CAS: 4498-99-1; P-Tolylmethanethiol

上下游产品

CAS号104-81-4 4-甲基溴苄 | CAS号60410-77-7 bis(4-methylben... | CAS号589-18-4 4-甲基苄醇 | CAS号115412-23-2 (4-methylbenzyl... | CAS号76950-78-2 1-(4-methylbenz... | CAS号861078-32-2 dithi°Carbamic ... | CAS号13250-88-9 Benzene,1,1'-[t... | CAS号104-82-5 对甲基氯苄 | CAS号51419-59-1 4-甲基苄磺酰氯 | CAS号106-42-3 对二甲苯 | CAS号538-39-6 1,2-二对甲苯基乙烷 | CAS号13250-88-9 Benzene,1,1'-[t... | CAS号104-87-0 对甲基苯甲醛 | CAS号18869-29-9 4,4-二甲基-反-二苯乙烯 | CAS号61925-78-8 N-B°C-S-4-甲基苄基-... | CAS号3287-02-3 1-甲基-4-(苯乙炔基)苯 | CAS号33155-60-1 对叔丁基苯乙酸甲酯 | CAS号14062-19-2 4-甲基苯基乙酸乙酯

📜(4-甲基苯基)甲醇置于劳森试剂体系中,用 甲苯 作为反应溶剂,化学反应 48.0H,反应生成 4-甲基苄基硫醇
参考文献:原位反应生成的半硫缩醛的非酶动力学动力学拆分:访问1,3-二取代的邻苯二甲酰胺.
标题:原位反应生成的半硫缩醛的非酶动力学动力学拆分:访问1,3-二取代的邻苯二甲酰胺.
摘要:开发了半硫缩醛的第一个非酶促dkr反应.半硫缩醛是通过添加硫醇原位形成的,随后进行了分子内的氧杂-迈克尔反应.反应的范围很广,从脂族取代基到芳族取代基,均以非常好的收率,中等的非对映选择性和高对映选择性获得了1,3-二取代-1,3-二氢异苯并呋喃产物.
DOI:10.1002/adsc.201701518

专利信息

专利号:US-7589170-B1
优先权日:1998-09-25
标题 :Synthesis of cyclic peptides
发明人：SMYTHE MARK LESLIE; MEUTERMANS WIM DENIS FRANS; BOURNE GREGORY THOMAS; MCGEARY ROSS PETER
权利人:UNIV QUEENSLAND
摘要:This invention relates to methods for preparing cyclic peptides and peptidomimetic compounds in solution and bound to solid supports, and to cyclic peptide or peptidomimetic libraries for use in drug screening programs. In particular, the invention relates to a generic strategy for synthesis of cyclic peptides or peptidomimetics that enables the efficient synthesis under mild conditions of a wide variety of desired compounds. Two approaches were evaluated for their improvements in solution and solid phase synthesis of small cyclic peptides: positioning reversible N-amide substituents in the sequence; and applying native ligation chemistry in an intramolecular sense. Systematic investigation of the effects of preorganising peptides prior to cyclisation by using peptide cyclisation auxiliaries, and developing new linkers and peptide cyclisation auxiliaries to aid cyclic peptide synthesis gives surprising improvements in both yields and purity of products compared to the prior art methods. The combination of these technologies provides a powerful generic approach for the solution and solid phase synthesis of small cyclic peptides. The ring contraction and N-amide substitution technology of the invention provide improved methods for the synthesis of cyclic peptides and peptidomimetics. When used in conjunction with linker strategies, this combination provides solid-phase avenues to cyclic peptides and peptidomimetics.

专利号:US-5331096-A
优先权日:1992-04-01
标题 :2- and 3-sulfur derivatives of 1,5-iminosugars
发明人：KOSZYK FRANCIS J; MUELLER RICHARD A
权利人:SEARLE & CO
摘要:Novel derivatives of 1-deoxynojirimycin are disclosed which have thio or sulfinyl substituents at C-2 or C-3. These compounds are useful inhibitors of lentiviruses such as visna virus and human immunodeficiency virus. Methods of chemical synthesis of these derivatives and intermediates therefor are also disclosed.

专利号:US-5342951-A
优先权日:1992-04-01
标题:2- and 3-sulfur derivatives of 1,5-iminosugars
发明人：KOSZYK FRANCIS J; MUELLER RICHARD A
权利人:SEARLE & CO
摘要:Novel derivatives of 1-deoxynojirimycin are disclosed which have thio or sulfinyl substituents at C-2 or C-3. These compounds are useful inhibitors of lentiviruses such as visna virus and human immunodeficiency virus. Methods of chemical synthesis of these derivatives and intermediates therefor are also disclosed.

专利号:US-5268482-A
优先权日:1992-04-01
标 题:2- and 3-sulfur derivatives of 1,5-iminosugars
发明人：KOSZYK FRANCIS J; MUELLER RICHARD A
权利人:SEARLE & CO
摘要:Novel derivatives of 1-deoxynojirimycin are disclosed which have thio or sulfinyl substituents at C-2 or C-3. These compounds are useful inhibitors of lentiviruses such as visna virus and human immunodeficiency virus. Methods of chemical synthesis of these derivatives and intermediates therefor are also disclosed.

专利号:US-9185909-B2
优先权日:2007-09-17
标 题:Synthesis of resveratrol-based natural products
发明人：SNYDER SCOTT ALAN; BREAZZANO STEVEN P; ROSS AUDREY G; LIN YUNQING; ZOGRAFOS ALEXANDROS L
权利人:SNYDER SCOTT ALAN; BREAZZANO STEVEN P; ROSS AUDREY G; LIN YUNQING; ZOGRAFOS ALEXANDROS L; UNIV COLUMBIA
摘要:Processes for synthesizing resveratrol-based oligomers are provided. In addition, resveratrol-based oligomer compounds free of plant extract are provided.

专利号:WO-0018790-A1
优先权日:1998-09-25
标 题 :Synthesis of cyclic peptides