CAS: 97511-05-2; 4-Bromodibenzo[b,D]Thiophene

该化合物是含有硫磺的七环化合物二苯并苯的溴衍生物,该化合物是有机合成的多用途中间体,特别是在开发制药,农用化学品和材料科学应用方面,其溴替代物可增强回弹性,从而能够产生诸如铃木-Miyaura或Buchwald-Hartwig的高效交叉反应.二苯并硫苯核心有助于其稳定性和电子特性,使其在光电子材料和协调化学方面有用.高纯度可用于确保研究和工业过程的一致性能.建议适当处理,因为其可能对光和湿度敏感.

英文名称4-Bromodibenzo[b,D]Thiophene
中文名称4-溴二苯并噻吩
IUPAC名称4-bromodibenzo[b,d]thiophene
其它别名4-溴二苯并[b,D]噻吩; Dibenzothiophene,4-Bromo-
CAS编号97511-05-2
MFCD编号:MFCD02683746
EINECS号:828-272-3
分子式:C12H7BrS
分子量:263.15
产品CID: 2021828
产品分类有机原料→分子砌块→芳杂环类化合物→苯并噻吩类化合物

相似结构搜索
InChIKey: GJXAVNQWIVUQOD-UHFFFAOYSA-N
InChI=1S/C12H7BrS/c13-10-6-3-5-9-8-4-1-2-7-11(8)14-12(9)10/h1-7H…
计算化学: 氢键受体数1.0氢键供体数0.0可旋转键数0.0

MSDS等安全信息

GHS象形图
GHS符号GHS07;
注释: Exclamation mark
危险类别特定目标器官毒性 - 单次接触类别3
皮肤腐蚀/刺激类别2
严重眼刺激类别2
警示词Warning(警告)
危险描述H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激.
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

欧盟法规

C&L通报

上下游产品

dibenzothiophene biphenyl dibenzo[b,d]thiophene-4-amine 4-Ethyldibenzothiophene 1-bromodibenzo[b,d]thiophene 1-bromo-4-dibenzothiopheneamine

合成工艺路线路线简述

合成目标产物 4-Bromodibenzothiophene 主要起始原料 Dibenzothiophene
132034-89-0 = 97511-05-2
反应条件:1.1 Catalysts: Bis(1,5-Cyclooctadiene)Nickel,4,4′-Bis(1,1-Dimethylethyl)-2,2′-Bipyridine Solvents: 1,4-Dioxane; 10 Min,Rt1.2 Reagents: Tetrabutylammonium Bromide Solvents: 1,4-Dioxane; 48 H,50 °C1.3 Reagents: Water; Rt
标题:Light-Promoted Nickel-Catalyzed Aromatic Halogen Exchange
作者:Feng,Yunhui; Luo,Hang; Zheng,Wanyao; Matsunaga,Shigeki; Lin,Luqing
参考文献:Acs Catalysis 日期:2022 卷标:12(18) 页码:11089-11096]

