CAS: 615-16-7; 2-Hydroxybenzimidazole

相似化合物

161468-45-7 615-16-7 5400-75-9

上下游产品

CAS号95-54-5 邻苯二胺(OPD) | CAS号201230-82-2 carbon monoxide | CAS号88-74-4 2-硝基苯胺 | CAS号57-13-6 尿素 | CAS号124-38-9 二氧化碳 | CAS号28144-70-9 Benzenecarboxim... | CAS号530-62-1 N,N'-羰基二咪唑(CDI) | CAS号118-92-3 邻氨基苯甲酸 | CAS号139487-04-0 5-iodo-1,3-dime... | CAS号5623-04-1 2-氨基-N-羟基苯甲酰胺 | CAS号5955-72-6 2-氯-6-硝基-1H-苯并[d]咪唑 | CAS号3705-86-0 5,6-dinitro-1,3... | CAS号143661-33-0 bis(1H-benzimid... | CAS号14394-91-3 1-(2-Hydroxy-1H... | CAS号93-84-5 5-硝基-2-苯并咪唑酮 | CAS号2033-29-6 5,6-二氯-1H-苯并[d]... | CAS号1848-99-3 3-羧基甲基-2-氧代-2,3... | CAS号2735-73-1 1,3-Diacetyl-1,... | CAS号27185-21-3 (1H-苯并咪唑-2-基)-苄胺

邻苯二胺置于potassium Carbonate,Lithium Bromide体系中,用 乙醇 作为反应溶剂,化学反应 1.0H,反应生成 2-羟基苯并咪唑
参考文献:Synthesis Of Benzimidazolones,Benzooxazolones,2-Amino-Benzothiazoles From Ethyl Cyanoformate And O-Phenylene Diamines,O-Aminophenols,Oaminothiophenols Promoted By Lithium Bromide
标题:Synthesis Of Benzimidazolones,Benzooxazolones,2-Amino-Benzothiazoles From Ethyl Cyanoformate And O-Phenylene Diamines,O-Aminophenols,Oaminothiophenols Promoted By Lithium Bromide
摘要:研究了溴化锂介导的1-氨基-2-杂芳基底物与氰基甲酸乙酯的缩合反应,以获得多样的烷基氨基甲酸酯保护的苯并杂氮卓酮.这一前所未有的反应可用于以非常好产率制备不同的氮卓酮,如2-苯并咪唑酮,2-苯并噁唑酮和2-氨基噻唑.
DOI:10.2174/157017811796064449

专利信息

专利号:WO-2021260722-A1
优先权日:2020-06-21
标 题:Design, synthesis of novel oxyindole inhibitors of denv rna dependent rna polymerase
发明人：GUNDLA RAMBABU; ASTHANA SHAILENDRA; BHATTACHARYYA SANKAR; MADDIPATI VENKATANARAYANA CHOWDARY; MITTAL LOVIKA; KAUR JASKARAN; RAWAT YOGITA
权利人:TRANSLATIONAL HEALTH SCIENCE AND TECH INSTITUTE; GANDHI INSTITUTE OF TECH AND MANAGEMENT
摘要:The present invention is drawn to novel compounds of formula I, II and III, including any conformational isomeric form, salts and solvates for inhibition of DENV RNA dependent and RNA polymerase. The present invention also discloses a process of synthesis of the compounds, compositions comprising the said compounds and use of the compounds and treatment comprising the compounds of the present invention.

专利号:US-11542269-B2
优先权日:2018-01-03
标 题:Prins reaction and compounds useful in the synthesis of halichondrin macrolides and analogs thereof
发明人：CHOI HYEONG-WOOK; FANG FRANCIS G
权利人:EISAI R&D MAN CO LTD
摘要:The invention provides methods utilizing Prins reaction in the preparation of compounds that may be useful as intermediates in the synthesis of halichondrin macrolides and analogs thereof. The invention also provides compounds that may be useful as intermediates in the synthesis of a halichondrin macrolides and methods for preparing the same.

专利号:US-10913749-B2
优先权日:2015-05-07
标 题 :Macrocyclization reactions and intermediates and other fragments useful in the synthesis of halichondrin macrolides
发明人：FANG FRANCIS G; KIM DAE-SHIK; CHOI HYEONG-WOOK; CHASE CHARLES E
权利人:EISAI R&D MAN CO LTD
摘要:The invention provides methods for the synthesis of a halichondrin macrolides through a macrocyclization strategy. The macrocyclization strategy of the present invention involves subjecting a non-macrocyclic intermediate to a carbon-carbon bond-forming reaction (e.g., an olefination reaction (e.g., Horner-Wadsworth-Emmons olefination), catalytic Ring-Closing Olefin Metathesis, or Nozaki-Hiyama-Kishi reaction) to afford a macrocyclic macrolide. The invention also provides compounds useful as intermediates in the synthesis of a halichondrin macrolides and methods for preparing the same.

专利号:US-11136335-B2
优先权日:2016-06-30
标题:Prins reaction and intermediates useful in the synthesis of halichondrin macrolides and analogs thereof
发明人：CHASE CHARLES E; CHOI HYEONG-WOOK; ENDO ATSUSHI; FANG FRANCIS G; KIM DAE-SHIK
权利人:EISAI R&D MAN CO LTD
摘要:The invention provides methods for the synthesis of a halichondrin macrolides or analogs thereof through a cyclization reaction strategy. The strategy of the present invention involves subjecting an intermediate to Prins reaction conditions to afford a macrolide. The invention also provides compounds useful as intermediates in the synthesis of a halichondrin macrolides or analogs thereof and methods for preparing the same.

专利号:US-5919969-A
优先权日:1996-06-05
标 题 :Synthesis of yellow couplers
发明人：CRAWLEY MICHAEL W
权利人:EASTMAN KODAK CO
摘要:The invention provides a method of synthesis of a image-dye forming coupler of formula (I) wherein X is a substituent linked to the coupler by an atom of oxygen, sulfur or nitrogen R1 is an alkyl or aryl group, R2 is a hydrogen atom or an alkyl group; R3 to R7 are the same or different and selected from a hydrogen atom and substituent groups; which method comprises the reaction of a compound of formula (II) wherein R and R1 are the same or different and are as defined above for R1 and X is as defined above with a compound of formula (III) wherein R2 to R7 are as defined above, in the presence of an inert organic solvent.

专利号:US-6710208-B2
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.