CAS: 107017-73-2; Tert-Butyl (1-(Hydroxymethyl)Cyclopropyl)Carbamate

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115652-52-3 103500-22-7 107017-72-1

上下游产品

CAS号107259-05-2 1-(B°C-氨基)环丙烷甲酸乙酯 | CAS号88950-64-5 B°C-1-氨基环丙基甲酸 | CAS号308266-24-2 (N-tert-butoxyc... | CAS号66494-26-6 甲基1-(叔丁氧基羰基)环丙烷羧酸 | CAS号543-27-1 氯甲酸异丁酯 | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号107017-74-3 (1-((tert-Butox... | CAS号88950-64-5 B°C-1-氨基环丙基甲酸 | CAS号1027338-34-6 (1-(氨基甲基)环丙基)氨基甲酸叔丁酯 | CAS号107259-06-3 1-甲酰基环丙基氨基甲酸叔丁酯 | CAS号107017-72-1 1-氨基环丙甲醇 | CAS号115652-52-3 1-氨基环丙甲醇盐酸盐 | CAS号387845-49-0 N-B°C-1-(溴甲基)环丙胺

Boc-1-氨基环丙基甲酸置于n-甲基吗啉,氯甲酸异丁酯,Sodium Tetrahydroborate,水体系中,用 乙二醇二甲醚 用作溶剂,化学反应生成1-(Boc-氨基)环丙基甲醇
参考文献:Substituted Piperazino-Dihydrothienopyrimidines
标题:Substituted Piperazino-Dihydrothienopyrimidines
摘要:本发明涉及通式1的新哌啶二氢噻吩并嘧啶类化合物及其药理上可接受的盐,其中x为so或so2,优选so,并且其中r1,R2,R3和r4可具有权利要求1中所述的含义,以及含有这些化合物的药物组合物.这些新哌啶二氢噻吩并嘧啶类化合物适用于治疗呼吸系统或胃肠道疾病,关节,皮肤或眼睛的炎症性疾病,周围或中枢神经系统疾病或癌症.

专利信息

专利号:US-10227344-B2
优先权日:2016-06-24
标题 :CK2 inhibitors, compositions and methods thereof
发明人：WEBBER STEPHEN E; TAO XUELIANG; BRIN ELENA
权利人:POLARIS PHARMACEUTICALS INC
摘要:The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula (I), or a stereoisomer, a tautomer or a pharmaceutically acceptable salt thereof. n nFor Formula (I) compounds R 1 , R 2 , R 3 , Ar and Z are as defined in the specification. The inventive Formula (I) compounds are inhibitors of CK2 and find utility in any number of therapeutic applications, including but not limited to treatment of proliferative disorders such as cancer, inflammation and immunological disorders.

专利号:US-8129411-B2
优先权日:2005-12-30
标题:Organic compounds
发明人：EHARA TAKERU; GROSCHE PHILIPP; IRIE OSAMU; IWAKI YUKI; KANAZAWA TAKANORI; KAWAKAMI SHIMPEI; KONISHI KAZUHIDE; MOGI MUNETO; SUZUKI MASAKI; YOKOKAWA FUMIAKI
权利人:EHARA TAKERU; GROSCHE PHILIPP; IRIE OSAMU; IWAKI YUKI; KANAZAWA TAKANORI; KAWAKAMI SHIMPEI; KONISHI KAZUHIDE; MOGI MUNETO; SUZUKI MASAKI; YOKOKAWA FUMIAKI; NOVARTIS AG
摘要:The invention relates to 3,5-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,5-substituted piperidine compound, and/or a method of treatment comprising administering a 3,5-substituted piperidine compound, a method for the manufacture of a 3,5-substituted piperidine compound, and novel intermediates and partial steps for its synthesis. n The compounds have the formula I′ n nwherein R1, R2, T, R3 and R4 are as defined in the specification.