2007912-58-3 = 97511-05-2
反应条件:1.1 Reagents: Trifluoromethanesulfonic Acid Solvents: Pyridine,Water; Rt; 30 H,Reflux
标题:Preparation Of Aromatic Amines For Organic Electric Device
参考文献:Korea]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; -40 °C; 5 H,Rt; Rt -> -78 °C1.2 Reagents: 1,2-Dibromoethane Solvents: Tetrahydrofuran; -78 °C; 5 H,Rt
标题:Compound For Optoelectronic Device,Organic Light Emitting Diode Including The Same And Display Including The Organic Light Emitting Diode
参考文献:World Intellectual Property Organization]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Butyllithium,Bromine
标题:Heteroatom-Facilitated Lithiations
作者:Gschwend,Heinz W.; Rodriguez,Herman R.
参考文献:Organic Reactions (Hoboken 日期:1979 卷标:(1979)]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; 6 H,-40 °C -> 0 °C1.2 Reagents: 1,2-Dibromoethane; 14 H,-78 °C -> 20 °C
标题:Synthesis And Evaluation Of Dibenzothiophene Analogues As Pin1 Inhibitors For Cervical Cancer Therapy
作者:Wu,Ke-Jia; Liu,Xie; Wong,Suk-Yu; Zhou,Yuyang; Ma,Dik-Lung; Et Al
参考文献:Acs Omega 日期:2019 卷标:4(5) 页码:9228-9234]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran; -78 °C; 2 H,-78 °C -> 0 °C; 0 °C -> -78 °C1.2 Reagents: 1,2-Dibromoethane; 12 H,-78 °C -> Rt1.3 Reagents: Water; Rt
标题:Small Molecule Based On S,S-Dioxo-Dibenzothiophene And Phenanthro-Imidazole And Its Application In Organic Light-Emitting Device (Oled)
参考文献:China]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Bromine Solvents: Chloroform; 0 °C; 12 H,Rt
标题:Pyridine Derivative Compound As Electroluminescent Material For Organic Electroluminescent Device
参考文献:Korea]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Bromine Solvents: Chloroform; Rt -> 0 °C; 0 °C; 12 H,Rt
标题:Spiro Compounds As Electroluminescent Material For Organic Electroluminescent Device
参考文献:Korea]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Water; 1 H,-40 °C; -40 °C -> 0 °C; 6 H,0 °C1.2 Reagents: 1,2-Dibromoethane; -78 °C; 12 H,-78 °C
标题:Preparation Of Dibenzothiophene Compounds Containing Arylamine Moiety For Organic Electronic Device
参考文献:Korea]

2007912-58-3 = 97511-05-2
反应条件:1.1 Reagents: Trifluoromethanesulfonic Acid; 24 H,Rt1.2 Reagents: Pyridine Solvents: Water; Rt; 30 Min,Reflux
标题:Preparation Of Aromatic Heterocyclic Compounds For Organic Electric Device And Electronic Apparatus
参考文献:Korea]

106-93-4 + 132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; -40 °C; 5 H,0 °C; 0 °C -> -78 °C1.2 Solvents: Tetrahydrofuran; -78 °C; 5 H,0 °C
标题:Two Organic Host Materials For Organic Optoelectronic Element And Display Device
参考文献:World Intellectual Property Organization]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; -40 °C; 5 H,Rt; Rt -> -78 °C1.2 Reagents: 1,2-Dibromoethane Solvents: Tetrahydrofuran; -78 °C; 5 H,Rt
标题:Organic Compounds For Organic Optoelectronic Devices,Organic Emitting Diodes,And Display Devices
参考文献:European Patent Organization]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran; -40 °C1.2 Reagents: Dibromoethane; -78 °C -> Rt
标题:Dibenzothiophene
作者:Benoit,Guillaume
参考文献:E-Eros Encyclopedia Of Reagents For Organic Synthesis 日期:2014 页码:1-4]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; -40 °C; -40 °C -> 0 °C; 6 H,0 °C1.2 Reagents: 1,2-Dibromoethane Solvents: Tetrahydrofuran; -78 °C; Overnight,Rt
标题:A Phosphorescent C-C* Cyclometalated Platinum(Ii) Dibenzothiophene Nhc Complex
作者:Tronnier,Alexander; Risler,Anita; Langer,Nicolle; Wagenblast,Gerhard; Muenster,Ingo; Et Al
参考文献:Organometallics 日期:2012 卷标:31(21) 页码:7447-7452]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane; -40 °C; 6 H,0 °C; 0 °C -> -78 °C1.2 Reagents: 1,2-Dibromoethane Solvents: Tetrahydrofuran; -78 °C; 14 H,Rt
标题:Preparation Of 5-Membered Heterocycles For Organic Light-Emitting Diodes
参考文献:Korea]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Butyllithium Solvents: Tetrahydrofuran,Hexane1.2 Reagents: 1,2-Dibromoethane Solvents: Tetrahydrofuran1.3 Solvents: Dichloromethane
标题:A New Synthesis Of Fungicidal Methyl (E)-3-Methoxypropenoates
作者:Rossi,Renzo; Bellina,Fabio; Ciucci,Donatella; Carpita,Adriano; Fanelli,Corrado
参考文献:Tetrahedron 日期:1998 卷标:54(26) 页码:7595-7614]

