CAS: 55747-45-0; Ethyl 2-Acetyl-5-(1,3-Dioxoisoindolin-2-yl)Pentanoate

该化合物是一种有机化合物,其特征是其酯功能组和硫酰胺混合物,该化合物一般是白色的,白色的固体或晶状物质,其结构复杂,包括乙酸乙酰乙酸基骨,有助于其反应和有机合成中的潜在应用;该硫酰二酰胺组的存在可提高其在各种化学反应中的效用,特别是在形成氨和其他衍生物时的效用;乙酰2-(3-N-甲基)乙酰丙基乙酸酯经常用于药用化学和药物合成中的一种中间体;其溶性可变性,但一般是有机溶剂中的溶性,适合各种实验室应用;在处理和储存时,应参考安全数据,如任何化学物质,以确保采取适当的预防措施.

结构式图片

物理性质

MSDS等安全信息

上下游产品

2-(3-bromopropyl)isoindole-1,3-dione sodium ethyl acetylacetate enolate ethyl acetoacetate N-(3-chloropropyl)phthalimide2-ethoxycarbonyl-3-(2-phthalimidoethyl)-5-methoxyindole 2-phenylhydrazono-5-phthalimido-pentanoic acid ethyl ester

合成工艺路线路线简述

    📜N-(3-氯苯基)邻苯二甲酰亚胺置于potassium Carbonate,Sodium Iodide体系中,用 丙酮 作为反应溶剂,化学反应 268.0H,反应生成 2-(3-N-邻苯二甲酰亚胺丙基)乙酰乙酸乙酯
    参考文献:Prabhakar; Kumar,N. Vasanth; Reddy,M. Ravikanth,Organic Process Research And Development,1999,Vol. 3,# 3,P. 155-160
    标题:Prabhakar; Kumar,N. Vasanth; Reddy,M. Ravikanth,Organic Process Research And Development,1999,Vol. 3,# 3,P. 155-160

    海关参考信息

    专利信息


    专利号:DE-68925135-T2
    优先权日:1988-02-25
    标题 :Process for the total synthesis of an indole structure compound class of the tryptamine type, in particular melatonin or N-acetyl-5-methoxytryptamine with high purity and solubility, usable in AIDS therapy

    专利号:US-2005113397-A1
    优先权日:2002-01-31
    标题:Imidazo[1,2-a]pyridine derivative
    发明人：TAKEMURA MAKOTO; TAKAHASHI HISASHI; KAWAKAMI KATSUHIRO; TAKESHITA HIROSHI; KIMURA YOUICHI; WATANABE JUN; SUGIMOTO YUICHI; KITAMURA AKIHIRO; NAKAJIMA RYOHEI; KANAI KAZUO; FUJISAWA TETSUNORI
    摘要:A compound reprsented by the following formula (I), its salts or nsolvates thereof capable of specifically or selectively expressig an antifungal activity in a broad spectrum based on the novel mechanism thereof of 1,6-β-glucan synthesis inhibition, and an antifungal agent containing any of them.

    专利号:IT-1230493-B
    优先权日:1988-09-08
    标 题:TOTAL SYNTHESIS PROCEDURE, FOR OBTAINING A CATEGORY OF INDOLIC STRUCTURAL PRODUCTS OF THE TRIPTAMIN TYPE IN PARTICULAR MELATONIN OR N-VINEGARS 5-METHOXYTYRIPTAMINE WITH HIGH DEGREE OF PURITY AND EASILY FLEXIBLE USEABLE. FOR THE TREATMENT OF SYNDROMES FROM

    专利号:EP-0330625-B1
    优先权日:1988-02-25
    标题 :Total synthesis method for making an indole structure derivative product class, of the triptamine type, in particular, melatonin or N-acetyl-5-methoxytriptamine type, having a high purity degree and easily soluble, for therapeutic use against acquired immuno-deficiency syndromes

    专利号:CN-113968809-A
    优先权日:2021-11-05
    标题 :A kind of chemical synthesis method of melatonin

    专利号:EP-0330625-A2
    优先权日:1988-02-25
    标 题:Total synthesis method for making an indole structure derivative product class, of the triptamine type, in particular, melatonin or N-acetyl-5-methoxytriptamine type, having a high purity degree and easily soluble, for therapeutic use against acquired immuno-deficiency syndromes

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    合成参考文献


    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2010) 2, 30.
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