CAS: 943518-63-6; Benzamide, N-[(4-Hydroxyphenyl)Methyl]-3,4-Dimethoxy

上下游产品

CAS号122898-67-3 伊托必利

📜4-羟基苄胺,藜芦酸置于co(Dmgh)(Dmgh2)Cl2,[ir(Df(Cf3)Ppy)2(Dtbbpy)](Pf6),三苯基膦体系中,用 二氯甲烷 作为反应溶剂,以66%的收率获得产物n-(4-羟基苄基)-3.4-二甲氧基苯甲酰胺
参考文献:通过光氧化还原/钴肟催化反应生成氧鏻离子用于批量和连续流动的可扩展酰胺和肽合成
标题:通过光氧化还原/钴肟催化反应生成氧鏻离子用于批量和连续流动的可扩展酰胺和肽合成
摘要:报道了一种用于合成酰胺和肽的光催化方法.钴肟和光氧化还原催化剂之间的协同作用通过使用 Pph 3作为温和的有机还原剂去除了 H2O 元素.脱氧方法与克级肽合成兼容,适用于肽片段缩合和spps,可在有机合成和药物生产中找到应用.
DOI:10.1002/anie.202112668

专利信息

专利号:US-2009177008-A1
优先权日:2005-12-28
标题:Novel process for synthesis of itopride and its novel intermediate n-(4-hydroxybenzyl)- 3,4-dimethoxybenzamide
发明人：KHAMAR BAKULESH MAFATLAL; MODI INDRAVADAN AMBALAL; VENKATRAMAN JAYARAMAN; RAVI PONNAIAH; NORI DIVAKARA SOMAYAJULU; GAJULA MADHUSUDANA RAO; RENUGADEVI GURUSAMY; SHASHIKALA KUNJARU N; RUDRAMUNI SANTOSH M
权利人:CADILA PHARMACEUTICALS LTD
摘要:The present invention relates to a novel and improved process for the preparation of N-[4-[2-(dimethylamino)ethoxy]benzyl]-3,4-dimethoxybenzamide—known as Itopride, via a novel intermediate N-(4Ëœhydroxybenzyl)-3,4-dimethoxybenzamide.

专利号:WO-2007074386-A3
优先权日:2005-12-28
标题:A novel process for synthesis of itopride and it’s novel intermediate-n-(4-hydroxybenzyl)-3,4-dimethoxybenzamide

专利号:WO-2007074386-B1
优先权日:2005-12-28
标 题 :A novel process for synthesis of itopride and it’s novel intermediate-n-(4-hydroxybenzyl)-3,4-dimethoxybenzamide

专利号:WO-2007074386-A9
优先权日:2005-12-28
标 题 :A novel process for synthesis of itopride and it’s novel intermediate-n-(4-hydroxybenzyl)-3,4-dimethoxybenzamide

专利号:WO-2007074386-A2
优先权日:2005-12-28
标题 :A novel process for synthesis of itopride and it’s novel intermediate-n-(4-hydroxybenzyl)-3,4-dimethoxybenzamide