3-硫苯甲酸置于五氯化磷体系中,化学反应生成 3-氯磺酰基苯甲酸 参考文献:Robotic System For Underwater Inspection Of Bridge Piers 标题:Robotic System For Underwater Inspection Of Bridge Piers 摘要:研究目标是开发一种自动机器人系统,对桥梁下部结构进行安全,经济的水下检测.正在开发的系统概念是一种半自主机器人系统,可携带传感器平台在水下检测支撑柱的冲刷,老化或损坏情况.它向系统操作员提供位置数据和传感器信息(视频图像);在记录这些数据和信息的同时,还可以进行口头注释.操作员可发出基本命令并将其传送给水下设备.机载微处理器控制器自动完成详细控制.主要的水下设备由两个相同的移动机器人组成,它们通过电缆和绞盘系统相互连接,沿着码头的相对表面移动.每个机器人都有橡胶履带或带夹板的轮子,并由内部电机驱动.拉紧连接两个机器人的缆绳可提供牵引力.机器人可以垂直和水平移动.每个机器人操作自己的驱动电机和缆绳绞盘,通过机器人和控制台之间的反馈,自动协调运动和缆绳张紧.多个机器人围绕一个支撑柱均匀分布,可以检测较大的结构. DOI:10.1109/5289.863909
专利号:US-9303041-B2 优先权日:2012-08-21 标题 :Haptens of olanzapine 发明人:DONAHUE MATTHEW GARRETT; GONG YONG; SALTER RHYS; HRYHORENKO ERIC; DECORY THOMAS R; REMMERIE BART; SANKARAN BANUMATHI 权利人:JANSSEN PHARMACEUTICA NV; ORTHO CLINICAL DIAGNOSTICS INC 摘要:The invention relates to compounds of Formula I, wherein R 1 , R 2 , and R 3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from olanzapine. The invention also relates to conjugates of an olanzapine hapten and a protein.
专利号:US-5879894-A 优先权日:1993-03-19 标 题:Long emission wavelength chemiluminescent compounds and their use in test assays 发明人:LAW SAY-JONG; JIANG QINGPING; FISCHER WALTER; UNGER JOHN T; KRODEL ELIZABETH K; XI JUN 权利人:CHIRON DIAGNOSTICS CORP 摘要:An assay method incorporating at least two different chemiluminescent compounds for detection and/or quantitation of at least two substances in a test sample is described. The synthesis of chemiluminescent reagents or conjugates for use in such methods as well as kits incorporating such reagents are also disclosed. The assays have particular application in the field of clinical diagnostics.
专利号:EP-0617288-B1 优先权日:1993-03-19 标题 :Long emission wavelength chemiluminescent compounds and their use in test assays 发明人:LAW SAY-JONG; JIANG QINGPING; FISCHER WALTER; UNGER JOHN T; KRODEL ELIZABETH K 权利人:NOVARTIS AG; BAYER AG 摘要:An assay method incorporating at least two different chemiluminescent compounds for detection and/or quantitation of at least two substances in a test sample is described. The synthesis of chemiluminescent reagents or conjugates for use in such methods as well as kits incorporating such reagents are also disclosed. The assays have particular application in the field of clinical diagnostics.
专利号:WO-2009020967-A1 优先权日:2007-08-06 标 题:Activated esters for synthesis of sulfonated telechelic polycarbonates
专利号:US-9126942-B2 优先权日:2008-03-08 标题 :Arylsulfonyl pyrazoline carboxamidine derivatives as 5-HT6 antagonists 发明人:VAN LOEVEZIJN ARNOLD; IWEMA BAKKER WOUTER I; STOIT ALEX; RENSINK AGATHA M; VENHORST JENNIFER; VAN DER NEUT MARTINA A W; DE HAAN MARTIN; KRUSE CORNELIS G 权利人:ABBVIE BAHAMAS LTD 摘要:This invention concerns arylsulfonyl pyrazoline carboxamidine derivatives as antagonists of 5-ht6 receptors, to methods for the preparation of these compounds and to novel intermediates useful for their synthesis. The invention also relates to the uses of such compounds and compositions, particularly their use in administering them to patients to achieve a therapeutic effect in Parkinson's disease, Huntington's chorea, schizophrenia, anxiety, depression, manic depression, psychoses, epilepsy, obsessive compulsive disorders, mood disorders, migraine, Alzheimer's disease, age related cognitive decline, mild cognitive impairment, sleep disorders, eating disorders, anorexia, bulimia, binge eating disorders, panic attacks, akathisia, attention deficit hyperactivity disorder, attention deficit disorder, withdrawal from abuse of cocaine, ethanol, nicotine or benzodiazepines, pain, disorders associated with spinal trauma or head injury, hydrocephalus, functional bowel disorder, irritable bowel syndrome, obesity and type-2 diabetes. The compounds have the general formula (1) wherein the symbols have the meanings given in the description.
[参考文献]: Barry G Shearer, Et Al. Discovery Of A Novel Class Of Ppardelta Partial Agonists. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5018-22.
合成参考文献
摘要:Koutentis, P. A.; Ioannidou, H. A., Science of Synthesis Knowledge Updates, (2010) 1, 347. 摘要:Heydt, H., Science of Synthesis Knowledge Updates, (2014) 3, 412.