CAS: 7244-02-2; (Ethylenedithio)Diaceticacid

相似化合物

5244-34-8 123-93-3 627-04-3

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CAS号68-11-1 硫代乙醇酸(TGA) | CAS号106-93-4 1,2-二溴乙烷 | CAS号6943-65-3 乙撑双(异硫脲溴化铵) | CAS号107-06-2 1,2-二氯乙烷 | CAS号105-53-3 丙二酸二乙酯 | CAS号1066-54-2 三甲基硅基乙炔 | CAS号64-17-5 乙醇 | CAS号2225-23-2 乙烯二(硫代甲苯磺酸盐) | CAS号63512-47-0 2-[2-(carboxyme...

📜Ethylenebisisothiuronium Dihydrobromide置于sodium Hydroxide体系中,化学反应生成 1,2-双(羧甲硫基)-乙烷
参考文献:Us2657231
标题:Us2657231

专利信息

专利号:WO-2025038471-A1
优先权日:2023-08-11
标 题:Flow synthesis of organic adsorbents and a flow photo-reactor for the adsorption and degradation of contaminants in water sources
发明人：KHALIL SAFIYA; VERDUZCO RAFAEL; ALAZMI ABDULLAH
权利人:UNIV RICE WILLIAM M
摘要:A method of making a covalent organic framework includes continuously feeding a first precursor and a second precursor to a flow reactor; heating, and mixing the first and second precursors; nucleating and growing the covalent organic framework; and continuously outputting the covalent organic framework from the third section of the flow reactor. A photo-reactor for treating contaminated water includes: a light source; an enclosed channel around the light source; a cover comprising one or more lights illuminating the enclosed channel; and a covalent organic framework cased within the enclosed channel, where the covalent organic framework is photo-catalytically active for degrading a contaminant in the contaminated water so as to produce treated water. A method of treating contaminated water includes feeding the contaminated water to the photo-reactor and contacting the contaminated water with the covalent organic framework.

专利号:US-2009111737-A1
优先权日:1999-05-24
标题:Novel antibacterial agents
发明人：CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
权利人:CHRISTENSEN BURTON G; MORAN EDMUND J; GRIFFIN JOHN H; JUDICE J KEVIN; MU YONGQI; PACE JOHN L; MAMMEN MATHAI; AGGEN JAMES
摘要:This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands hasn a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, pencillinase enzyme, cephalosporinase enzyme, a transglycoslase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.

专利号:WO-9729091-A1
优先权日:1996-02-09
标题:Balanol analogues
发明人：NIELSEN JOHN; LYNGSOE LARS OLE
权利人:AUDA PHARMACEUTICALS APS; NIELSEN JOHN; LYNGSOE LARS OLE
摘要:The present invention relates to a solid phase methodology for the preparation of a combinatorial library of structural analogues of the natural product balanol (ophiocordin, azepinostatin), which is a protein kinase C (PKC) and protein kinase A (PKA) inhibitor. The method comprises solid-phase synthesis of the analog variants of balanol whereby a high molecular diversity is introduced. The synthetic scheme is based on a retrosynthetic analysis of the native structure which revealed three main building blocks suitable as templates for modification. The dicarboxy-functional moiety can be immobilised to the polymer support either as the monoallyl ester or as the internal anhydride. The libraries produced by the method are especially suited for high throughput screening of potential drug candidates for the treatment of mammals, especially humans.

专利号:US-7179794-B2
优先权日:1998-06-08
标题 :Multivalent macrolide antibiotics
发明人：GRIFFIN JOHN H; PACE JOHN L
权利人:THERAVANCE INC
摘要:Disclosed are multibinding compounds which include macrolide antibiotics, aminoglycosides, lincosamides, oxazolidinones, streptoramins, tetracycline and/or other compounds which bind to bacterial ribosomal RNA and/or to one or more proteins involved in ribosomal protein synthesis in the bacterium, which are useful in treating bacterial infections. The compounds adversely affect protein expression and have an antibacterial effect. The multibinding compounds of this invention containing from 2 to 10 ligands covalently attached to one or more linkers. Each ligand is macrolide antibiotic, aminoglycoside, lincosamide, oxazolidinone, streptogramin, tetracycline or other compound which binds to bacterial ribosomal RNA and/or one or more proteins involved in ribosomal protein synthesis in the bacterium.

专利号:WO-9710263-A1
优先权日:1995-09-12
标 题 :Actinomycin d analogues
发明人：TONG GLENN; NIELSEN JOHN
权利人:AUDA PHARMACEUTICALS APS; TONG GLENN; NIELSEN JOHN
摘要:The present invention relates to new compounds being structurally and functionally similar to Actinomycin D and to combinatorial libraries of such compounds. The Actinomycin D analogues according to the present invention comprise two linear or cyclic peptide moieties constituted by α-amino acids, β-amino acids and/or longer chain φ-amino acids, and a difunctional group which preferably is a cyclic entity, in particular, an aromatic or heteroaromatic entity acting as an intercalator group. Specific compounds and a library of such compounds may be prepared using conventional solid phase peptide synthesis (SPPS) methodologies. The novel compounds are expected to have affinity for DNA and RNA, and libraries thereof may therefore advantageously be used for screening purposes. Furthermore, a novel double-combinatorial technique that may be used in the preparation of librairies of broader classes of compounds has been developed.