CAS: 3392-11-8; Boc-Trp-Osu
该化合物是一种属于氨基酸衍生物类别的化学化合物.该物质具有锥虫骨干,这是氨基酸基底,因其在蛋白合成中的作用和作为血清素的前体而闻名.1,1-二甲基乙氧基碳基集团的存在表明,它有能够影响其再活动性和溶性的保护性组.2,5-二氧-1-丙基苯基甲基丁基酯细胞表明,该化合物可能具有与循环结构有关的独特特性,有可能影响其生物活动和稳定性.一般来说,这种化合物对制药化学具有潜在用途,特别是在基于丙酸的治疗合成中.具体特性,如溶性,熔点和再活性,将取决于化合物的分子结构和存在的功能组.
- 英文名称Boc-Trp-Osu
- 中文名称BOC-L-色氨酸羟基琥珀酰亚胺酯
- IUPAC名称2,5-dioxopyrrolidin-1-yl (tert-butoxycarbonyl)-L-tryptophanate
- 其它别名Boc-Trp-Osu; 2,5-Dioxopyrrolidin-1-Yl N-(Tert-Butoxycarbonyl)-L-Tryptophanate; Tert-Butyl (S)-(2-((2,5-Dioxo-1-Pyrrolidinyl)Oxy)-1-(1H-Indol-3-Ylmethyl)-2-Oxoethyl)Carbamate; (2,5-Dioxopyrrolidin-1-yl) (2S)-3-(1H-Indol-3-yl)-2-[(2-Methy
- CAS编号3392-11-8
- MFCD编号:MFCD00022756
- EINECS号:222-234-4
- 分子式:C20H23N3O6分子量:401.42
- 产品CID: 2246234
- 产品分类有机原料→分子砌块→芳杂环类化合物→吲哚类化合物
MSDS等安全信息
上下游产品
CAS号6066-82-6 N-羟基琥珀酰亚胺 | CAS号13139-14-5 N-B°C-L-色氨酸 | CAS号107960-02-1 N-(1,2,2,2-四氯乙氧... | CAS号24424-99-5 二碳酸二叔丁酯 | CAS号73-22-3 L-色氨酸 | CAS号55878-81-4 L-Valine,N-[(1,...合成工艺路线路线简述
📜L-色氨酸置于n,N'-二环己基碳二亚胺体系中,用 乙醇,乙腈 作为反应溶剂,化学反应 0.25H,反应生成 Boc-L-色氨酸羟基琥珀酰亚胺酯
参考文献:催化的咪唑鎓盐到抗生物素蛋白的包封:朝着在离子液体中活性的生物杂化催化剂的发展.
标题:催化的咪唑鎓盐到抗生物素蛋白的包封:朝着在离子液体中活性的生物杂化催化剂的发展.
摘要:在此,我们报道了能够催化醛醇缩合反应的生物杂化催化剂的发展.将生物素化的咪唑鎓盐与外消旋或对映体纯的催化阴离子结合使用,使我们能够研究蛋白质内部阴离子催化剂的自适应和协同定位.生物素化催化剂的超分子包封到抗生物素蛋白中,对在离子液体/水混合物中进行的醛醇缩合反应具有非常好的选择性.
DOI:10.1002/chem.201303865
海关参考信息
- 2902200000-苯
2905122000-异丙醇
2905143000-叔丁醇
2912110000-甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-11673912-B2
优先权日:2018-02-16
标 题 :Continuous, solvent-free and non-enzymatic peptide synthesis by reactive extrusion
发明人：YEBOUE YVES; GALLARD BENJAMIN; LE MOIGNE NICOLAS; LAMATY FRÉDÉRIC; MARTINEZ JEAN; METRO THOMAS-XAVIER
权利人:CENTRE NAT RECH SCIENT; UNIV MONTPELLIER; ENSCM; ECOLE DES MINES DALES; ASSOCIATION POUR LA RECH ET LE DEVELOPPEMENT DES METHODES ET PROCESSUS INDUSTRIELS
摘要:A continuous, solvent-free and non-enzymatic method for synthesizing a compound of formula (I): Ra-POLYPEP-Rc (I) wherein: POLYPEP is a poly-amino acid compound, Ra and Rc are as specified, the method including the steps of: a) feeding an extrusion reactor with (1) a compound of formula (II) Ra-PEPNt-Rg (II) wherein; PEPNt is a mono- or a poly-amino acid compound, Ra and Rg are as specified, and (2) a compound of formula (III) H-PEPCt-Rc (III) wherein: PEPCt is a mono- or a poly-amino acid compound, and Rc is as defined in the absence of any solvent, so that the compound of formula (II) and the compound of formula (III) react together for generating a compound of formula (I), and b) collecting the compound of formula (I) from the extrusion reactor.
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:A Facile Synthesis And Crystallographic Analysis Of N-Protected β-Amino Alcohols And Short Peptaibols作者:Sandip V. Jadhav,Anupam Bandyopadhyay,Sushil N. Benke,Sachitanand M. Mali,Hosahudya N. Gopi
摘要:For The Synthesis Of N-Protected β-Amino Alcohols And Peptaibols Using N-Hydroxysuccinimide Active Esters Is Described. Using This Method, Dipeptide, Tripeptide And Pentapeptide Alcohols Were Isolated In High Yields. The Conformations In Crystals Of β-Amino Alcohol, Dipeptide And Tripeptide Alcohols Were Analysed, With A Well-Defined Type Iii β-Turn Being Observed In The Tripeptide Alcohol Crystals
合成参考文献
参考文献:10.1021/jm00027a027
摘要:Ye QZ, Johnson LL, Nordan I, Hupe D, Hupe L. A recombinant human stromelysin catalytic domain identifying tryptophan derivatives as human stromelysin inhibitors. J Med Chem. 1994 Jan 07;37(1):206–9. doi: 10.1021/jm00027a027.
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