专利号:US-2010160244-A1 优先权日:2004-09-02 标 题 :Methods and compositions for enhancing collagen, proteoglycan, and glutathione synthesis in the skin 发明人:NIMNI MARCEL; HAN BO 权利人:NIMNI MARCEL; HAN BO 摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids or hydrolyzed whey protein; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid or a lipoic acid analogue or derivative. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.
专利号:US-6849701-B2 优先权日:2001-03-02 标 题:Droplet polymerization method for synthesis of molecularly imprinted polymers 发明人:NORTON TUCKER 权利人:DU PONT 摘要:A droplet polymerization process is provided to create efficacious molecularly imprinted polymers (MIPs). Such imprinted polymers have increased surface area for adsorptive or catalytic reactions. This method provides for monomer-template interactions in the absence of a suspending medium, thereby permitting formation of MIPs with increased template selectivity and substantial processing advantages. The process is particularly useful for separating isoflavones from soy whey.
专利号:US-7202398-B2 优先权日:2002-08-16 标 题 :Chalcone isomerase 发明人:MCGONIGLE BRIAN 权利人:DU PONT 摘要:An isolated nucleic acid fragment encoding a chalcone isomerase is disclosed. Also of concern is the synthesis of a recombinant DNA construct encoding all or a portion of the chalcone isomerase, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels of the chalcone isomerase in a transformed host cell.
专利号:US-2002198349-A1 优先权日:2001-03-02 标 题:Droplet polymerization method for synthesis of molecularly imprinted polymers
专利号:CA-2389904-A1 优先权日:2001-03-02 标 题:Droplet polymerization method for synthesis of molecularly imprinted polymers
专利号:JP-2004018576-A 优先权日:2001-03-02 标 题 :Droplet polymerization method for the synthesis of molecularly imprinted polymers
1: Handa CL, de Lima FS, Guelfi MF, Georgetti SR, Ida EI. Multi-response optimisation of the extraction solvent system for phenolics and antioxidant activities from fermented soy flour using a simplex-centroid design. Food Chem. 2016 Apr 15;197(Pt A):175-84. doi: 10.1016/j.foodchem.2015.10.124. Epub 2015 Nov 11. doi: 10.1016/j.foodchem.2015.08.115. Epub 2015 Sep 3.
合成参考文献
参考文献:10.1021/jf00044a016 摘要:Wang H, Murphy PA. Isoflavone Content in Commercial Soybean Foods. J. Agric. Food Chem. 1994 Aug;42(8):1666–73. doi: 10.1021/jf00044a016.