CAS: 811-62-1; Chloro(Dimethyl)Phosphine

该化合物是有机磷磷原子与两个甲基组和一个氯原子相连的化合物,其分子式为C2H7ClP,典型的是一种无色至黄色的液体,有刺鼻的气味.该化合物以其反应性而著称,特别是由于磷-氯联系的存在,它可以在水中进行水解,导致磷衍生物的形成.氯二甲基磷在有机溶剂中溶解,并用于各种用途,包括作为有机合成中的试剂和用于生产磷离心剂以协调化学.然而,必须谨慎地处理该物质,因为它可能有毒,并对人类健康和环境构成危险.适当的安全措施,包括使用个人防护设备和适当的通风,在与该化学品合作时至关重要.

结构式图片

上下游产品

methylene chloride methyldichlorophosphane (dimethylamino)dimethylphosphine tetramethyldiphosphanedimethylphosphinothioic chloride benzyldimethylphosphine oxide

合成工艺路线路线简述

    📜1,1,2,2-四甲基-二膦置于二苯基氯化膦体系中,化学反应 2.0H,以81%的收率获得产物氯(二甲基)膦
    参考文献:核磁共振和核磁共振分析
    标题:核磁共振和核磁共振分析
    摘要:通过使四有机二膦与氯二苯基或二氯苯基膦反应,制备了一系列的二正烷基和正烷基芳基氯膦,并通过31 P和13 C NMR光谱进行了表征.
    DOI:10.1016/0022-328X(86)80520-4

    专利信息


    专利号:US-2025197431-A1
    优先权日:2023-12-15
    标 题:Methods and systems for forming a layer comprising silicon and composition and synthesis of silicon precursor
    发明人:ROMERO PATRICIO EDUARDO; VERVUURT RENÉ HENRICUS JOZEF; DEZELAH CHARLES; PORE VILJAMI J
    权利人:ASM IP HOLDING BV
    摘要:Disclosed are methods and systems for forming a silicon-containing layer on a substrate. Further disclosed are composition and synthesis of silicon-containing precursor. The methods for forming a silicon-containing layer comprise executing a plurality of deposition cycles. A deposition cycle comprises a first precursor pulse that comprises exposing the substrate to a first precursor. The first precursor comprises a molecule comprising a P—Si bond. A deposition cycle further comprises a plasma pulse that comprises exposing the substrate to a plasma treatment. The plasma treatment comprises generating a plasma.

    专利号:US-3720736-A
    优先权日:1970-03-17
    标 题 :Process for the synthesis of dihydrocarbonphosphinates
    发明人:QUICK J; VENEZKY D
    权利人:US NAVY
    摘要:A PROCESS FOR THE SYNTHESIS OF A DIHYDROCARBONPHOSPHINATE WHEREIN A DIHYDROCARBONAHALOPHOSPHINE IS OXIDIZED IN THE PRESENCE OF A DIHYDROCARBON SULFOXIDE, SUCH AS DIMETHYLSULFOXIDE, AND THE REACTION MIXTURE THEREOF IS REACTED WITH AN APPROPRIATE ALCOHOL TO FORM THE DESIRED ESTER.

    专利号:US-7759471-B2
    优先权日:2005-10-31
    标题 :Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection
    发明人:DELLINGER DOUGLAS J; TIMAR ZOLTAN; SIERZCHALA AGNIESZKA; DELLINGER GERALDINE; CARUTHERS MARVIN H
    权利人:AGILENT TECHNOLOGIES INC; UNIV COLORADO
    摘要:Nucleotide monomers, polynucleotides, methods of making each, methods of deprotecting each, and the like are disclosed herein.

    专利号:US-9885035-B2
    优先权日:2002-10-30
    标 题 :Method for the synthesis of a bifunctional complex
    发明人:FRANCH THOMAS; GOULIAEV ALEX HAAHR
    权利人:NUEVOLUTION AS
    摘要:Disclosed is a method for obtaining a bifunctional complex comprising a display molecule part and a coding part, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is reacted at the chemical reaction site with one or more reactants, and provided with respective tag(s) identifying the reactant(s) at the priming site is using one or more enzymes.

    专利号:US-7301041-B2
    优先权日:2002-02-14
    标 题:Bi-functional metallocenes, preparation process and use in the labeling or biological molecules
    发明人:CHAIX-BAUVAIS CAROLE; MOUSTROU CORINNE; NAVARRO AUDE-EMMANUELLE; BRISSET HUGUES; GARNIER FRANCIS; MANDRAND BERNARD; SPINELLI NICOLAS
    权利人:BIO MERIEUX
    摘要:The invention relates to bi-functionalised metallocenes of general formula (I) where Me=a transition metal, preferably chosen from Fe, Ru and Os, Y and Z, when identical are selected from —(CH 2 ) n —O—, (CH 2 )—O—[(CH 2 ) 2 —O] P — and —(CH 2 ) q —CONH—(CH 2 ) r —O—, or Y=—(CH 2 ) S —NH— and Z=—(CH 2 ) t —COO—, n =a whole number from 3 to 6 inclusive, p=a whole number from 1 to 4 inclusive, q=a whole number from 0 to 2 inclusive, r=a whole number from 0 to 2 inclusive, s=a whole number from 2 to 5 inclusive, t=a whole number from 3 to 6 inclusive, R and R′=H atoms or are protective groups used in oligonucleotide and peptide synthesis, where at least one of R or R′ is protective group used in oligonucleotide and peptide synthesis and R and R′ are as defined below: (i) when Z and Y are selected from (CH 2 ) n —O—, —(CH 2 )—O—[(CH 2 ) 2 —O] p — and —(CH 2 ) q —CONH—(CH 2 ) r —O—, then R and R′ are protective groups used in oligonucleotide synthesis and R is a group which can leave a free OH group after deprotection, preferably a photolabile group such as monomethroxythoxytrityl, dimethoxytrityl, t-butyldimethylsilyl, acetyl or trifluroacetyl, and R′ is a phosphorylated group which can react with a free OH, preferably a phosphodiester, phosphoramidite or H-phosphonate and (ii) when Y=—(CH 2 ) s —NH— and Z=—(CH 2 ) t —COO—, then R is a protective group used in the synthesis of peptides and is an amino-protecting group, preferably 9-fluorenyloxycarbonyl, t-butoxycarbonyl or benzyloxycarbonyl and R′=H. The above is applied in marking.

    专利号:US-2007100136-A1
    优先权日:2005-10-31
    标题:Monomer compositions for the synthesis of RNA, methods of synthesis, and methods of deprotection

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Kimura, T., Science of Synthesis Knowledge Updates, (2016) 2, 448.
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