CAS: 2008-58-4; 2,6-Dichlorobenzamide

上下游产品

CAS号25185-95-9 2,6-二氯苯甲醛肟 | CAS号1194-65-6 2,6-二氯苯腈 | CAS号83-38-5 2,6-二氯苯甲醛 | CAS号19393-92-1 1-溴-2,6-二氯苯 | CAS号3019-71-4 三氯乙酰基异氰酸酯 | CAS号144-55-8 碳酸氢钠 | CAS号4659-45-4 2,6-二氯苯甲酰氯 | CAS号6575-28-6 (E)-2,6-dichlor... | CAS号3714-77-0 (Z)-2,6-DICHLOR... | CAS号118-69-4 2,6-二氯甲苯 | CAS号608-31-1 2,6-二氯苯胺 | CAS号35377-49-2 2,6-dichloroben... | CAS号35409-97-3 除幼脲 | CAS号35367-09-0 2,6-dichloro-N-... | CAS号1194-65-6 2,6-二氯苯腈 | CAS号116800-83-0 METHYL N-(2,6-D... | CAS号67048-91-3 5-(2,6-dichloro... | CAS号92207-23-3 2,6-dichloro-N-...

2,6-二氯苯甲酰氯置于ammonium Hydroxide体系中,用 二氯甲烷 用作溶剂,化学反应 3.5H,反应生成2,6-二氯苯甲酰胺
参考文献:含有酰肼-Hydr和羧酰胺基团的新型1,3-噻唑衍生物的合成,抗肿瘤活性和作用机理
标题:含有酰肼-Hydr和羧酰胺基团的新型1,3-噻唑衍生物的合成,抗肿瘤活性和作用机理
摘要:合成了一系列新颖的2,4,5-三取代1,3,3-噻唑衍生物,其中包括酰肼-肼,以及包括46个化合物t的羧酰胺部分,并评估了它们在体外对五种人类癌细胞系的抗肿瘤活性.18种标题化合物t对mcf-7,Hepg2,Bgc-823,Hela和a549细胞系的抑制活性高于5-Fu.尤其是,T1,T26和t38表现出最佳的ic 50细胞毒性活性分别针对mcf-7,Bcg-823和hepg2细胞系的2.21μg/ Ml,1.67μg/ Ml和1.11μg/ Ml值.这些结果表明,1,3-噻唑,酰肼-Hydr和羧酰胺部分的组合对细胞毒性活性非常有利.此外,流式细胞仪分析表明,化合物t1和t38可以诱导hepg2细胞凋亡,并证实t38通过s细胞周期停滞诱导了细胞凋亡的诱导.
Doi:10.1016/j.Bmcl.2016.05.059

专利信息

专利号:CN-102477452-A
优先权日:2010-11-22
标题:Enzymatic Synthesis of a Surfactant

专利号:US-5354905-A
优先权日:1992-10-23
标 题 :N-alkoxymethyl benzamide derivative and manufacturing method therefor, and manufacturing method for benzamide derivative using this N-alkoxymethyl benzamide derivative
发明人：SATO YOSHIHIRO; KOISO AKIHIRO; ASADA TOHRU; MIURA YASUHISA; KIKUCHI YASUO; HARIYA YASUAKI
权利人:YASHIMA KAGAKU KOGYO KK
摘要:An N-alkoxymethyl benzamide derivative represented by Formula (I); (I) (In the formula, reference X indicates a halogen atom, references Y1 and Y2 indicate hydrogen atoms or halogen atoms, and may be identical or different, and reference R indicates a lower alkyl group.) and a manufacturing method for this N-alkoxymethyl benzamide derivative in which a substituted benzamide and an alpha -haloacetal are reacted. Furthermore, a manufacturing method for benzamide derivatives in which the N-alkoxymethyl benzamide derivative represented by Formula (I) above and benzene or a derivative thereof are reacted, and a benzamide derivative is produced. The N-alkoxymethyl benzamide derivative of the present invention is a novel compound, and possesses utility as an intermediate in the manufacturing of oxazoline derivatives which possess insecticidal and anti-mite activity, and as a starting material for the synthesis of various organic compounds and the like.

专利号:US-5096710-A
优先权日:1989-05-27
标 题 :Poison bait for control of noxious insects
发明人：MINAGAWA FUMIYASU; KOHAMA TAKUJI; KAWADA HITOSHI; SHINJO GORO; MAEDA KAZUYUKI
权利人:SUMITOMO CHEMICAL CO
摘要:A bait composition in a tablet form, which comprises as the essential components (a) at least one insect-growth controlling agent chosen from (a-1) insect juvenile hormone-like compounds and (a-2) insect chitin-synthesis inhibitors, (b) dextrin and (c) a plant oil in an amount of not more than 10% by weight to the total bait composition.

专利号:US-9701686-B2
优先权日:2009-12-04
标题:Tricyclopyrazole derivatives
发明人：DISINGRINI TERESA; MANTEGANI SERGIO; VARASI MARIO
权利人:NERVIANO MEDICAL SCIENCES SRL
摘要:Compounds which are tricyclopyrazole derivatives or pharmaceutically acceptable salts thereof, their preparation process and pharmaceutical compositions comprising them are disclosed; these compounds are useful in the treatment of diseases caused by and/or associated with an altered protein kinase activity such as cancer, viral infection, prevention of AIDS development in HIV-infected individuals, cell proliferative disorders, autoimmune and neurodegenerative disorders; also disclosed is a process under Solid Phase Synthesis conditions for preparing the compounds of the invention and chemical libraries comprising a plurality of them.