CAS: 19564-40-0; 3-(O-Tolyl)Propanal

上下游产品

CAS号201230-82-2 carbon monoxide | CAS号611-15-4 2-甲基苯乙烯 | CAS号14902-36-4 3-(邻甲苯基)丙-1-醇 | CAS号615-37-2 2-碘甲苯 | CAS号107-18-6 烯丙醇 | CAS号95-46-5 2-溴甲苯 | CAS号2373-76-4 邻甲基肉桂酸 | CAS号104750-61-0 3-(邻甲苯基)丙酸乙酯 | CAS号122-51-0 原甲酸三乙酯 | CAS号898789-19-0 4'-METHOXY-3-(2... | CAS号93614-78-9 邻甲基肉桂醛

📜3-(O-甲苯基)丙-1-醇置于pyridinium Chlorochromate体系中,用 四氢呋喃 用作溶剂,化学反应 16.0H,以0.303 G的收率获得3-邻甲苯-丙醛
参考文献:分子内,中断的 Homo-Nazarov 级联双环化成角(杂)芳基稠合多环
标题:分子内,中断的 Homo-Nazarov 级联双环化成角(杂)芳基稠合多环
摘要:连接到(杂)芳烃上的烯基环丙基酮很容易经历催化,分子内中断的同-纳扎罗夫级联双环化,形成 6,6,6-,6,5,6-,6,6,5-,6,6,6,5-和 6,6,5,6 融合的角度架构.该方法用于 (+/-)-1-Oxoferruginol 的简明全合成,这是一种具有生物活性的枞树烷二萜.
Doi:10.1002/chem.202201368

专利信息

专利号:US-4131623-A
优先权日:1969-07-08
标 题:Synthesis of aldehydes and products of such synthesis
发明人：MEYERS ALBERT I
权利人:UNIV LOUISIANA STATE
摘要:The disclosure describes the production of complex aliphatic, unsaturated and cycloalkane aldehydes utilizing heterocyclic ring compounds, such as oxazines, particularly dihydro-1,3-oxazines. The oxazines are treated with an alkali metal-alkane compound, such as butyl lithium in the presence of an organic solvent at subzero temperature to form an anion of the oxazine. This anion is then alkylated in the anhydrous reaction mixture by introduction of a suitable halide, epoxide or ketone while still at a subzero temperature and mixture is permitted to warm up to room temperature, following which the reaction mixture is acidified, as with hydrochloric acid to pH 2 to 3, extracted and then made basic, as with caustic alkali with cooling. n The reaction mixture is then extracted, as with ether, to produce after evaporation the alkylated dihydro-1,3-oxazine. n The alkylated dihydro-1,3-oxazine is then reacted with an alkali metal or sodium borohydride or borodeuteride or borotritide, with cooling to subzero temperatures at about a neutral pH and then transferred into a basic aqueous environment following extraction of the aqueous layer with an organic solvent, such as ether, to give a tetrahydro-1,3-oxazine. This compound may then be converted to the aldehyde desired by steam distillation or by hydrolysis in the presence of a dilute or weak acid, such as hydrochloric or oxalic acid. The aldehydes may then be extracted. n These aldehydes are useful as components or intermediates in flavoring or perfumes, in insect attractants and repellants, and in pharmaceuticals.

专利号:US-11225655-B2
优先权日:2010-04-16
标题:Bi-functional complexes and methods for making and using such complexes
发明人：GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK
权利人:GOULIAEV ALEX HAAHR; FRANCH THOMAS; GODSKESEN MICHAEL ANDERS; JENSEN KIM BIRKEBAEK; NUEVOLUTION AS
摘要:The present invention is directed to a method for the synthesis of a bi-functional complex comprising a molecule part and an identifier oligonucleotide part identifying the molecule part. A part of the synthesis method according to the present invention is preferably conducted in one or more organic solvents when a nascent bi-functional complex comprising an optionally protected tag or oligonucleotide identifier is linked to a solid support, and another part of the synthesis method is preferably conducted under conditions suitable for enzymatic addition of an oligonucleotide tag to a nascent bi-functional complex in solution.