CAS: 10041-02-8; 4-(Imidazol-1-yl)Phenol

相似化合物

7164-98-9 1353854-17-7 10040-95-6

上下游产品

CAS号288-32-4 咪唑 | CAS号106-41-2 对溴苯酚 | CAS号10040-95-6 1-(4-甲氧基苯基)-1H-咪唑 | CAS号540-38-5 4-碘苯酚 | CAS号78009-27-5 1-(1,3,5-tri-te... | CAS号104-94-9 对甲氧基苯胺 | CAS号104-92-7 对溴苯甲醚 | CAS号13633-25-5 4-苯基-1-丁基溴 | CAS号125279-79-0 艾生利特 | CAS号122958-17-2 N,N-diethyl-2-(...

1-(4-甲氧基苯基)-1H-咪唑置于2-二乙氨基乙硫醇盐酸盐,Sodium T-Butanolate体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应 2.0H,以78%的收率获得1-(咪唑-1-基)苯酚
参考文献:2-(二乙氨基)乙硫醇,一种无臭的芳香甲基醚脱保护新试剂
标题:2-(二乙氨基)乙硫醇,一种无臭的芳香甲基醚脱保护新试剂
摘要:报道了一种用于芳族甲基醚的脱保护的新试剂2-(二乙基氨基)乙硫醇.这种化合物以其hcl盐的形式商购可得,可在多种底物上以高至极好的收率提供相应的酚.与使用更常见的硫醇(如乙硫醇)相比,此方法的明显优势在于,通过用稀酸淬灭,可以轻松地将脱保护剂和副产物2-(二乙氨基)乙基甲基硫化物萃取到水相中,从而实现基本上无味的处理.
Doi:10.1021/jo0611059

专利信息

专利号:US-9890126-B2
优先权日:2012-04-24
标 题:Synthesis of novel inhibitors of isoprenoid biosynthesis (ISPF)
发明人：HAGEN TIMOTHY J; ZHANG ZHENG; LAZOWSKI ZACHARY; CLARE MICHAEL; BEGLEY DARREN W
权利人:UNIV NORTHERN ILLINOIS BOARD OF TRUSTEES; BERYLLIUM DISCOVERY CORP
摘要:Antibacterial and antimalarial IspF inhibitor compounds and compositions are described. Methods include administering described compounds and compositions to treat bacterial or parasitic infections and to inhibit parasite or bacterial growth.

专利号:US-2003138376-A1
优先权日:2000-03-17
标题 :Dosing form for reagents, use of said dosing form in organic chemical synthesis and production of said dosing form
发明人：RUHLAND THOMAS; HOLM PER; SCHULTZ KIRSTEN; HOLM JANNIE EGESKOV; ANDERSEN KIM
权利人:LUNDBECK & CO AS H
摘要:A dosing form for at least one solid reagent for use in conventional organic and inorganic synthesis, in parallel synthesis, and in split and mix synthesis in combinatorial chemistry is provided as compressed tablets each containing the same predetermined amount of said at least one reagent embedded in a polymer matrix comprising beads of a polymer insoluble in the solvents for the intended synthesis, which tablets are capable of disintegrating in said solvent for release of the at least one reagent and disperse the matrix as polymer beads into the solvent. The polymer beads forming the matrix and the reagents of the dosing form can easily be removed by filtration in order to separate these from a formed soluble product. n In a method for producing the dosing form, beads of one or more polymers are mixed with the reagents and compressed into tablets after pre-treatment with an aprotic organic solvent.

专利号:US-2015175582-A1
优先权日:2012-04-24
标 题:Design and synthesis of novel inhibitors of isoprenoid biosynthesis

专利号:US-2016257655-A1
优先权日:2012-04-24
标 题:Design and synthesis of novel inhibitors of isoprenoid biosynthesis (ispf)

专利号:EP-2841070-A2
优先权日:2012-04-24
标题:Design and synthesis of novel inhibitors of isoprenoid biosynthesis

专利号:US-9309232-B2
优先权日:2012-04-24
标 题:Synthesis of novel inhibitors of isoprenoid biosynthesis