专利号:US-2021107859-A1 优先权日:2018-04-06 标题 :A process for the synthesis of carbon labeled organic compounds 发明人:AUDISIO DAVIDE; CANTAT THIBAULT; DESTRO GIANLUCA 权利人:COMMISSARIAT ENERGIE ATOMIQUE 摘要:A process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group is described. A method of using carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; a process for manufacturing labeled pharmaceuticals and agrochemicals comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; and a process for producing tracers comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure are also described.
专利号:WO-2013018053-A1 优先权日:2011-08-02 标题 :Process for the preparation of epoxides as intermediates for the synthesis of nebivolol 发明人:CIPOLLONE AMALIA; D ANDREA PIERO; FATTORI DANIELA 权利人:MENARINI INT OPERATIONS LU SA; CIPOLLONE AMALIA; D ANDREA PIERO; FATTORI DANIELA 摘要:The present invention relates to a novel process of synthesis of epoxides, 6-fluoro-2- (oxiran-2-yl) chroman (Figure 1), intermediates for the synthesis of nebivolol, depicted in Scheme (1), enabling to obtain the above- mentioned epoxides in a racemic or semichiral form.
专利号:US-5530168-A 优先权日:1994-10-03 标题 :Process for the synthesis of a C2 + Aliphatic alcohol in a slurry reactor comprising an in-situ catalyst impregnation step 发明人:UNDERWOOD RICHARD P; TOSELAND BERNARD A; DAHL THOMAS A; HUGO JANET F 权利人:AIR PROD & CHEM 摘要:A process is set forth for the synthesis of a C2+ aliphatic alcohol from hydrogen and carbon oxides in the presence of a copper-based catalyst which has been impregnated with an alkali metal compound. The process differs from the prior art in that the catalyst is impregnated with the alkali metal compound in the same slurry reactor which is used for reacting the hydrogen and carbon oxides. By contrast, in the prior art C2+ aliphatic alcohol synthesis, impregnation of the copper-based catalyst with the alkali metal compound is accomplished by a separate step in a separate vessel. By eliminating this separate step, the present invention realizes a savings in processing and equipment costs.
专利号:US-6835849-B2 优先权日:2002-07-15 标题:Synthesis of alkenoate esters from lactones and alcohols 发明人:MANZER LEO ERNEST 权利人:DU PONT 摘要:The invention relates to the synthesis of alkenoate esters from a corresponding lactone and an alcohol in the presence of a basic catalyst. More specifically, this invention relates to the synthesis of methyl-4-pentenoate ester from 5-methyl butyrolactone and methanol.
专利号:US-5856259-A 优先权日:1994-12-21 标 题:Preparation process of supported catalyst for the synthesis of methacrolein and methacrylic acid 发明人:WATANABE SEIGO; YOSHIOKA HITOSHI; IZUMI JINKO 权利人:MITSUBISHI RAYON CO 摘要:A process for producing a supported catalyst for the synthesis of methacrolein and methacrylic acid in which a catalytic active substance comprising a composite oxide containing molybdenum and bismuth as essential components is supported on the inside surface and/or the outside surface of an inert carrier, which comprises the steps of drying a mixed solution or an aqueous slurry containing the compounds of the elements constituting the catalytic active substance, subjecting the dried product to a primary calcination at a temperature in a range of 200°-400° C. to form a catalytic active substance precursor, comminuting the obtained catalytic active substance precursor to such an extent that the medium particle size in the volume-based particle size distribution becomes 10 μm or less, supporting the comminution product on an inert carrier, and subjecting it to a secondary calcination at a temperature which is 100° C. or more higher than the primary calcination temperature.
专利号:US-5859288-A 优先权日:1995-03-24 标 题:Reagent and process for the synthesis of oxysulphide-containing fluorine-containing organic derivatives 发明人:FORAT GERARD; MAS JEAN-MANUEL; SAINT-JALMES LAURENT 权利人:RHONE POULENC CHIMIE 摘要:The invention relates to a reagent which is useful for the synthesis of oxysulphide-containing fluorine-containing organic derivatives by reacting with an oxide of sulphur, especially sulphur dioxide, characterized in that it comprises: a) a fluorocarboxylic acid of formula Ew-CF2-COOH where Ew is an electron-withdrawing group or atom which is at least partially salified by an organic or inorganic cation, and b) an aprotic polar solvent; and in that the content of releasable protons carried by its various components, including their impurities, is at most equal to half the initial molar concentration of the said fluorocarboxylic acid. This reagent can be used by heating in order to form fluorine-containing sulphinic or sulphonic acids.
参考文献:10.1128/jb.103.1.153-158.1970 摘要:Dunn JH, Wolk CP. Composition of the Cellular Envelopes of Anabaena cylindrica. J Bacteriol. 1970 Jul;103(1):153–8. doi: 10.1128/jb.103.1.153-158.1970. 参考文献:10.1016/j.jhazmat.2011.06.012 摘要:Wang TH, Chen CL, Ou LY, Wei YY, Chang FL, Teng SP. Cs sorption to potential host rock of low-level radioactive waste repository in Taiwan: experiments and numerical fitting study. J Hazard Mater. 2011 Sep 15;192(3):1079–87. doi: 10.1016/j.jhazmat.2011.06.012. 参考文献:10.1021/ic200722a 摘要:Jakobsen HJ, Bildsøe H, Skibsted J, Brorson M, Hung I, Gan Z. Synthesis of 17O-Labeled Cs2WO4 and Its Ambient- and Low-Temperature Solid-State 17O MAS NMR Spectra. Inorg. Chem. 2011 Jul 19;50(16):7676–84. doi: 10.1021/ic200722a. 参考文献:10.1093/nar/gki979 摘要:McCabe CD, Innis JW. A genomic approach to the identification and characterization of HOXA13 functional binding elements. Nucleic Acids Res. 2005;33(21):6782–94.