CAS: 118-58-1; Benzyl 2-Hydroxybenzoate

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69-72-7 78646-17-0 94-18-8

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CAS号100-39-0 溴化苄 | CAS号69-72-7 水杨酸 | CAS号100-51-6 苯甲醇 | CAS号118-61-6 水杨酸乙酯 | CAS号100-44-7 氯化苄 | CAS号36340-89-3 N,N-diisopropyl... | CAS号14389-87-8 Benzyl 2-(benzy... | CAS号87-20-7 水杨酸异戊酯 | CAS号119-36-8 水杨酸甲酯 | CAS号54-21-7 水杨酸钠 | CAS号487-54-7 2-羟基马尿酸 | CAS号221287-88-3 1-((2-苄氧基氧羰基)苯基... | CAS号221287-92-9 1-[[[2-N-(5-硝基噻... | CAS号221287-90-7 1-(2-羧苯基)-2,3,4... | CAS号78718-25-9 Benzoic acid,2-... | CAS号52160-84-6 2-[2-(4-chlorop... | CAS号52602-17-2 benzyl 2-acetyl...

2-乙酰氧基苯甲酸苄酯置于4-二甲氨基吡啶体系中,用 二氯甲烷 用作溶剂,化学反应 12.0H,反应生成柳酸苄酯
参考文献:吸出α-氨基醇(sarpogrelate M1)
标题:吸出α-氨基醇(sarpogrelate M1)
摘要:α-氨基醇(沙格雷酯 M1)的抽吸已在各种一般酯化条件下进行.在大多数情况下,所需的阿司匹林酯以低产率获得,并带有意想不到的副产物,其形成主要源自叔 α-氨基的化学性质.在对这些方法进行系统分析后,使用结合水杨酸酯形成和乙酰化的两步方法制备了抽吸沙格雷酯 M1.
Doi:10.3390/molecules21091126

专利信息

专利号:US-7576234-B2
优先权日:2002-05-15
标题 :Synthesis of 2-alkyl amino acids
发明人：CHORGHADE MUKUND S; GURJAR MUKUND K; MOHAPATRA DEBENDRA K
权利人:GENZYME CORP
摘要:Non-natural amino acids such as 2-alkylated amino acids allow for the synthesis of a wider variety of peptidal and non-peptidal pharmaceutically active agents. A method of preparing a 2-alkyl amino acid involves a Michael-type addition of a nucleophile to a dialkyl 2-methylidenylpropan-1,3-dioate and the conversion of a ester moiety into an amino moiety. The present invention also discloses a method of preparing a class of iron chelating agents related to desferrithiocin, all of which contain a thiazoline ring. In this method, an aryl nitrile or imidate is condensed with cysteine, a 2-alkyl cysteine, or a cysteine ester.

专利号:US-5925622-A
优先权日:1998-07-13
标题:Synthesis of aryl glucuronide of 2-hydroxy-N- (5-nitro-2-thiazolyl) benzamide, and pharmaceutical compositions comprising same
发明人：ROSSIGNOL JEAN-FRANCOIS; AYERS MARC S
权利人:ROMARK LAB LC
摘要:An aryl glucuronide of 2-hydroxy-N-(5-nitro-2-thiazolyl)benzamide, preferably an O-aryl glucuronide, as well as methods for the convenient synthesis of these aryl glucuronides, highly stable and low toxicity pharmaceutical composition containing these aryl glucuronides, and methods for use of these pharmaceutical compositions, for example, for treatment of inflammation, infections, etc.

专利号:US-7598291-B2
优先权日:2004-09-02
标题 :Methods and compositions for enhancing collagen and proteoglycan synthesis in the skin
发明人：NIMNI MARCEL; HAN BO
权利人:NIMNI MARCEL; HAN BO
摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid, a lipoic acid analogue or derivative, a bioflavonoid, a constituent of ginkgo, or an isoflavone. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

专利号:US-2010160244-A1
优先权日:2004-09-02
标 题 :Methods and compositions for enhancing collagen, proteoglycan, and glutathione synthesis in the skin
发明人：NIMNI MARCEL; HAN BO
权利人:NIMNI MARCEL; HAN BO
摘要:A composition for application to the skin can stimulate the in vivo synthesis of collagen and proteoglycans and improve the appearance of the skin, increasing its elasticity and fullness. In general, a composition according to the present invention comprises: (1) an antioxidant compound in a quantity sufficient to enhance collagen synthesis in the skin; (2) an organic penetrant in which the antioxidant compound is soluble in a sufficient quantity that a concentration of the antioxidant compound sufficient to enhance collagen synthesis can be applied topically and penetrate the skin; (3) a mixture of essential amino acids or hydrolyzed whey protein; (4) a supplemental source of sulfur; and (5) a topical pharmaceutically acceptable carrier. The antioxidant compound can be lipoic acid or a lipoic acid analogue or derivative. The organic penetrant is preferably benzyl alcohol. Other ingredients, such as esters of tocopherol and ascorbic acid, can be included.

专利号:US-8440608-B2
优先权日:2004-08-06
标题:Beta-substituted tetrandropyrana (on) s and method for the synthesis and the use thereof
发明人：MANE JEAN; CHANOT JEAN-JACQUES; SCHROEDER MARTIN
权利人:MANE JEAN; CHANOT JEAN-JACQUES; SCHROEDER MARTIN; MANE FILS V
摘要:The invention relates, in particular to a tetrahydropyran(on) compound which is substituted in position beta with respect to a cycle oxygen of formula (I), wherein a substituent R is a linear alkyl radical in C2:C10 including, (CH 3 ) 2 CH— or C 6 H 5 —(CH 2 ) m —, with m=0 or 1, or formula (II), wherein A is —CH 2 — or —CO—, in the form of an odorant and to a method for the synthesis thereof by reducing oxo-ester. The use of the inventive compound in composition such as perfumery compositions in the ordinary sense of the term i.e. topic, in particular cosmetic compositions and care products.

专利号:US-4880775-A
优先权日:1989-02-01
标题 :Poly-alkylated benzodioxin musk compositions
发明人：CHRISTENSON PHILIP A; DRAKE BRIAN; RIKER PAUL J
权利人:BASF K & F CORP
摘要:The present invention relates to novel poly-alkylated benzodioxin compounds possessing a musk-like aroma which are useful as fragrance materials. The compounds of the invention have the formula: where R1 to R4 are hydrogen or lower alkyl (C1 to C5), provided that the compound has no more than 18 carbon atoms. The invention provides for synthesis of a novel phenolic intermediate and synthesis of the compounds of the invention. The invention also provides fragrance compositions which utilize the compounds of the invention to modify, enhance, or impart a musk-like aroma to perfume compositions, colognes and perfumed articles.