CAS: 66092-62-4; 2-Bromo-5-Methyl-4-Nitropyridine

该化合物是卤代硝基丙烯衍生物,在有机合成和制药研究中具有重大效用,其溴和硝替代成分使其成为核生殖替代反应的多用途中间体,有助于构建复杂的异环框架.甲基组在提供额外功能化场地的同时,增强稳定性.该化合物因其反应性和结构特性,在农用化学品,药品和特殊材料的开发方面特别宝贵.高纯度确保交叉反应(如铃木或布沃德-哈特维格)的一致性能.由于对光和湿度的潜在敏感性,建议适当处理.

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合成工艺路线路线简述

    📜2-溴-5-甲基吡啶-4-胺 以37%的收率获得产物
    参考文献:Puszko,A.,Pr. Nauk. Ae Wroclawiu,1984,N 278,169-173
    标题:Puszko,A.,Pr. Nauk. Ae Wroclawiu,1984,N 278,169-173

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    专利信息


    专利号:US-11034690-B2
    优先权日:2016-11-11
    标 题:Heterocyclic modulators of lipid synthesis
    发明人:BUCKLEY DOUGLAS I; DUKE GREGORY; WAGMAN ALLAN S; EVANCHIK MARC; MCDOWELL ROBERT S
    权利人:SAGIMET BIOSCIENCES INC; SAGINIET BIOSCIENCES INC
    摘要:Compounds that are fatty acid synthesis modulators are provided. The compounds may be used to treat disorders characterized by disregulation of the fatty acid synthase function by modulating the function and/or the fatty acid synthase pathway. Methods are provided for treating such disorders including viral infections, such as hepatitis C infection, cancer and metabolic disorders, such as non-alcoholic steatohepatitis (NASH).

    专利号:US-2019308969-A1
    优先权日:2016-11-11
    标 题 :Heterocyclic modulators of lipid synthesis

    专利号:US-2012264737-A1
    优先权日:2011-03-08
    标题 :Heterocyclic Modulators of Lipid Synthesis

    专利号:JP-2023033259-A
    优先权日:2016-11-11
    标题:Heterocyclic modulators of lipid synthesis

    专利号:WO-2012122391-A1
    优先权日:2011-03-08
    标 题 :Heterocyclic modulators of lipid synthesis

    专利号:TW-201249796-A
    优先权日:2011-03-08
    标题:Heterocyclic modulators of lipid synthesis

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