CAS: 34801-09-7; N-(2-Aminophenyl)Acetamide

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CAS号552-32-9 2-硝基乙酰苯胺 | CAS号614-76-6 2'-溴乙酰苯胺 | CAS号108-24-7 乙酸酐 | CAS号95-54-5 邻苯二胺(OPD) | CAS号75-36-5 乙酰氯 | CAS号88-74-4 2-硝基苯胺 | CAS号507-09-5 硫代乙酸 | CAS号95635-45-3 N-(4-chloro-2-f... | CAS号7439-89-6 铁粉 | CAS号551-93-9 邻氨基苯乙酮 | CAS号1792-40-1 2-甲基-5-硝基苯并咪唑 | CAS号21354-01-8 N-(2-nitrosophe... | CAS号615-15-6 2-甲基苯并咪唑 | CAS号1454-80-4 2,2'-二氨基联苯 | CAS号29043-48-9 5-氨基-2-甲基苯并咪唑 | CAS号2050-85-3 N,N'-1,2-亚苯基二-乙酰胺 | CAS号18773-93-8 1-乙酰基-1H-苯并三唑 | CAS号134469-07-1 1H-苯并咪唑-2-硫醇 | CAS号75608-87-6 cinnolino[4,3-b... | CAS号75608-90-1 2-chlor°Cinnoli...

📜N-乙酰苯胺置于iron(Iii) Nitrate Nonahydrate,N-羟基邻苯二甲酰亚胺,Palladium On Activated Charcoal,氢气体系中,用 乙醇,1,2-二氯乙烷 作为反应溶剂,化学反应 13.0H,反应生成 邻氨基乙酰苯胺
参考文献:以fe(no 3)3 .9H2O为促进剂和硝基源对苯胺进行区域选择性硝化†
标题:以fe(no 3)3 .9H2O为促进剂和硝基源对苯胺进行区域选择性硝化†
摘要:已经开发出一种有效的fe(no 3)3 .9H2O促进苯胺衍生物的邻位硝化反应.该反应可能通过二氧化氮自由基(no 2)中间体,该中间体是由硝酸铁(iii)的热分解产生的.广泛的底物范围和应用已经证明了使用无毒且廉价的铁试剂的本方法的实用性.
DOI:10.1039/c8Ob00841H

专利信息

专利号:WO-2004092142-A1
优先权日:2003-04-17
标 题:An improved process for manufacture of substituted benzimidazoles
发明人：VYAS KETAN DHANSUKHAL; SINGH DHARMENDRA; NANDAVADEKAR SANJAY; BHISE SANJAY; JADHAV ATUL; DESAI HEMAL
权利人:IPCA LAB LTD; VYAS KETAN DHANSUKHAL; SINGH DHARMENDRA; NANDAVADEKAR SANJAY; BHISE SANJAY; JADHAV ATUL; DESAI HEMAL
摘要:The present invention relates to a process for the production of benzimidazole derivatives comprising providing an amino acetamido benzene derivative; and condensing and cyclising the aminoacetamido benzene derivative in the presence of a base and in the presence of a cyclising agent under conditions effective to form the benzimidazole derivative. The acetamido benzene derivative has the formula (I) wherein R is OMe or OCHF2. The resulting substituted benzimidazoles are key intermediates in the synthesis of H<+>/K<+>-ATPase irreversible inhibitors, most particularly Omeprazole.

专利号:US-2024066023-A1
优先权日:2014-09-17
标题 :Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition
发明人：COX OSVALDO; ZAYAS BEATRIZ
权利人:SISTEMA UNIV ANA G MENDEZ INC
摘要:A synthesis procedure for benzazolo[3,2-a]quinolinium chloride salts and the inclusion of chloro-substituent, amino-substituent, and nitro-substituent resulting in several compounds is provided. The compounds are further used as markers due to their fluorescent properties including in hypoxic environments. Furthermore, anti-cancer screening of two BQS, namely, 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride (ABQ-48: NSC D-763307) and the corresponding 7-benzyl-3-nitrobenzimidazo[3,2-a]quinolinium chloride (NBQ 48: NSC D-763303) are provided.

专利号:US-11786520-B2
优先权日:2014-09-17
标题:Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition
发明人：COX OSVALDO; ZAYAS BEATRIZ
权利人:SISTEMA UNIV ANA G MENDEZ INC
摘要:A synthesis procedure for benzazolo[3,2-a]quinolinium chloride salts and the inclusion of chloro-substituent, amino-substituent, and nitro-substituent resulting in several compounds is provided. The compounds are further used as markers due to their fluorescent properties including in hypoxic environments. Furthermore, anti-cancer screening of two BQS, namely, 7-benzyl-3-aminobenzimidazo[3,2-a]quinolinium chloride (ABQ-48: NSC D-763307) and the corresponding 7-benzyl-3-nitrobenzimidazo[3,2-a]quinolinium chloride (NBQ 48: NSC D-763303) are provided.

专利号:US-9896472-B2
优先权日:2008-09-22
标题 :Protected monomer and method of final deprotection for RNA synthesis
发明人：DELLINGER DOUGLAS J; MYERSON JOEL; SIERZCHALA AGNIESZKA; DELLINGER GERALDINE F; TIMAR ZOLTAN
权利人:AGILENT TECHNOLOGIES INC
摘要:A method of deprotecting a solid support bound polynucleotide includes the step of contacting the polynucleotide with a composition comprising a diamine under conditions sufficient to deprotect the 2′-protected ribonucleotide residue. The solid support bound polynucleotide has at least one 2′-protected ribonucleotide residue, which has the following structure: n nwherein B P is a protected or unprotected heterocycle; R 12 is a protecting group selected from a hydrocarbyl, a substituted hydrocarbyl, an aryl, and a substituted aryl; X is O or S; and PG is a thionocarbamate protecting group.

专利号:CN-111732493-A
优先权日:2017-01-16
标题 :A kind of synthesis technique of aromatic amine compound

专利号:US-8754237-B2
优先权日:2006-02-14
标题:Bifunctional histone deacetylase inhibitors
发明人：BRADNER JAMES ELLIOT; MAZITSCHEK RALPH; TANG WEIPING; SCHREIBER STUART L
权利人:BRADNER JAMES ELLIOT; MAZITSCHEK RALPH; TANG WEIPING; SCHREIBER STUART L; HARVARD COLLEGE; DANA FARBER CANCER INST INC
摘要:In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel bifunctional, trifunctional, or multifunctional compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.