文献
摘要:Hata, S.; Sibi, M. P., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 884.
摘要:Mondal, M.; Bora, U., Science of Synthesis: Metal-Catalyzed Cyclization Reactions, (2016) 2, 512.
参考文献:10.1007/bf02976626
摘要:Lee S, Kim BK, Cho SH, Shin KH. Phytochemical constituents from the fruits of Acanthopanax sessiliflorus. Arch Pharm Res. 2002 Jun;25(3):280–4. doi: 10.1007/bf02976626.
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