CAS: 10540-31-5; 4'-Fluoro-[1,1'-Biphenyl]-4-Carbonitrile

相似化合物

60992-98-5 72093-43-7 5731-10-2

上下游产品

CAS号623-03-0 对氯苯腈 | CAS号725735-33-1 triallyl(4-fluo... | CAS号3058-39-7 4-碘苯甲腈 | CAS号437-29-6 (p-fluorophenyl)3Bi | CAS号1765-93-1 4-氟苯硼酸 | CAS号10540-37-1 4-Fluoro-4'-iod... | CAS号544-92-3 氰化亚铜 | CAS号349-91-7 trichloro-(4-fl... | CAS号352-13-6 4-氟苯基溴化镁 | CAS号324-74-3 4-氟联苯 | CAS号324-74-3 4-氟联苯

📜4-氟-4'-羟基联苯置于4-二甲氨基吡啶,乙二醇二甲醚溴化镍,三乙胺,1,4-双(二苯基膦)丁烷,锌体系中,用 乙酸乙酯,乙腈 用作溶剂,化学反应 13.0H,反应生成4-(4-氟苯基)苯腈
参考文献:Zn(cn)2涉及c-o键断裂的镍催化苯酚衍生物的氰化
标题:Zn(cn)2涉及c-o键断裂的镍催化苯酚衍生物的氰化
摘要:开发了一种有效的镍催化的芳基磺酸盐,氟磺酸盐和氨基磺酸盐与zn(cn)2的氰化氰化物,该方法可轻松获得腈产品,通常收率非常好,收率极佳.该反应通过使用ni Ii配合物作为预催化剂和dmap作为添加剂来完成的.该方法还显示了广泛的功能组兼容性.例如,在反应过程中,酮,甲氧基,N,N-二甲基氨基,氰基,酯和吡啶基具有非常好的耐受性.
Doi:10.1021/acs.Joc.8B02498

专利信息

专利号:WO-2023167325-A1
优先权日:2022-03-03
标 题 :Immobilized palladium catalyst and method for producing same, and application of this catalyst to coupling reaction
发明人：YAMADA YOICHI; ZHANG ZHENZHONG; OHNO AYA
权利人:RIKEN
摘要:The present invention addresses the problem of developing a metal catalyst which is suitable for continuous flow organic synthesis reaction, is excellent in durability, and has high activity.　The present invention provides an immobilized palladium catalyst comprising a complex composed of palladium and a copolymer formed from (A) a repeating unit that has a certain substituted aromatic hydrocarbon ring and (B) a repeating unit that has a certain nitrogen-containing aromatic hetero ring.