CAS: 108-23-6; Isopropyl Chloroformate

上下游产品

phosgene isopropyl alcohol trichloromethyl chloroformate bis(trichloromethyl) carbonateisopropyl pyridin-3-ylcarbamate isopropyl pyridin-2-ylcarbamate furfuryl-carbamic acid isopropyl ester 7-isopropoxycarbonylamino-3-phenyl-coumarin

甲酸异丙酯置于氯体系中,化学反应生成氯甲酸异丙酯
参考文献:甲酸异丙酯和甲酸叔丁酯的大气化学
标题:甲酸异丙酯和甲酸叔丁酯的大气化学
摘要:由于多种物质,特别是二烷基醚和乙烯基醚的氧化,在大气中形成了甲酸酯.这项工作描述了定义甲酸异丙酯hc(o)och(ch 3)2和甲酸叔丁酯hc(o)oc(ch 3)3的氧化机理的实验.氯和羟基引发的氧化均报告了产物分布,并提出了反应机理以解释所观测到的产物.拟议的机制包括α-酯重排反应,新型异构化途径和化学活化中间体的实例.Oh自由基对甲酸异丙酯在大气中的氧化作用产生以下产物(摩尔产率):乙酸甲酸酐(43%),丙酮(43%)和hcooh(15-20%).Oh自由基引发的甲酸叔丁酯的氧化产生丙酮,甲醛和co 2作为主要产品.衍生自标题化合物的两种酰基过氧硝酸盐的ir吸收截面.速率系数是针对甲酸异丙酯与oh(2.4+/-0.6)x10-12,与cl(1.75+/-0.35)x10-11以及与甲酸叔丁酯与cl(1.45+/-0.30 )反应的动力学而得出的)x10-11 Cm 3分子-1 S-1.简
Doi:10.1002/kin.20498

专利信息

专利号:WO-03031376-A1
优先权日:2001-10-12
标 题 :Solid phase synthesis of substituted 1,5-benzodiazepine-2-one and 1,5-benzothiazepine-2-one
发明人：MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
权利人:AVENTIS PHARMA INC; MORTON GEORGE C; SALVINO JOSEPH M; LABAUDINIERE RICHARD F; HERPIN TIMOTHY F
摘要:A solid phase synthetic method for making substituted 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one. The method is useful for synthesis of large numbers of compounds through automated parallel synthesis or combinatorial library generation and is thus important to rapid discovery or new therapeutic agents containing the base structure of 1,5-benzodiazepine-2-one or 1,5-benzothiazepine-2-one.

专利号:US-7138526-B1
优先权日:1999-06-15
标 题 :Solid phase synthesis of n,n-disubstituted diazacycloalkylcarboxy derivatives
发明人：HERPIN TIMOTHY F; MORTON GEORGE C; SALVINO JOSEPH M
权利人:AVENTIS PHARMA INC
摘要:A method for the solid phase synthesis of N,N-disubstituted diazacycloalkylcarboxy derivatives of general formula (I) and (II) is claimed. Examples include piperazine-2-carboxamide. The method is applicable to the synthesis or large combinatorial libraries

专利号:US-6127515-A
优先权日:1997-11-18
标 题:Functionalized resin for the synthesis of amides and peptides
发明人：MANFRE FRANCO; VANASSE BENOIT J; LABAUDINIERE RICHARD F; MORTON GEORGE C
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a functionalized amino resin of formula ##STR1## wherein S is a solid support; R is H or alkyl; A is ##STR2## Y is OH or OCOR 1 ; and R 1 is aliphatic or aromatic which is useful for the solid phase synthesis of amides, peptides and hydroxamic acids.

专利号:US-6133409-A
优先权日:1996-12-19
标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:WO-2006046949-A1
优先权日:2004-10-22
标 题 :SYNTHESIS AND ANTIMALARIAL ACTIVITY OF PYRROLO[3,2-f]QUINAZOLINE-1,3- DIAMINE DERIVATIVES
发明人：AI J LIN; JIAN GUAN; QUAN ZHANG; SKILLMAN DONALD R
权利人:WALTER REED ARMY INST OF RES W; AI J LIN; JIAN GUAN; QUAN ZHANG; SKILLMAN DONALD R
摘要:The invention relates to derivatives of pyrroloquinazolinediamine, more specifically derivatives of 7-(substituted)-7H-pyrrolo[3,2-F] quinazoline-1,3-diamines that are non-toxic and are also effective in the treatment of malaria, including P. falciparum and P.vivax strains. The derivatives are certain carbamate derivatives, succinimide derivatives, alkylcarboxamides derivatives and acetamide derivative, phthalimides, alkylamines and all other amide and imide derivatives and their 1-hydroxy analogs,. The derivatives of the present invention are also soluble in common organic solvents to facilitate the purification in a large scale synthesis of the composition.

专利号:US-2013338369-A1
优先权日:2011-03-07
标 题 :Process for the Synthesis of Aminobiphenylene
发明人：HEINRICH MARKUS; PRATSCH GERALD
权利人:HEINRICH MARKUS; PRATSCH GERALD; BASF SE
摘要:The present invention relates to a process for the synthesis of 2-aminobiphenylene and derivatives thereof by reacting a benzene diazonium salt with an aniline compound under basic reaction conditions.