CAS: 469-39-6; (2Ar,3R,5As,5Bs,7As,8S,9S,11Ar,12As)-2A,5A,8-Trimethyl-3-((R)-6-Methyl-5-Methyleneheptan-2-yl)Tetradecahydro-1H,12H-Cyclopenta[a]Cyclopropa[e]Phenanthren-9-Ol

上下游产品

cycloeucalenone 24-methylenecycloartanol Methanesulfonic acid (R)-2-isopropyl-5-[(3S,4S,9S,10R,13R,14S,17R)-4,13,14-trimethyl-3-(tetrahydro-pyran-2-yloxy)-tetradecahydro-cyclopropa[9,10]cyclopenta[a]phenanthren-17-yl]-hexyl ester cyclohomonervilolphthalic acid mono-(24-methylene-9β,19-cyclo-31-nor-lanostan-3β-yl ester) 3β-benzoyloxy-24-methylene-9β,19-cyclo-31-nor-lanostane 24-methylenecycloartanol cycloartanol

📜Cycloeucalenone置于lithium Aluminium Tetrahydride体系中,用 四氢呋喃 作为反应溶剂,化学反应 3.0H,以7 Mg的收率获得产物3-Epicycloeucalenol
参考文献:Cycloartane Triterpenes From The Fruit Peel Of Musa Sapientum
标题:Cycloartane Triterpenes From The Fruit Peel Of Musa Sapientum
摘要:
DOI:10.1016/s0031-9422(98)80081-2

专利信息

专利号:US-7906710-B2
优先权日:2001-01-05
标 题:Transgenic plants containing altered levels of steroid compounds
发明人：KARUNANANDAA BALASULOJINI; POST-BEITTENMILLER MARTHA; VENKATRAMESH MYLAVARAPU; KISHORE GANESH M; THORNE GREGORY M; LEDEAUX JOHN R
权利人:MONSANTO CO
摘要:Disclosed are constructs comprising sequences encoding 3-hydroxy-3methylglutaryl-Coenzyme A reductase and at least one other sterol synthesis pathway enzyme. Also disclosed are methods for using such constructs to alter sterol production and content in cells, plants, seeds and storage organs of plants. Also provided are oils and compositions containing altered sterol levels produced by use of the disclosed constructs. Novel nucleotide sequences useful in the alteration of sterol production are also provided. Also provided are cells, plants, seeds and storage organs of plants comprising sequences encoding 3-hydroxy-3methylglutaryl-Coenzyme A reductase, at least one other sterol synthesis pathway enzyme and at least one tocopherol synthesis enzyme.

专利号:US-3686235-A
优先权日:1969-10-14
标 题:Class of liquid crystals
发明人：NICHOLAS HAROLD J; KNAPP FURN F JR
权利人:HAROLD J NICHOLAS; FURN F KNAPP JR
摘要:THE CHEMICAL SYNTHESIS AND ISOLATION FROM NATURAL SOURCES OF A NEW CLASS OF CHOLESTERIC AND SMECTIC LIQUID CRYSTALS ARE DESCRIBED. THESE CONSIST OF VARIOUS FATTY ACID ESTERS OF TETRACYLIC TRIERTENES INCLUDING MEMBERS OF THE CLASS OF 9,19-CYCLOPROPANE TRITERPENES. THESE TRITERPENES INCLUDE 9,19-CYCLOLANOST-24-EN-3B-OL(CYCLOARTENOL), 4A,14A,24B-TRIMETHYL-9,19-CYCLOCHOLESTAN-3B-OL, 24E-METHYL-9,19-CYCLOLANOSTAN-3B-OL(24E-METHYL CYCLOARTANOL) AND 24-DIHYDRO LANOSTEROL AND ALL CHEMICALLY RELATED PRODUCTS.

专利号:US-2003157583-A1
优先权日:2001-12-17
标 题:Methods for determining squalene synthase activity
发明人：STEVENS DONNA; WANG XIAO-ZHUO; RICE JOHN; NYE BETH; BROADWELL DAVID; GLASSBROOK NORMAN; SEVALA VEERESH; CRAWFORD JOHN; STEWART SANDY
摘要:The cloning of a truncated Arabidopsis gene expressing squalene synthase, as well as the expression and purification of the squalene synthase, are described. Also described herein is a fluorescent assay using squalene synthase that is amenable to high-throughout use, particularly for studying the regulation of isoprenoid synthesis and identifying squalene synthase inhibitors and promoters. As the formation of squalene is stoichiometric with the depletion of NADPH, the activity of squalene synthase can be evaluated by following the NADPH concentration over time. Squalene synthase activity is determined by combining FPP, NADPH, squalene synthase and a magnesium ion cofactor to form a reaction mixture under conditions suitable for squalene formation, optionally in the presence of a compound being analyzed for its ability to inhibit or promote squalene synthase. The concentration of NADPH over time is determined by subjecting the reaction mixture to UV light and detecting fluorescent light emission.