CAS: 333-27-7; Methyl Trifluoromethanesulfonate

上下游产品

CAS号114533-01-6 1,1,1-trifluoro... | CAS号2923-28-6 三氟甲烷磺酸银 | CAS号74-88-4 碘甲烷 | CAS号67-56-1 甲醇 | CAS号358-23-6 三氟甲磺酸酐 | CAS号1493-13-6 三氟甲烷磺酸 | CAS号616-38-6 碳酸二甲酯 | CAS号77-78-1 硫酸二甲酯 | CAS号150-78-7 对苯二甲醚 | CAS号68602-57-3 三氟乙酰三氟甲磺酸酯 | CAS号104737-00-0 5-溴-2-甲基-8-硝基-1... | CAS号565-69-5 2-甲基-3-戊酮 | CAS号565-80-0 2,4-二甲基-3-戊酮 | CAS号564-04-5 2,2-二甲基-3-戊酮 | CAS号19078-97-8 2,2-二甲基-3-庚酮 | CAS号460345-16-8 1-己基-3-甲基咪唑三氟甲磺酸盐 | CAS号39021-62-0 1-甲基-1H-咪唑-5-甲醛 | CAS号367522-96-1 1-丁基-1-甲基吡咯三氟甲磺酸盐 | CAS号35900-26-6 4-甲基-5-壬酮 | CAS号4753-75-7 N-甲基糠基胺

1,1,1-Trifluoro-N-Methyl-N-Nitrosomethanesulfonamide置于2,6-二叔丁基-4-甲基吡啶体系中,用 氘代氯仿 作为反应溶剂,以100%的收率获得产物三氟甲烷磺酸甲酯
参考文献:Alkyl Diazonium Ion Pairs And Deamination. Part 45. The Preparation Of Carbonium Ions And Other High-Energy Alkylating Agents Under Mild Conditions
标题:Alkyl Diazonium Ion Pairs And Deamination. Part 45. The Preparation Of Carbonium Ions And Other High-Energy Alkylating Agents Under Mild Conditions
摘要:
DOI:10.1021/ja00219A082

专利信息

专利号:US-2004058888-A1
优先权日:2000-01-13
标题:Methods for synthesis of alpha-d-gal (1~>3) gal-containing oligosaccharides
发明人：BORNAGHI LAURENT; DEKANY GYULA; DRINNAN NICHOLAS BARRY; PAPAGEORGIOU JOHN; WEST MICHAEL LEO
摘要:This invention relates to reagents and methods for synthesis of biologically active di- and tri-saccharides comprising α-D-Gal(1→3)-D-Gal. In particular the invention provides novel reagents, intermediates and processes for the solution or solid phase synthesis of α-D-galactopyranosyl-(1→3)-D-galactose, and derivatives thereof. In one preferred embodiments the invention provides a protected monosaccharide building block of general formula (II): in which R 3 is methoxy or methyl; R 1 is H, benzoyl, pivaloyl, 4-chlorobenzoyl, acetyl, chloroacetyl, levulinoyl, 4-methylbenzoyl, benzyl, 3,4-methylenedioxybenzyl, 4-methoxybenzyl, 4-chlorobenzyl, 4-acetamidobenzyl, or 4-azidobenzyl; and R 2 is H, Fmoc, benzoyl, pivaloyl, 4-chlorobenzoyl, acetyl, chloroacetyl, levulinoyl, 4-methylbenzoyl, benzyl, 3,4-methylenedioxybenzyl, 4-methoxybenzyl, 4 -chlorobenzyl, 4-acetamidobenzyl, or 4-azidobenzyl.

专利号:US-2021107859-A1
优先权日:2018-04-06
标题 :A process for the synthesis of carbon labeled organic compounds
发明人：AUDISIO DAVIDE; CANTAT THIBAULT; DESTRO GIANLUCA
权利人:COMMISSARIAT ENERGIE ATOMIQUE
摘要:A process for the synthesis of a carbon labeled organic compound containing a carbon labeled carboxyl group is described. A method of using carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; a process for manufacturing labeled pharmaceuticals and agrochemicals comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure; and a process for producing tracers comprising synthesis of carbon labeled organic compounds containing a carbon labeled carboxyl group according to the present disclosure are also described.

