CAS: 62224-16-2; Methyl 4-Bromothiophene-2-Carboxylate

上下游产品

CAS号16694-18-1 4-溴噻吩-2-甲酸 | CAS号67-56-1 甲醇 | CAS号18791-75-8 4-溴-2-噻吩甲醛 | CAS号6324-10-3 4,5-二溴噻吩-2-甲酸 | CAS号58777-65-4 4-溴-2-噻吩羰酰氯 | CAS号709648-80-6 4-(4,4,5,5-四甲基-... | CAS号31862-80-3 4-溴-5-硝基噻吩-2-羧酸甲酯 | CAS号666721-41-1 methyl 4-(4-nit... | CAS号851340-17-5 4-(2-Carboxythi... | CAS号5118-05-8 methyl 4-methox...

📜4,5-二溴噻吩-2-甲酸置于氯化亚砜,溶剂黄146,锌体系中,用 水 作为反应溶剂,化学反应 2.92H,反应生成 4-溴噻吩-2-甲酸甲酯
参考文献:Binder,Dieter; Prager,Bernhard C.; Noe,Christian R.,Journal Of Chemical Research,Miniprint,1981,# 5,P. 1801-1824
标题:Binder,Dieter; Prager,Bernhard C.; Noe,Christian R.,Journal Of Chemical Research,Miniprint,1981,# 5,P. 1801-1824

专利信息

专利号:US-8178559-B2
优先权日:2004-12-30
标 题:Organic compounds
发明人：BREITENSTEIN WERNER; EHARA TAKERU; EHRHARDT CLAUS; GROSCHE PHILIPP; HITOMI YUKO; IWAKI YUKI; KANAZAWA TAKANORI; KONISHI KAZUHIDE; MAIBAUM JUERGEN KLAUS; MASUYA KEIICHI; IWASAKI ATSUKO; OSTERMANN NILS; SUZUKI MASAKI; TOYAO ATSUSHI; YOKOKAWA FUMIAKI
权利人:BREITENSTEIN WERNER; EHARA TAKERU; EHRHARDT CLAUS; GROSCHE PHILIPP; HITOMI YUKO; IWAKI YUKI; KANAZAWA TAKANORI; KONISHI KAZUHIDE; MAIBAUM JUERGEN KLAUS; MASUYA KEIICHI; IWASAKI ATSUKO; OSTERMANN NILS; SUZUKI MASAKI; TOYAO ATSUSHI; YOKOKAWA FUMIAKI; NOVARTIS AG
摘要:3,4-substituted piperidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on activity of renin; the use of a compound of that class in the treatment of a disease that depends on activity of renin; pharmaceutical formulations comprising a 3,4-substituted piperidine compound, and/or a method of treatment comprising administering a 3,4substituted piperidine compound, a method for the manufacture of a 3,4-substituted piperidine compound, and novel intermediates and partial steps for their synthesis are disclosed. The 3,4-disubstituted piperidine compounds have the formula (I), wherein the symbols have the meanings defined in the specification.

专利号:WO-2022012456-A1
优先权日:2020-07-17
标题:Novel heterocyclic compounds as bet inhibitors
发明人：FANG HAIQUAN; LUO XINFENG; SHU TIANBO; ZHANG JIBING; WU XIANQIANG; ZHU HUI; WANG YING
权利人:CHENGDU EASTON BIOPHARMACEUTICALS CO LTD
摘要:Provided are heterocyclic compounds of formula (I) as bromodomain and extraterminal (BET) inhibitors, pharmaceutical compositions comprising the compounds, their synthesis and their use for treating diseases and conditions wherein inhibition of one or more BET bromodomains provides a benefit.

专利号:CN-116023359-B
优先权日:2022-12-29
标题:A kind of synthesis method of aminothiophene compound and aminothiophene compound

专利号:CN-116023359-A
优先权日:2022-12-29
标 题 :Synthesis method of aminothiophene compound and aminothiophene compound