CAS: 452316-31-3; 2-Acetamido-6-O-(2-Acetamido-2-Deoxy-B-D-Glucopyranosyl)-2-Deoxy-D-Galactopyranose

该化合物是一种复杂的分酸衍生物,在球菌生物学和碳水化合物化学中具有重大关联性.该化合物的特点是N-乙酰基甲胺(GalNAc)和N-乙酰基...

英文名称2-Acetamido-6-O-(2-Acetamido-2-Deoxy-B-D-Glucopyranosyl)-2-Deoxy-D-Galactopyranose
中文名称2-(乙酰氨基)-6-O型[2-(乙酰氨基)-2-脱氧-β-D-吡喃葡萄糖]-2-脱氧-α-D-半乳糖
IUPAC名称N-((2R,3R,4R,5S,6R)-2-(((2R,3R,4R,5R)-5-acetamido-3,4,6-trihydroxytetrahydro-2H-pyran-2-yl)methoxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide
其它别名2-Acetamido-2-Deoxy-6-O-(β-D-2-Acetamido-2-Deoxyglucopyranosyl)-α-D-Galactopyranose; 2-(Acetylamino)-6-O-[2-(Acetylamino)-2-Deoxy-β-D-Glucopyranosyl]-2-Deoxy-α-D-Galactose; Glcnac1β-6Galnac; 2-Acetamido-2-Deoxy-6-O-(2-Acetamido-2-Deoxy-B-D-Glucopyranosyl)-D-Galactopyranose; 2-Acetamido-2-Deoxy-6-O-(β-D-2-Acetamido-2-Deoxyglucopyranosyl)-α-D-Galactopyranose Usp/ep/bp; α-D-Galactopyranose, 2-(Acetylamino)-6-O-[2-(Acetylamino)-2-Deoxy-β-D-Glucopyranosyl]-2-Deoxy-; 2-Acetamido-6-O-(2-Acetamido-2-Deoxy-B-D-Glucopyranosyl)-2-Deoxy-D-Galactopyranose; 2-Acetamido-2-Deoxy-6-O-(β-D-2-Acetamido-2-Deoxyglucopyranosyl)-α-D-Galactopyranose
CAS编号452316-31-3
分子式:C16H28N2O11分子量:424.4
产品CID: 1456868
产品分类生物化工 → 糖类化合物 → 寡糖

相似结构搜索
InChIKey: ZNYQSCCJIAFAQX-CHCYTSQNSA-N
InChI=1S/C16H28N2O11/c1-5(20)17-9-13(24)12(23)8(28-15(9)26)4-27-16-10(18-6(2)21)14(25)11(22)7(3-19)29-16/h7-16,19,22-26H,3-4H2,1-2H3,(H,17,20)(H,18,21)/t7-,8-,9-,10-,11-,
计算化学: 氢键受体数11.0氢键供体数8.0可旋转键数6.0

MSDS等安全信息

上下游产品

2-乙酰氨基-2-脱氧-D-吡喃半乳糖 N-Acetyl-D-Galactosamine 1136-42-1
4-硝基苯基-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖苷 4-Nitrophenyl N-Acetyl-β-D-Glucosaminide 3459-18-5

合成工艺路线路线简述

📜2-乙酰氨基-2-脱氧-D-吡喃半乳糖,4-硝基苯基-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖苷置于sodium-Phosphate Buffer体系中,用水作为反应溶剂,化学反应 30.0H,以26%的收率获得产物2-(乙酰氨基)-6-O型[2-(乙酰氨基)-2-脱氧-β-D-吡喃葡萄糖]-2-脱氧-α-D-半乳糖
参考文献:使用米曲霉的n-乙酰基己糖苷酶和圆芽孢杆菌的β-半乳糖苷酶,用糖苷酶催化的二糖,三糖和四糖寡糖合成
标题:使用米曲霉的n-乙酰基己糖苷酶和圆芽孢杆菌的β-半乳糖苷酶,用糖苷酶催化的二糖,三糖和四糖寡糖合成
摘要:所述ñ从-Acetylhexosaminidase米曲霉的催化转移ñ-Acetylglucosaminyl和ñ-Acetylgalactosaminyl残基选择性地到6-Oh基团的ñ-Acetylgalactosamine,得到相应的(1->6)-连接的二糖3和6在26和38%产量分别.二糖β-D-Glc P Nac-(1->6)-β-D-Gal P伏隔3这样合成充当受体用于传送的β-D半乳糖残基由相应的p硝基苯基糖苷到4非还原单元的-Oh基团产生卵巢囊液粘蛋白片段β-D-Gal P-(1->4)-β-Glc P Nac-(1->6)-D-Gal P伏隔8产率48%与四糖β-一起d-Gal P-(1->4)-β-D-Gal-(1->4)-β-D-Glc P Nac-(1->6)-D-Gal P Nac 9,产率为7%.以乳糖为受体,在人肠双歧杆菌的生长因子中产生了三糖β-
DOI:10.1039/p19960001921