17909-03-4 = 97511-05-2
反应条件:1.1 Reagents: Zinc Chloride,Benzyltrimethylammonium Tribromide Solvents: Acetic Acid
标题:Studies Towards Dibenzothiophene-S-Oxide Arrays And Their Photochemical Reactivity
作者:Thiemann,Thies; Kumazoe,Kazuya; Arima,Kazuya; Mataka,Shuntaro
参考文献:International Electronic Conferences On Synthetic Organic Chemistry 日期:2004 卷标:(2004) 页码:1537-1550]

17909-03-4 = 97511-05-2
反应条件:1.1 Reagents: Zinc Chloride,Benzyltrimethylammonium Tribromide Solvents: Acetic Acid
标题:Studies Towards Dibenzothiophene S-Oxide Arrays And Their Photochemical Reactivity
作者:Thiemann,Thies; Kumazoe,Kazuya; Arima,Kazuya; Mataka,Shuntaro
参考文献:Kyushu Daigaku Kino Busshitsu Kagaku Kenkyusho Hokoku 日期:2001 卷标:15(1) 页码:63-71]

132-65-0 = 97511-05-2
反应条件:1.1 Reagents: Butyllithium; -78 °C -> 0 °C1.2 Reagents: 1,2-Dibromoethane; -78 °C -> Rt
标题:Non-Doped Deep Blue And Doped White Electroluminescence Devices Based On Phenanthroimidazole Derivative
作者:Chen,Shuo; Wu,Yukun; Hu,Shoucheng; Zhao,Yi; Fang,Daining
参考文献:Journal Of Fluorescence 日期:2017 卷标:27(2) 页码:451-461

二苯并噻吩置于正丁基锂,1,2-二溴乙烷体系中,化学反应生成 4-溴二苯并噻吩
参考文献:基于苯并咪唑衍生物的无掺杂深蓝和掺杂白电致发光器件
标题:基于苯并咪唑衍生物的无掺杂深蓝和掺杂白电致发光器件
摘要:合成了一种新型的基于吩噻咪唑的深蓝色发射体phimpotd,将其与给电子二苯并噻吩单元,吸电子菲并咪唑和二苯基膦氧化物部分结合.此外,弱的π-π堆积和分子间聚集使固态的光致发光量子产率高达0.34.基于phimpotd发射器的非掺杂有机发光二极管(oled)表现出3.6 V的低导通电压,1.13 Cd A-1的有利效率以及国际照明委员会(cie)坐标的深蓝色发射(0.15,0.08).cie非常接近ntsc(国家电视标准委员会)蓝色标准(cie:0.14,0.08).飞镖还用作蓝光发射器,并用作黄光发射器(po-01)的主体,以制造白色有机发光二极管(woled).在1000 Cd M-2的亮度下,前视最大ce为4.83 Cd A-1,Cie坐标为(0.32,0.32).而且,单载波设备清楚地证明了phimpotd的典型双极主导特性.这项工作不仅证明了菲并咪唑单元是构建深蓝色发射材料
DOI:10.1007/s10895-016-1970-5

专利信息

专利号:WO-2023122754-A1
优先权日:2021-12-23
标题 :Processes and intermediates for preparing gb13, gb22 and himgaline
发明人：LANDWEHR ELEANOR; SHENVI RYAN; BAKER MEGHAN; OGUMA TAKUYA
权利人:SCRIPPS RESEARCH INST
摘要:Provided herein are processes for the streamlined synthesis of Galbulimima alkaloids, such as himbadine, isolated from Galbulimima belgraveana and G. baccatta, trees endemic to the rainforests of Northern Australia and Papua New Guinea, as well as analogs thereof, such as GB13, GB16, GB22, and himgaline, and further including intermediates useful in the synthesis of these and related compounds.