CAS: 40739-44-4; 1-(4-Butylphenyl)-2,2,2-Trifluoroethan-1-One

该化合物是一种含有分子式C12H13F3O的氟芳香酮.该化合物具有三氟乙酰组,附于丁基替代苯环,具有独特的电子和消毒特性,其三氟甲基组可增强脂性及代谢稳定性,使其在制药和农用化学研究中具有价值.丁基链为合成应用的结构改变提供了额外的灵活性.该氯酮是有机合成的多用途中间体,特别是在准备氟乙烯循环和生物活性分子方面.其定义明确的再活动性和稳定性在不同条件下使其适合于用于交叉相联反应,核分裂性添加以及需要受控氟化的其他变异.

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欧盟法规

ECHA物质C&L通报

上下游产品

1-butylbenzene

合成工艺路线路线简述

    📜丁苯,4-二甲氨基-1-三氟乙酰基吡啶三氟乙酸盐置于三氯化铝体系中,用 二氯甲烷 作为反应溶剂,化学反应 15.0H,以67%的收率获得产物碳酸盐离子载体 Iv
    参考文献:Eine Einfache Methode Zur Darstellung Von Aryl-Trifluormethylketonen
    标题:Eine Einfache Methode Zur Darstellung Von Aryl-Trifluormethylketonen
    摘要:制备芳基三氟甲基酮的简单方法.caret4-Dimethylamino-1-Trifluoroacetylpyrimidinium Trifluoroacetate (2) 是一种有效,易于处理且稳定的三氟乙酰化试剂.通过 2 与芳香族化合物 3 在氯化铝存在下的反应,可获得芳基三氟甲基酮 4,而且收率很高.
    DOI:10.1055/s-1996-4444

    海关参考信息

    专利信息


    专利号:US-12297327-B1
    优先权日:2022-05-09
    标 题:Polymer and preparation method therefor, and anion-exchange membrane
    发明人:ZHANG QIUGEN; MA YICHANG
    权利人:Tan Kah Kee Innovation Laboratory; XIAMEN KAH MEMBRANE TECH LTD
    摘要:The present disclosure relates to a polymer and a preparation method therefor, and an anion-exchange membrane. The polymer comprises a structural unit represented by Formula (1) and a structural unit represented by Formula (2), wherein Ar 1 and Ar 2 are each independently selected from an arylene group derived from an aromatic compound, L 1 is selected from a C1-C10 alkylene, R 2 is selected from a quaternary ammonium group, and R 4 is selected from H or a C1-C7 alkyl. A high-performance anion-exchange membrane having high ion conductivity, low swelling, and strong alkali resistance can be obtained from the polymer of the present application, and no noble metal catalyst is required in a synthesis method, which is environment-friendly and simple; the present application has a broad application prospect.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: O Dinten, Et Al. Lifetime Of Neutral-Carrier-Based Liquid Membranes In Aqueous Samples And Blood And The Lipophilicity Of Membrane Components. Anal Chem. 1991 Mar 15;63(6):596-603.

    合成参考文献


    参考文献:10.1007/bf00602093
    参考文献:10.1007/bf02262846
    摘要:Inglis JM, Ha T. Theoretical study of anion carriers based on trifluoroacetophenone. Structural Chemistry. 1997 Apr;8(2):109–19. doi: 10.1007/bf02262846.
    参考文献:10.1007/978-1-4613-4033-1_8
    摘要:Herman HB. Ion-Selective Electrodes. 1978. In: Environmental Pollutants. : Springer US; 1978.
    参考文献:10.1007/978-1-4615-4181-3_18
    摘要:Nam H, Cha GS. Alternative Polymer Matrices for Potentiometric Chemical Sensors. 2000. In: Biosensors and Their Applications. : Springer US; 2000.
    参考文献:10.1007/978-3-642-67803-5_9
    摘要:Schumacher E, Umland F. Neue Titrationen mit elektrochemischer Endpunktsanzeige. 1981. In: Analytiker-Taschenbuch. : Springer Berlin Heidelberg; 1981.
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