CAS: 6926-58-5; 4,4-Dimethyl-3-Thiosemicarbazide

该化合物是一种有机化合物,其特点是硫酰胺结构,具有硫酰胺功能组,该物质一般是白色至白晶状固体,由于存在单水合物形式,在水中溶解;其分子式反映氮原子中存在两个附着的甲基组,有助于其独特的化学特性;该化合物因其在医药化学中的潜在应用而闻名,特别是在合成各种生物活性分子方面,并可能展示抗微生物和抗硫酸盐活动;此外,该物质可作为其他硫酰氨衍生物的前体;安全数据表明,与许多硫酰氨酸盐制剂一样,应对该物质时,应注意其潜在的毒性和刺激性.建议采用适当的实验室做法,包括使用个人防护设备.

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相似化合物

6610-29-3 6938-68-7 6972-05-0

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上下游产品

CAS号16420-13-6 二甲氨基一硫代甲酰氯 | CAS号5397-03-5 肼基二硫代甲酸甲酯 | CAS号124-40-3 二甲胺 | CAS号4007-01-6 S-(N,N-二甲基硫代氨甲酰... | CAS号3735-92-0 甲基二甲二硫氨基甲酸 | CAS号97-74-5 一硫化四甲基秋兰姆 | CAS号137-26-8 二硫化四甲基秋兰姆 | CAS号57477-93-7 (4-bromophenyl)... | CAS号2810-66-4 1,3,4-Thiadiazo... | CAS号87587-01-7 3-[1-(1-hydroxy... | CAS号63300-99-2 1,1-dimethyl-3-...

合成工艺路线路线简述

  • 合成目标产物 4,4-Dimethyl-3-Thiosemicarbazide 主要起始原料 Dimethylthiocarbamoyl Chloride
  • (文献来源)合成步骤主要原料 Dimethylthiocarbamoyl Chloride
📜一硫化四甲基秋兰姆置于肼体系中,化学反应生成 4,4-二甲基-3-氨基硫脲单水合物
参考文献:Jensen,K.A. Et Al.,Acta Chemica Scandinavica (1947),1968,Vol. 22,P. 1-50
标题:Jensen,K.A. Et Al.,Acta Chemica Scandinavica (1947),1968,Vol. 22,P. 1-50

海关参考信息

专利信息


专利号:CN-109897071-A
优先权日:2019-03-28
标 题 :A kind of platinum complex with 2-pyridinecarboxaldehyde thiosemicarbazide as ligand and its synthesis method and application

专利号:CN-109651414-A
优先权日:2019-01-16
标 题:A kind of indium compound with 2,6-diacetylpyridine thiosemicarbazide as ligand and its synthesis method and application

专利号:CN-112341479-A
优先权日:2020-11-13
标 题:A kind of synthesis method of binuclear zinc complex and its application

专利号:CN-112250697-A
优先权日:2020-10-23
标 题 :A kind of gold complex with o-vanillin thiosemicarbazide as ligand and synthesis method thereof

专利号:CN-111925398-B
优先权日:2020-09-22
标题 :A kind of FTO small molecule inhibitor palladium complex and its synthesis method

专利号:CN-111961092-A
优先权日:2020-09-22
标 题:A kind of iron complex with 5-chloro-2-hydroxybenzaldehyde thiosemicarbazide as ligand and its synthesis method and application

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📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


参考文献:10.1186/1471-2407-14-629
摘要:Shen H, Zhu H, Song M, Tian Y, Huang Y, Zheng H, Cao R, Lin J, Bi Z, Zhong W. A selenosemicarbazone complex with copper efficiently down-regulates the 90-kDa heat shock protein HSP90AA1 and its client proteins in cancer cells. BMC Cancer. 2014 Aug 29;14():629.
参考文献:10.1007/s11164-023-04975-y
摘要:Wang Y, Wei S, Miao L, Lü C, An Y. A new 1,3,4-thiadiazole-based ESIPT probe for detection of Hcy/Cys and GSH by two-channel fluorescent procedure and its potential applications. Res Chem Intermed. 2023 Feb 10;49(5):2191–208. doi: 10.1007/s11164-023-04975-y.
参考文献:10.1007/s00775-018-1596-y
摘要:Xie F, Cai H, Peng F. Anti-prostate cancer activity of 8-hydroxyquinoline-2-carboxaldehyde-thiosemicarbazide copper complexes in vivo by bioluminescence imaging. JBIC Journal of Biological Inorganic Chemistry. 2018 Jul 13;23(6):949–56. doi: 10.1007/s00775-018-1596-y.
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