CAS: 21867-64-1; 1-Propylpiperazine

相似化合物

64262-23-3 5610-49-1 71888-55-6

上下游产品

4-ethoxycarbonylpiperazine -4-(1-propyl)piperazine1-(3,4-dichlorophenyl)acetyl-4-(1-propyl)piperazine 8-Fluoro-3-methyl-6-oxo-9-(4-propyl-piperazin-1-yl)-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid N-(2-Allyloxy-phenyl)-N-[2-hydroxy-3-(4-propyl-piperazin-1-yl)-propyl]-methanesulfonamide; hydr°Chloride N-(2-Allyloxy-phenyl)-N-[2-hydroxy-3-(4-propyl-piperazin-1-yl)-propyl]-4-methyl-benzenesulfonamide; hydr°Chloride

Phenyl(4-Propylpiperazin-1-yl)Methanone置于盐酸体系中,化学反应 5.0H,以74%的收率获得1-丙基哌嗪
参考文献:Kafka,Stanislav; Cermak,Jan; Novak,Tomas,Collection Of Czechoslovak Chemical Communications,1985,Vol. 50,# 5,P. 1201-1211
标题:Kafka,Stanislav; Cermak,Jan; Novak,Tomas,Collection Of Czechoslovak Chemical Communications,1985,Vol. 50,# 5,P. 1201-1211

专利信息

专利号:US-6136984-A
优先权日:1996-04-22
标 题 :Solid phase and combinatorial synthesis of substituted thiophenes and of arrays of substituted thiophenes
发明人：DOERWALD FLORENCIO ZARAGOZA
权利人:NOVO NORDISK AS
摘要:A solid phase method for the synthesis of a plurality of differently substituted thiophenes with a wide variety of side-chain substituents as compounds of potential therapeutic interest is disclosed. The thiophenes are prepared by acylation of a substrate-bound primary or secondary amine with cyanoacetic acid and reaction of the resulting cyanoacetamide with an isothiocyanate in the presence of a base. Alkylation with an appropriate alkyl halide, followed by Thorpe-Ziegier-cyclization yields differently substituted, support-bound 3-aminothiophenes. These may be screened on the substrate or cleaved from the substrate and then screened in solution. Alternatively, the resin-bound 3-amino thiophenes or the synthetic intermediates can be subjected to further synthetic transformations (N-acylation, reduction) on the support, which permits the preparation of further therapeutically interesting compounds. The efficient synthesis of a wide variety of thiophenes using automated synthesis technology of the present method makes these compounds attractive candidates for the generation and rapid screening of diverse thiophene-based libraries. The method disclosed here provides an easy and fast access to highly diverse heterocyclic compounds of therapeutic interest, amenable to automatization.

专利号:US-9481649-B2
优先权日:2009-08-24
标题 :Synthesis of a neurostimulative piperazine
发明人：VENKATRAMAN SRIPATHY; MAHMOOD SYED; MOBELE BINGIDIMI I; LAPINA OLGA; VERCOE KELLIE; LI YING; SALSBURY JONATHAN; MCLAWS MARK
权利人:NEURALSTEM INC
摘要:The invention describes an improved synthesis for piperazine derivatized with nicotinic acid and a benzyl moiety. The product compounds are useful for treatment of neurological conditions.

专利号:US-7902295-B2
优先权日:2004-08-05
标 题 :Single step synthesis of functional multi-block polymer
发明人：BOERNER PETER W; GRAVES DANIEL; HALL JAMES E; ICEMAN BRENT
权利人:FIRESTONE POLYMERS LLC
摘要:The inventive composition includes a block copolymer which includes four blocks and has the following block arrangement: B-S-B-S. The two polymer blocks B comprise conjugated diene monomer constitutional units; and the two polymer blocks S comprise vinyl aromatic hydrocarbon monomer constitutional units. The invention also includes methods of making such inventive compositions as well as asphalt compositions and/or thermoplastic elastomers which include such block copolymer.

专利号:US-9108954-B2
优先权日:2010-02-02
标 题:Synthesis process of dasatinib and intermediate thereof
发明人：YAN RONG; YANG HAO; HOU WEN; XU YONGXIANG
权利人:YAN RONG; YANG HAO; HOU WEN; XU YONGXIANG; NAN JING CAVENDISH BIO ENGINEERING TECHNOLOGY CO LTD
摘要:Synthesis process of dasatinib is disclosed, which includes the step of reacting the compound of formula I with that of formula II to obtain the compound of formula III. Also disclosed is the compound of formula III which is used as an intermediate for synthesizing dasatinib. The substituents of R1, R2, R3 or R4 in formulae I, II or III are defined as in the description.

专利号:US-8357344-B2
优先权日:2009-03-10
标 题 :Gas deacidizing method using an absorbent solution with vaporization and/or purification of a fraction of the regenerated absorbent solution
发明人：BOUILLON PIERRE-ANTOINE; JACQUIN MARC
权利人:INST FRANCAIS DU PETROLE; BOUILLON PIERRE-ANTOINE; JACQUIN MARC
摘要:The gaseous effluent to be treated is contacted in column C 1 with an absorbent solution selected for its property of forming two separable phases when it is heated. The regenerated absorbent solution is separated into two phases in drum B 1 ; a fraction rich in water and a fraction rich in reactive compounds. n Separation allows to optimize the operations performed on the regenerated absorbent solution. On the one hand, separation allows to carry out vaporization, through reboiler R 1 , of a fraction of the absorbent solution, preferably containing a limited reactive compound concentration in relation to the absorbent solution, thus limiting their degradation. On the other hand, separation of the phases allows to reduce the amount of solution to be treated in order to remove the non-regeneratable salts and thus to reduce the costs linked with their elimination. Finally, separation allows to eliminate the degradation products by carrying out a specific and suitable purification for each phase. n The method can be applied to combustion fumes decarbonation and to natural gas or synthesis gas deacidizing.

专利号:US-2006030671-A1
优先权日:2004-08-05
标题:Single step synthesis of functional multi-block polymer