CAS: 1936-18-1; Salutaridine

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      专利号:US-8450365-B2
      优先权日:2009-05-12
      标 题 :Efficient synthesis of galanthamine
      发明人:MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ
      权利人:MAGNUS PHILIP D; FAUBER BEN; SANE NEERAJ; UNIV TEXAS
      摘要:The present invention relates to methods for the synthesis of galanthamine, morphine, intermediates, salts and derivatives thereof. In preferred embodiments, the invention relates to methods for improving the efficiency and overall yield of said morphine, morphine related derivatives and intermediates thereof. In further embodiments, the invention relates to methods for improving the efficiency and overall yield of galanthamine and intermediates thereof.

      专利号:US-3894027-A
      优先权日:1973-07-31
      标 题:Resolution of racemic reticuline and racemization of its enantiomers
      发明人:SOHAR PAUL; SCHOENEWALDT ERWIN F
      权利人:MERCK & CO INC
      摘要:Racemic reticuline is resolved by forming a crystalline diastereomeric acid salt with a mandelic acid enantiomer. The reticuline enantiomers are racemized by treatment with a reduced noble metal or noble metal oxide catalyst. (-)-Reticuline is a valuable intermediate useful in the synthesis of thebaine, and (+)-reticuline is useful as a precursor of pallidine, sinoacutine, coreximine, and the berberine alkaloids.

      专利号:US-8293927-B2
      优先权日:2009-05-12
      标 题 :Efficient synthesis of morphine and codeine

      专利号:DE-112010001980-T5
      优先权日:2009-05-12
      标题 :Synthesis of morphine and related derivatives

      专利号:CA-2761287-A1
      优先权日:2009-05-12
      标题 :Synthesis of morphine and related derivatives

      专利号:US-2010292466-A1
      优先权日:2009-05-12
      标题 :Efficient Synthesis Of Galanthamine

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      摘要:US EPA; Estimation Program Interface (EPI) Suite. Ver. 4.1. Nov, 2012. Available from, as of July 25,2016:
      摘要:Franke C et al; Chemosphere 29: 1501-14 (1994)
      摘要:
      参考文献:10.1080/14786410310001608154
      摘要:Sari A, Gray AI, Sariyar * G. A new Dehydroaporphine Alkaloid fromPapaver Fugax. Natural Product Research. 2004 Jun;18(3):265–8. doi: 10.1080/14786410310001608154.
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