CAS: 765-69-5; 2-Methylcyclopentane-1,3-Dione

相似化合物

3883-58-7 3859-39-0 823-36-9

上下游产品

CAS号17082-61-0 1,2-双(三甲基硅氧基)环丁烯 | CAS号534-15-6 乙缩醛二甲醇 | CAS号4505-54-8 3-甲基环戊烷-1,2,4-三酮 | CAS号781-38-4 (3-甲基-2,4,5-三氧代... | CAS号110-15-6 琥珀酸； 丁二酸 | CAS号79-03-8 丙酰氯 | CAS号108-30-5 丁二酸酐 | CAS号3883-57-6 3-(乙酰氧基)-2-甲基-2... | CAS号20279-38-3 SUCCINIC ACID M... | CAS号924-88-9 丁二酸二异丙酯 | CAS号22117-97-1 2-methyl-3-(2-m... | CAS号22592-18-3 5-Heptyn-2-one ... | CAS号25112-78-1 2-methyl-2-(3-o... | CAS号25110-82-1 3-(7a-methyl-1,... | CAS号106-65-0 琥珀酸二甲酯 | CAS号35544-95-7 (3aR,7aR)-3a-hy... | CAS号33879-04-8 (+)-六氢-3a-羟基-7a...

2-(1-Ethoxy-Ethyl)-2-Trimethylsilanyloxy-Cyclobutanone置于nafion-H,三氟乙酸体系中,化学反应 10.0H,反应生成 2-甲基-1,3-环戊二酮
参考文献:Martinez,Rodolfo A.; Rao,Pemmaraju N.; Kim,Hyun K.,Synthetic Communications,1989,Vol. 19,# 3And4,P. 373-378
标题:Martinez,Rodolfo A.; Rao,Pemmaraju N.; Kim,Hyun K.,Synthetic Communications,1989,Vol. 19,# 3And4,P. 373-378

专利信息

专利号:US-4110380-A
优先权日:1974-05-06
标题 :Asymmetric synthesis of organic compounds
发明人：HAJOS ZOLTAN GEORGE; PARRISH DAVID RICHARD
权利人:HOFFMANN LA ROCHE
摘要:Optically active organic compounds are prepared starting from optically inactive reactants by means of an optically active agent which influences the course of the reaction. In particular optically active compounds having a 'meso' type carbon atom undergo an intramolecular ring closure in the presence of an optically active agent to yield an optically active product having one additional ring. The present process is particularly useful in the preparation of optically active bicyclic diketones which are important intermediates in the total synthesis of steroids.

专利号:US-3962291-A
优先权日:1974-09-05
标 题:Total synthesis of 11-alkyl steroids
发明人：GARLAND ROBERT B; PAPPO RAPHAEL
权利人:SEARLE & CO
摘要:A novel total synthesis of 11-alkyl steroids, utilizing readily available and inexpensive raw materials, is described. The resulting products are useful and novel pharmacological agents possessing, for example, selective hormonal properties.

专利号:US-4045452-A
优先权日:1974-03-13
标题 :Steroid total synthesis process utilizing a cyanoalkyl A-ring precursor
发明人：COHEN NOAL; ROSENBERGER MICHAEL; SAUCY GABRIEL
权利人:HOFFMANN LA ROCHE
摘要:A multi-step, stereospecific total synthesis of steroids utilizing intermediates having a cyanoalkyl A-ring precursor is disclosed. The initial starting materials for this process are the relatively inexpensive and commercially available reagents γ-butyrolactone and sodium cyanide. The process is suitable for the preparation of racemic or optically active, medicinally valuable steroids, particularly 19-norsteroids. It is a feature of this process that conditions employed during the multiple step synthesis are selected so as to retain the normally labile nitrile group even during hydrogenation and hydrolysis steps. In this manner, it is possible to employ the nitrile group as an A-ring precursor without resorting to protective groups as wasl heretofore found necessary in previous steroid total synthesis processes.

专利号:US-4105676-A
优先权日:1975-12-22
标题 :Steroid total synthesis process utilizing a cyanoalkyl a-ring precursor
发明人：COHEN NOAL; ROSENBERGER MICHAEL; SAUCY GABRIEL
权利人:HOFFMANN LA ROCHE
摘要:A multi-step, stereospecific total synthesis of steroids utilizing intermediates having a cyanoalkyl A-ring precursor is disclosed. The initial starting materials for this process are the relatively inexpensive and commercially available reagents γ-butyrolactone and sodium cyanide. The process is suitable for the preparation of racemic or optically active, medicinally valuable steroids, particularly 19-norsteroids. It is a feature of this process that conditions employed during the multiple step synthesis are selected so as to retain the normally labile nitrile group even during hydrogenation and hydrolysis steps. In this manner, it is possible to employ the nitrile group as an A-ring precursor without resorting to protective groups as was heretofore found necessary in previous steroid total synthesis processes.

专利号:US-3965138-A
优先权日:1974-03-13
标 题:Steroid total synthesis process utilizing a cyanoalkyl A-ring precursor
发明人：COHEN NOAL; ROSENBERGER MICHAEL; SAUCY GABRIEL
权利人:HOFFMANN LA ROCHE
摘要:A multi-step, stereospecific total synthesis of steroids utilizing intermediates having a cyanoalkyl A-ring precursor is disclosed. The initial starting materials for this process are the relatively inexpensive and commercially available reagents γ-butyrolactone and sodium cyanide. The process is suitable for the preparation of racemic or optically active, medicinally valuable steroids, particularly 19-norsteroids. It is a feature of this process that conditions employed during the multiple step synthesis are selected so as to retain the normally labile nitrile group even during hydrogenation and hydrolysis steps. In this manner, it is possible to employ the nitrile group as an A-ring precursor without resorting to protective groups as was heretofore found necessary in previous steroid total synthesis processes.

专利号:US-3898265-A
优先权日:1970-08-26
标 题 :Steriod total synthesis process utilizing a cyanoalkyl A-ring precursor
发明人：COHEN NOAL; ROSENBERGER MICHAEL; SAUCY GABRIEL
权利人:HOFFMANN LA ROCHE
摘要:A multi-step, stereospecific total synthesis of steroids utilizing intermediates having a cyanoalkyl A-ring precursor is disclosed. The initial starting materials for this process are the relatively inexpensive and commercially available reagents gamma -butyrolactone and sodium cyanide. The process is suitable for the preparation of racemic or optically active, medicinally valuable steroids, particularly 19-norsteroids. It is a feature of this process that conditions employed during the multiple step synthesis are selected so as to retain the normaly labile nitrile group even during hydrogenation and hydrolysis steps. In this manner, it is possible to employ the nitrile group as an A-ring precursor without resorting to protective groups as was heretofore found necessary in previous steroid total synthesis processes.