CAS: 119911-68-1; Cgrp 8-37 (Human)
该化合物是来自人类卡西通因基因相关浸化物(CGRP),特别是8至37残留物的支粒化碎片,它作为CGRP受体的竞争对手,有选择地阻塞其生物活动,在研究中广泛使用这种支粒,研究CGRP在血管变异,肝脏病理学和...
- 英文名称Cgrp 8-37 (Human)
- 中文名称降钙素基因相关肽片段
- 其它别名a-Calcitonin gene-related peptide(human), 1-de-L-alanine-2-de-L-cysteine-3-de-L-asparticacid-4-de-L-threonine-5-de-L-alanine-6-de-L-threonine-7-de-L-cysteine-; (8-37)-Human CGRP; 8-37-CGRP (human gene related); 8-37-calcitonin-peptide (human gene related); HCGRP-(8-37); Human CGRP(8-37); Human calcitonin gene-related peptide I (8-37); Human calcitonin gene-relatedpeptide(8-37); Human a-calcitonin gene-related peptide(8-37)
- CAS编号119911-68-1
- MFCD编号:MFCD00133153
- EINECS号:232-693-2
- 分子式:C139H230N44O38分子量:3125.59
- 产品CID: 264438
- 产品分类生物化工 → 多肽
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2912110000-甲醛
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合成参考文献
参考文献:10.1073/pnas.181191198
摘要:Paolocci N, Saavedra WF, Miranda KM, Martignani C, Isoda T, Hare JM, Espey MG, Fukuto JM, Feelisch M, Wink DA, Kass DA. Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling. Proc. Natl. Acad. Sci. U.S.A. 2001 Aug 21;98(18):10463–8. doi: 10.1073/pnas.181191198.
参考文献:10.1046/j.1365-201x.1996.431164000.x
摘要:RINDER J, LUNDBERG JM. Effects of hCGRP 8‐37 and the NK1‐receptor antagonist SR 140.333 on capsaicin‐evoked vasodilation in the pig nasal mucosa in vivo. Acta Physiologica Scandinavica. 1996 Feb;156(2):115–22. doi: 10.1046/j.1365-201x.1996.431164000.x.
参考文献:10.1046/j.1468-2982.1996.1605310.x
摘要:Jansen-Olesen I, Mortensen A, Edvinsson L. Calcitonin gene-related peptide is released from capsaicin-sensitive nerve fibres and induces vasodilatation of human cerebral arteries concomitant with activation of adenylyl cyclase. Cephalalgia. 1996 Aug;16(5):310–6. doi: 10.1046/j.1468-2982.1996.1605310.x.
参考文献:10.1111/j.1476-5381.1996.tb16698.x
摘要:Siney L, Brain SD. Involvement of sensory neuropeptides in the development of plasma extravasation in rat dorsal skin following thermal injury. British J Pharmacology. 1996 Mar;117(6):1065–70. doi: 10.1111/j.1476-5381.1996.tb16698.x.
参考文献:10.1111/j.1476-5381.1996.tb16737.x
摘要:Tomlinson AE, Poyner DR. Multiple receptors for calcitonin gene‐related peptide and amylin on guinea‐pig ileum and vas deferens. British J Pharmacology. 1996 Mar;117(6):1362–8. doi: 10.1111/j.1476-5381.1996.tb16737.x.
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