CAS: 22038-86-4; (R)-1-(4-Methoxyphenyl)Ethan-1-Amine

上下游产品

1-(4-methoxyphenyl)ethanamine N'-(1-(4-methoxyphenyl)ethylidene)benzohydrazide methylmagnesium bromide (R)-2-(4-Methoxy-phenyl)-4-phenyl-oxazolidine (R)-(+)-NN-dimethyl-1-p-methoxyphenylethylamine l-N-α-Methyl-p-methoxybenzyl-N,N-dimethylamin -2,5-dihydro-6H-pyran-6-carboxamideN-(R)-1-(p-methoxyphenyl)ethyl-2,5-dihydro-6H-pyran-6-carboxamide (R)-(2-(4-methoxyphenyl)-propylidene)-carbamic acid methyl ester

(S)-(-)-1-(4-甲氧基苯)乙胺置于氢气体系中,用 甲苯 用作溶剂,90.0 °C,10.0 Kpa 条件下,反应 12.0H,反应生成(R)-(+)-1-(4-甲氧基苯)乙胺
参考文献:碱式盐对负载型钯催化剂的选择性消旋和伯胺的动态动力学拆分的改性†
标题:碱式盐对负载型钯催化剂的选择性消旋和伯胺的动态动力学拆分的改性†
摘要:通过初期湿润浸渍法,用各种碱金属盐修饰了负载的钯纳米粒子(pdnps).研究了盐对(S)-1-苯基乙胺外消旋作用的pd催化剂的催化活性和选择性行为的影响.碱金属盐的存在可以大大提高pd催化剂的选择性,而不会显着降低催化活性.这种修饰方法适用于负载在各种支持物(​​例如微/中氧化硅和活性炭)上的pdnp.结合固定化的脂肪酶(novozyme 435),该催化剂体系可以有效催化1-苯基乙胺的动态动力学拆分(dkr),产率和对映选择性分别高达97%和99%.
Doi:10.1039/c3Cy00535F

专利信息

专利号:US-8084630-B2
优先权日:2007-05-31
标 题 :Process for the synthesis of ramelteon and its intermediates
发明人：KANSAL VINOD KUMAR; MISTRY DHIRENKUMAR N; VASOYA SANJAY L; RAFILOVICH MICHAL; MOHA-LERMAN ELENA BEN; LIFSHITZ-LIRON REVITAL
权利人:KANSAL VINOD KUMAR; MISTRY DHIRENKUMAR N; VASOYA SANJAY L; RAFILOVICH MICHAL; MOHA-LERMAN ELENA BEN; LIFSHITZ-LIRON REVITAL; TEVA PHARMA
摘要:The present invention provides processes and intermediates for the synthesis of ramelteon.

专利号:US-2009281176-A1
优先权日:2007-11-01
标题:Process for the synthesis of ramelteon and its intermediates
发明人：KANSAL VINOD KUMAR; MISTRY DHIRENKUMAR N; VASOYA SANJAY L; PATEL RAKESH; JADAV ARPAN M
权利人:KANSAL VINOD KUMAR; MISTRY DHIRENKUMAR N; VASOYA SANJAY L; PATEL RAKESH; JADAV ARPAN M
摘要:A process for the preparation of ramelteon and intermediates useful in the process. The process suitable for industrial scale provides increased yield and/or greater purity with fewer process steps.

专利号:US-5300437-A
优先权日:1989-06-22
标 题 :Enantiomeric enrichment and stereoselective synthesis of chiral amines
发明人：STIRLING DAVID I; MATCHAM GEORGE W; ZEITLIN ANDREW L
权利人:CELGENE CORP
摘要:Amines in which the amino group is on a secondary carbon atom which is chirally substituted can be enantiomerically enriched by the action of an omega-amino acid transaminase which has the property of preferentially converting one of the two chiral forms to a ketone. The process also can be used to stereoselectively synthesize one chiral form from ketones substantially to the exclusion of the other.

专利号:US-10736911-B2
优先权日:2015-12-29
标题 :Use of a DHODH inhibitor in combination with an inhibitor of pyrimidine salvage
发明人：DEANS RICHARD; OKESLI AYSE; MORGENS DAVID; KHOSLA CHAITAN; BASSIK MICHAEL C
权利人:UNIV LELAND STANFORD JUNIOR
摘要:Compounds and methods are provided for the treatment of pathogenic virus infections or cancer. The formulations combine an inhibitor of de novo pyrimidine synthesis, and an inhibitor of a pyrimidine salvage pathway enzyme.

专利号:WO-2023002323-A1
优先权日:2021-07-19
标 题 :Synthesis of substituted tricyclic amides and analogues thereof

专利号:US-2024327419-A1
优先权日:2021-07-19
标 题 :Synthesis of substituted tricyclic amides and analogues thereof
发明人：MASON JEREMY; PALLERLA MAHESH; PAMULAPATI GANAPATI REDDY
权利人:ARBUTUS BIOPHARMA CORP
摘要:The present disclosure includes synthetic methods for preparing certain substituted tricyclic amides, which can be used to treat, ameliorate, and/or prevent hepatitis B virus (HBV) and/or hepatitis D virus (HDV) infections in a subject.