专利号:US-4910310-A
优先权日:1988-10-03
标 题:Synthesis of N-substituted 1,5-dideoxy-1,5-imino-L-fucitol derivatives
发明人：CAMPBELL ARTHUR L; BEHLING JAMES R; BABIAK KEVIN A; NG JOHN S; MUELLER RICHARD A; FLEET GEORGE W J
权利人:SEARLE & CO
摘要:Novel intermediates and method for the chemical synthesis of N-substituted 1,5-dideoxy-1,5-imino-L-fucitol derivatives are provided. A preferred intermediate is 1,5-dideoxy-1,5-imino-3, 4-O-isopropylidene-L-fucitol which is used to prepare the HIV inhibitor 1,5-dideoxy-1,5-imino-[N-ω-methyl caproate]-L-fucitol. These compounds are prepared in a short synthesis from the known compound 2,3-O-isopropylidene-D-lyxono-1,4-lactone or in a multi-step synthesis from D-galactose.

专利号:US-10053406-B2
优先权日:2015-10-23
标题 :Synthesis of honokiol
发明人：JARACZ STANISLAV; KOZLOWSKI MARISA; EUN LEE YOUNG; KIM SUN MIN
权利人:COLGATE PALMOLIVE CO; UNIV PENNSYLVANIA
摘要:Disclosed herein are improved methods for the synthesis of honokiol, as well as methods for the synthesis of 3,3′-di-tert-butyl-5,5′-dimethyl-[1,1′-biphenyl]-2,4′-diol, 3′,5-dimethyl-[1,1′-biphenyl]-2,4′-diol, and 2,4′-dimethoxy-3′,5-dimethyl-1,1′-biphenyl, 3,3′,5,5′-tetra-tert-butyl-[1,1′-biphenyl]-2,4′-diol, and certain tetrasubstituted bisphenols, and uses therefor.

专利号:US-7829032-B2
优先权日:2007-01-23
标题 :Fully-automated microfluidic system for the synthesis of radiolabeled biomarkers for positron emission tomography
发明人：VAN DAM ROBERT MICHAEL; BALL CARROLL EDWARD; ELIZAROV ARKADIJ M; KOLB HARTMUTH C
权利人:SIEMENS MEDICAL SOLUTIONS
摘要:The present application relates to microfluidic devices and related technologies, and to chemical processes using such devices. More specifically, the application discloses a fully automated synthesis of radioactive compounds for imaging, such as by positron emission tomography (PET), in a fast, efficient and compact manner. In particular, this application describe an automated, stand-alone, microfluidic instrument for the multi-step chemical synthesis of radiopharmaceuticals, such as probes for PET and a method of using such instruments.

专利号:US-2025188046-A1
优先权日:2023-12-08
标题:Ultrafast flow synthesis of functionalized sulfonyl fluorides and subsequent sufex connections via lithiated chemistry
发明人：KIM DONG-PYO; KANG JI-HO
权利人:POSTECH RES & BUSINESS DEV FOUND
摘要:Disclosed are ultrafast flow synthesis of functionalized sulfonyl fluorides and subsequent SuFEx connections via lithiated chemistry. In detail, a method of synthesizing an ortho-functionalized benzenesulfonyl fluoride derivative, the method comprises (a) reacting a benzenesulfonyl fluoride derivative represented by structural formula 1 with an organolithium represented by structural formula 2, thus synthesizing an intermediate represented by structural formula 3 in reaction scheme 1 and (b) reacting the intermediate with an electrophile, thus synthesizing a compound represented by structural formula 4 or a compound represented by structural formula 4′. The present disclosure enables the synthesis of several functionalized sulfonyl fluorides within a few seconds under mild temperature conditions in addition to the chemistry of Sulfonyl Fluoride Exchange (SuFEx), which is a next-generation click chemistry, so that sulfonyl fluoride, the main reactant of the SuFEx reaction, can be efficiently secured.