CAS: 4104-45-4; 3-(Methylthio)Propylamine

相似化合物

2419-62-7 773803-59-1 70961-63-6

上下游产品

-1H-isoindole-1,3(2H)-dione2-2-(Methylthio)propyl-1H-isoindole-1,3(2H)-dione 3-(methylthio)propionitrile DL-methionine L-Cysteine iberverin N-benzenesulfonyl-N'-(3-methylsulfanyl-propyl)-ureaN-benzenesulfonyl-N'-(3-methylsulfanyl-propyl)-urea N-(4-chloro-benzenesulfonyl)-N'-(3-methylsulfanyl-propyl)-ureaN-(4-chloro-benzenesulfonyl)-N'-(3-methylsulfanyl-propyl)-urea 3-aminopropranesulfonic acid

📜L-蛋氨酸置于异佛尔酮体系中,用 异丙醇 作为反应溶剂,化学反应 4.0H,以90%的收率获得产物3-(甲基三)丙烯酸呋喃
参考文献:氨基酸的有机催化脱羧是生物胺和酰胺的一种途径
标题:氨基酸的有机催化脱羧是生物胺和酰胺的一种途径
摘要:通过发酵获得或从蛋白质废水解物中回收的氨基酸代表了生产生物基化学品的极好的可再生资源.为了回收碳和氮,我们在此报告了一种化学催化,无金属的氨基酸脱羧方法,从而提供了直接接触伯胺的途径.在羰基化合物存在下,氨基酸被暂时捕获到席夫碱中,从而消除了co 2.可能会更容易进行.在评估了不同类型的醛和酮在低催化剂负载量(<=5Mol%)下的活性后,异佛尔酮在温和条件下被认为是功能强大的有机催化剂.优化后,在150oc下,在2-丙醇中,许多具有中性侧链的氨基酸以28-99%的产率转化.当反应在dmf中进行时,胺很容易发生n甲酰化.该连续反应由氨基酸反应物本身的酸度催化.通过这种方法,许多氨基酸在一锅催化系统中被有效地转化为相应的甲酰胺.
DOI:10.1002/cctc.201900800

专利信息

专利号:WO-2025069039-A1
优先权日:2023-09-28
标题:An in situ process for the preparation of primary amine compounds
发明人：SAMANT RAJARAM; TONGRA MANOJ
权利人:SAMANT RAJARAM; TONGRA MANOJ
摘要:An in situ process for the preparation of primary amine compounds The invention disclosed herein relates to an in situ process for the preparation of primary amine compounds. Particularly, it relates to the preparation of primary amine compounds having general Formula (I). Formula (I) wherein n is 1 to 9 and X is -S, -N- or -O. More particularly, the present invention relates to the preparation of primary amine compounds with high yield and purity which is further used as potent intermediate in the synthesis of therapeutically active isothiocyanates (ITCs).

专利号:US-4086423-A
优先权日:1973-10-12
标题 :Process for cephem synthesis
发明人：FIRESTONE RAYMOND A; RATCLIFFE RONALD W; CHRISTENSEN BURTON G
权利人:MERCK & CO INC
摘要:Cephalosporin antibiotics of the formula: ##STR1## are produced by cycloaddition of a glycine derivative of the formula ##STR2## with a thiazine derivative of the formula ##STR3##

专利号:US-5064962-A
优先权日:1989-02-23
标题:Diaminothiophenes
发明人：WIESENFELDT MATTHIAS; ETZBACH KARL-HEINZ
权利人:BASF AG
摘要:Diaminothiophenes of the formula or tautomers thereof, where R1 and R2 are each hydrogen or together are where T1 is hydrogen, alkyl or phenyl, T2 and T3 are, independently of one another, alkyl or phenyl, or T2 and T3 together with the nitrogen linking them are a heterocyclic radical, R3 is substituted amino and R4 is alkanoyl, benzoyl, cyano, nitro or where T4 is hydrogen, alkyl or phenyl and T5 is the radical of a primary amine or of an active methylene compound, are prepared as described. The present diaminothiophene compound is useful in the synthesis of dyes, crop protection agents and pharmaceuticals.

专利号:WO-2024256496-A1
优先权日:2023-06-14
标题 :[1,2,4]-triazolo[4,3-b]pyridazine derivatives useful as a medicament
发明人：ELIE JONATHAN; GEORGE PASCAL; MIEGE FRÉDÉRIC; MEIJER LAURENT
权利人:PERHA PHARMACEUTICALS
摘要:The present invention relates to a compound of formula (I) or any of its pharmaceutically acceptable salt. The present invention further relates to a synthesis process for manufacturing compound of formula (I) or any of its pharmaceutically acceptable salts, comprising at least a step of reacting a compound of formula (II) with an amine of formula (IV) NHR5R6 for example in a molar ratio ranging from 1 to 20 eq, with respect to the compound of formula (II), in an aprotic solvent or without solvent or else in a protic solvent.

专利号:US-2008176865-A1
优先权日:2005-06-15
标 题:Substituted arylpyrazoles
发明人：BILLEN DENIS; BOYLE JESSICA; CRITCHER DOUGLAS JAMES; GETHIN DAVID MORRIS; HALL KIM THOMAS; KYNE GRAHAM MICHAEL
权利人:PFIZER LTD
摘要:This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.

专利号:US-7968584-B2
优先权日:2005-06-15
标 题:Substituted arylpyrazoles
发明人：BILLEN DENIS; BOYLE JESSICA; CRITCHER DOUGLAS JAMES; GETHIN DAVID MORRIS; HALL KIM THOMAS; KYNE GRAHAM MICHAEL
权利人:PFIZER; PFIZER PROD INC
摘要:This invention relates to a range of 1-aryl-4-cyclopropylpyrazoles in which the cyclopropyl ring is substituted at the angular position, and pharmaceutically acceptable salts and solvates thereof, to compositions comprising such compounds, processes to their synthesis and their use as parasiticides.