CAS: 79995-67-8; (2R,3R)-3,5-Dihydroxy-2-(3-Hydroxy-4-Methoxyphenyl)-7-Methoxychroman-4-One
该化合物是天然产生的化学化合物,被归类为氟虫素,主要来自以其药性著称的蓝虫植物,其稳定性和功效可能受温度和光照射等因素的影响.Blumetain B研究继续探索其潜在的治疗应用,特别是在传统医学中,它可以在治疗各种疾病方面发挥作用.
- 英文名称(2R,3R)-3,5-Dihydroxy-2-(3-Hydroxy-4-Methoxyphenyl)-7-Methoxychroman-4-One
- 中文名称艾纳香素 B
- IUPAC名称(2R,3R)-3,5-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-methoxychroman-4-one
- 其它别名3,5-Dihydroxy-2-(3-Hydroxy-4-Methoxyphenyl)-7-Methoxy-2,3-Dihydro-4H-1-Benzopyran-4-One; 4H-1-Benzopyran-4-One, 2,3-Dihydro-3,5-Dihydroxy-2-(3-Hydroxy-4-Methox Yphenyl)-7-Methoxy-, (2R,3R)-; (2R,3R)-3,5-Dihydroxy-2-(3-Hydroxy-4-
- CAS编号79995-67-8
- FDA UNII编号:TU9SEK9386
- 分子式:C17H16O7分子量:332.31
- 产品CID: 1793762
- 产品分类天然产物 → 黄酮类化合物
物理性质
MSDS等安全信息
上下游产品
diazomethane taxifolin合成工艺路线路线简述
- 480-18-2 + 153666-25-2 = 79995-67-8 + 649552-43-2 + 649552-41-0 + 37971-67-8 + 649552-45-4 + 74628-44-7 + 80453-44-7 + 649552-44-3
反应条件:1.1 Solvents: Diethyl Ether,Benzene; 9 D,4 °C
标题:Methylation Of Dihydroquercetin Acetates: Synthesis Of 5-O-Methyldihydroquercetin
作者:Kiehlmann,Eberhard; Et Al
参考文献:Journal Of Natural Products 日期:2003 卷标:66(12) 页码:1562-1566
📜重氮甲烷,花旗松素 以 乙醚,苯 作为反应溶剂,化学反应 1.5H,以28%的收率获得产物李属素
参考文献:Structure-activity Relationship For (+)-Taxifolin Isolated From Silymarin As An Inhibitor Of Amyloid β Aggregation
标题:Structure-activity Relationship For (+)-Taxifolin Isolated From Silymarin As An Inhibitor Of Amyloid β Aggregation
摘要:Silymarin,The Seed Extract Of Silybium Marianum,Has Preventive Effects Against Alzheimer'S Disease-Like Pathogenesis In Vivo. We Isolated (+)-Taxifolin (4) From Silymarin As An Inhibitor Of Aggregation Of The 42-Residue Amyloid Beta-Protein. Structure-Activity Relationship Studies Revealed The 3',4'-Dihydroxyl Groups To Be Critical To The Anti-Aggregative Ability,Whereas The 7-Hydroxyl Group And The Stereochemistry At Positions 2 And 3 Were Not Important.
DOI:10.1271/bbb.120925
海关参考信息
- 2902600000-乙苯
2905122000-异丙醇
2905310000-1,2-乙二醇
2905320000-1,2-丙二醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
参考标题:Methylation Of Dihydroquercetin Acetates: Synthesis Of 5-O-Methyldihydroquercetin作者:Eberhard Kiehlmann,Peter W. Slade |发布日期:2003.12.1
摘要:The Major Products Of Methylation Of Dihydroquercetin (1, Dhq) With Diazomethane Have Been Identified As 7-O-Methyldhq (9), 7,3'-Di-0-Methyldhq (10), 7,4'-Di-O-Methyldhq (11), And 7,3',4'-Tri-O-Methyldhq (2). With Dhq 3,7,3',4'-Tetraacetate (6), Dhq 3,5,3',4'-Tetraacetate (5), Dhq 3,3',4'-Triacetate (7), Dhq 7,3',4'Triacetate (8), And Dhq 3-Acetate (4) The Same Reaction Affords Mainly 5-O-Methyldhq 3,7,3',4'-Tetraacetate (15), 7-O-Methyldhq 3,5,3',4'-Tetraacetate (13), 7-O-Methyldhq 3,3',4'-Triacetate (14), 5-O-Methyldhq 7,3',4'Triacetate (25), And 7-O-Methyldhq 3-Acetate (12), Respectively. The Methylation Of 8 Is Accompanied By Intermolecular Acetyl Migration From Phenolic Oxygen To The Hydroxy Group Of The Heterocyclic Ring. 5-O-Methyldhq (28) Is Accessible By Deacetylation Of 25. 5,7-Di-O-Methyldhq (29), Four Known Methyl Ethers, 13 New And Three Known Methyl Ether Acetates Of Dhq, And Six New Isomers With 2,3-Cis Stereochemistry Were Spectroscopically Identified.
合成参考文献
参考文献:10.1016/j.sajb.2011.09.010
摘要:Yagi S, Chrétien F, Duval RE, Fontanay S, Maldini M, Piacente S, Henry M, Chapleur Y, Laurain-Mattar D. Antibacterial activity, cytotoxicity and chemical constituents of Hydnora johannis roots. South African Journal of Botany. 2012 Jan;78():228–34. doi: 10.1016/j.sajb.2011.09.010.
参考文献:10.3987/com-08-s(f)79
摘要:Ishibashi M, Ohtsuki T, Hiraka T, Kikuchi H, Koyano T, Kowithayakorn T, Sakai T. Flavonoids from Eupatorium odoratum with Death Receptor 5 Promoter Enhancing Activity. HETEROCYCLES. 2009;77(2):1379. doi: 10.3987/com-08-s(f)79.
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