CAS: 35302-70-6; (E)-3-Hydroxy-5-Methoxystilbene
该化合物是天然化合物皮诺锡尔文的衍生物,以其强有力的生物活动著称;它具有很强的抗硫基特性,成为制药和农业应用中有价值的化合物;其单甲基醚形式增强了稳定性和溶性,便于各种制剂的处理和使用.
- 英文名称(E)-3-Hydroxy-5-Methoxystilbene
- 中文名称(E)-3-羟基-5-甲氧基二苯乙烯
- IUPAC名称(E)-3-methoxy-5-styrylphenol
- 其它别名Phenol, 3-Methoxy-5-(2-Phenylethenyl)-; Pinosylvin Mono Methyl Ether; Pinosylvin 3-(Methyl Ether); Pinosylvin, Methyl Ether; (E)-3-Hydroxy-5-Methoxystilbene; 5-M
- CAS编号35302-70-6
- MFCD编号:MFCD00210546
- EINECS号:694-600-5
- FDA UNII编号:KS4RJ46H5M
- 分子式:C15H14O2分子量:226.27
- 产品CID: 1360130
- 产品分类天然产物 → 酚类
- 相似结构搜索
- InChIKey: JVIXPWIEOVZVJC-BQYQJAHWSA-N
- JVIXPWIEOVZVJC-BQYQJAHWSA-N
- 计算化学: 氢键受体数2.0氢键供体数1.0可旋转键数3.0
物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS07 & GHS09;
注释: Exclamation mark & Environment - 危险类别急性毒性 类别4(经口)
严重眼刺激 类别2
水生慢性毒性 类别2
特定目标器官毒性 - 单次接触 类别3
皮肤腐蚀/刺激 类别2
严重眼刺激 类别2A - 警示词Warning(警告)
- 危险描述H302 |吞咽有害.
H319 |造成严重眼刺激.
H411 |对水生生物有毒并具有长期持续影响.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激. - 防范说明P302+P352-P305+P351+P338
- UN编号UN 3077 9 / PGIII
- 危险品标志Xn,N
- 安全声明26-61
- 危险类别码22-36-51/53
- WGK Germany3
欧盟法规
C&L通报上下游产品
CAS号21956-56-9 3,5-二甲氧基二苯乙烯 | CAS号7311-34-4 3.5-二甲氧基苯甲醛 | CAS号1080-32-6 苄基膦酸二乙酯 | CAS号100-39-0 溴化苄 | CAS号1449-46-3 苄基三苯基溴化膦 | CAS号133462-43-8 5-methoxy-2-(3-... | CAS号14531-52-3 二氢赤松素 | CAS号17635-59-5 二氢赤松素单甲醚 | CAS号22139-77-1 赤松素 | CAS号120467-08-5 4-(3,7-dimethyl... | CAS号78916-50-4 1,3-dimethoxy-5... | CAS号64125-60-6 Longistylin C合成工艺路线路线简述
- 合成目标产物 Pinosylvin Mono Methyl Ether 主要起始原料 Benzyltriphenylphosphonium Bromide
- (文献来源)合成步骤主要原料 Benzyltriphenylphosphonium Bromide
📜苯基膦酸二乙酯置于sodium Methylate,三溴化硼体系中,用 N,N-二甲基甲酰胺 用作溶剂,化学反应生成(E)-3-羟基-5-甲氧基二苯乙烯
参考文献:Synthesis And Inhibitory Effects Of Pinosylvin Derivatives On Prostaglandin E2 Production In Lipopolysaccharide-Induced Mouse Macrophage Cells
标题:Synthesis And Inhibitory Effects Of Pinosylvin Derivatives On Prostaglandin E2 Production In Lipopolysaccharide-Induced Mouse Macrophage Cells
摘要:A Series Of Natural Stilbenoids,Pinosylvin And Its Derivatives,Were Synthesized And Evaluated For The Inhibitory Activity Of Prostaglandin E,Production In Lipopolysaccharide-Induced Raw 264.7 Cells. Potential Inhibitors,Including 3,5-Dimethoxy-Trans-Stilbene And 3-Hydroxy-5-Benzyloxy-Trans-Stilbene,Have Been Newly Identified,And Thus Providing Chemical Leads For The Further Development Of Anti-Inflammatory Or Cancer Chemopreventive Agents. (C) 2004 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Bmcl.2004.09.022
海关参考信息
- 2901210000-乙烯
2902300000-甲苯
2902500000-苯乙烯
2905110000-甲醇 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
参考文献:10.1021/acs.jnatprod.7b00384
摘要:Eräsalo H, Hämäläinen M, Leppänen T, Mäki-Opas I, Laavola M, Haavikko R, Yli-Kauhaluoma J, Moilanen E. Natural Stilbenoids Have Anti-Inflammatory Properties in Vivo and Down-Regulate the Production of Inflammatory Mediators NO, IL6, and MCP1 Possibly in a PI3K/Akt-Dependent Manner. J Nat Prod. 2018 May 25;81(5):1131–42. doi: 10.1021/acs.jnatprod.7b00384.
📝 需求与反馈
尽可能描述清楚需求与问题信息
