CAS: 59473-45-9; 1-(Chloromethyl)-2-Iodobenzene

上下游产品

2-iodobenzyl alcohol 1-(2-iodophenyl)-N,N-dimethylmethanamine -peroxidBis-2-jod-phenylacetyl-peroxid phosphorus pentachloride 2-(pyrrolidin-1-ylmethyl)phenyl iodide 2-(piperidin-1-ylmethyl)phenyl iodide 2-(N-morpholylmethyl)-iodobenzene 1-[(2-iodophenyl)methyl]-4-methylpiperazine

2-碘苄醇置于三苯基膦体系中,用 四氯化碳 作为反应溶剂,化学反应 24.0H,以87%的收率获得产物邻碘氯苄
参考文献:芳基自由基与烯醇化物离子反应速率常数的测定
标题:芳基自由基与烯醇化物离子反应速率常数的测定
摘要:发现通过中间苯基型自由基在系链双键处的分子内攻击,O-(ω-烯基)芳基自由基的闭环速率 (Kc) 为 4.2 x 108 S-1(对于 1•) 和 7.6x107 S−1(对于 8•),都是 6-Exo-Trig 过程,9.6 x 109 S−1 对于 3• 的 5-Exo-Trig 过程.这些自由基的 Kc 速率常数根据已知的 H 原子提取速率 (Kh) 进行校准.自由基钟前体 1 与阴离子 Phs− 和 (Eto)2Po−置于25 oc 下在 Me2So 中的光刺激 Srn1 反应提供了这些亲核试剂 (Ky) 添加到中间体 1•(3.2 x 108 和 2.5 x 109M−1)的速率s−1,分别).相比之下,酮烯醇化物离子与前体 1 的类似反应没有进行预期的 Srn1 过程;相反,有利于消除反应.相似地,自由基时钟前体 3 或 8 与烯醇化物离子的反应失败.然而,研究 9-蒽基 (11•)
DOI:10.1002/1099-0690(200104)2001:7<1323::Aid-Ejoc1323>3.0.Co;2-C

专利信息

专利号:US-7999090-B2
优先权日:2000-07-07
标 题:Fungal cell wall synthesis gene
发明人：TSUKAHARA KAPPEI; HATA KATSURA; SAGANE KOJI; NAKAMOTO KAZUTAKA; TSUCHIYA MAMIKO; WATANABE NAOAKI; OHBA FUMINORI; TSUKADA ITARU; UEDA NORIHIRO; TANAKA KEIGO; KAI JUNKO
权利人:EISAI R&D MAN CO LTD
摘要:The present invention provides isolated DNA encoding a GWT1 protein having activity to confer resistance of a fungus against a compound of formula Ia, and wherein a defect of a function of the GWT1 protein leads to a decrease in the amount of a glycosylphosphatidylinositol (GPI)-anchored protein in the cell wall of a fungus.

专利号:JP-2001031618-A
优先权日:1999-07-21
标 题:Synthesis of cycloheptadienone derivative

专利号:US-10202326-B2
优先权日:2014-10-21
标题:Polyprenylated phloroglucinol compounds as potent P-glycoprotein inducers
发明人：BHARATE SANDIP; KUMAR AJAY; BHARATE JAIDEEP; JOSHI PRASHANT; WANI ABUBAKAR; MUDUDUDDLA RAMESH; SHARMA ROHIT; VISHWAKARMA RAM
权利人:COUNCIL SCIENT IND RES
摘要:The present invention relates to the polyprenylated phloroglucinol compounds of formulae I and II. The present invention also provides synthesis and p-glycoprotein induction activity of the alkyl- and acyl-polyprenylated phloroglucinol compounds. Further, use of the compounds as p-glycoprotein inducers and methods of treatment of Alzheimer's disease using compounds of the invention are also provided.

专利号:WO-2008150439-A1
优先权日:2007-06-01
标 题 :Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use