CAS: 2926-27-4; Potassium Trifluoromethanesulfonate

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专利信息

专利号:WO-2024058665-A1
优先权日:2022-09-15
标 题:One-pot synthesis of 6-l-[18f] fluoro-3,4-dihydroxyphenylalanine (6-l-[18f] fdopa).
发明人：LUURTSEMA GEERT; KWIZERA CHANTAL; BLOK SIMON NIELS; FARINHA ANTUNES INES; ELSINGA PHILIPPUS HEIN; DE VRIES ERIK
权利人:UNIV GRONINGEN; ACADEMISCH ZIEKENHUIS GRONINGEN
摘要:The invention relates to the field of medicinal chemistry and radiopharmaceuticals, in particular to means, methods and cassettes for the automated synthesis of the radiotracer 6- L -[ 18 F]fluoro-3,4- dihydroxyphenylalanine (6- L -[ 18 F]FDOPA). Provided is a method for the one-pot synthesis of 6- L -[ 18 F]FDOPA comprising contacting a BOC- protected stannyl precursor of the formula I with [ 18 F] Tetraethylammonium fluoride ([ 18 F]Et 4 NF) in the presence of the Cu-catalyst Cu(Impy) 4 (OTf) 2 .

专利号:US-11059835-B2
优先权日:2014-08-15
标 题 :Synthesis of cephalosporin compounds
发明人：WALLER DAVID; GAZDA GREGORY; MINDEN ZACHARY; BARTON LISA; LEIGH CLIFTON
权利人:MERCK SHARP & DOHME
摘要:Provided herein is a method for the synthesis of cephalosporin antibiotic compounds comprising a palladium-catalyzed coupling reaction.

专利号:US-2016317682-A1
优先权日:2015-04-30
标题:PREPARATION OF Ag18F AND ITS USE IN THE SYNTHESIS OF PET RADIOTRACERS
发明人：SCOTT PETER J H; BROOKS ALLEN F; ICHIISHI NAOKO; SANFORD MELANIE S
权利人:UNIV MICHIGAN REGENTS; THE REGENTS OFTHE UNIV OF MICHIGAN
摘要:Copper-catalyzed radiofluorination of aryl iodides using Ag 18 F, methods of preparing Ag 18 F, and compounds obtained by copper-catalyzed radiofluorination of aryl iodides using Ag 18 F are disclosed. Diagnostic and therapeutic methods involving such compounds also are disclosed.

专利号:WO-2022238500-A1
优先权日:2021-05-12
标题 :Radiosynthesis of [18f] talazoparib
发明人：BOWDEN GREGORY DAVID; MAURER ANDREAS; STOTZ SOPHIE; KINZLER PAUL JOHANNES OSKAR MARIA; LAEMMERHOFER MICHAEL; ZENDER LARS; PICHLER BERND
权利人:UNIV TUEBINGEN MEDIZINISCHE FAKULTAET
摘要:The present invention relates to the synthesis of Poly (ADP ribose) polymerase (PARP) inhibitors and particularly to the radiosynthesis of PARP 1 inhibitors, more particularly to the synthesis of [18F] talazoparib.

专利号:US-7314962-B2
优先权日:2005-04-15
标题:Alkylation of aromatic compounds
发明人：HARMER MARK ANDREW; JUNK CHRISTOPHER P; MANZER LEO ERNEST
权利人:DU PONT
摘要:The present invention relates to the synthesis of alkylated aromatic compounds using ionic liquids as the solvent. Alkylated aromatic compounds are synthesized by reacting an aromatic compound with a monoolefin in the presence of an acid catalyst.

专利号:US-2007068343-A1
优先权日:2005-06-30
标 题:Synthesis of shape-specific transition metal nanoparticles
发明人：LUKEHART CHARLES M; MICHEL JASON A
权利人:LUKEHART CHARLES M; MICHEL JASON A
摘要:A method of producing colloidal, shaped nanoparticles of a transition metal or alloys thereof, comprising reducing ions of at least one transition metal in an aqueous solution thereof in the presence of at least one compound, which, at its isoelectric point, is a zwitterion and/or at least one small, non-polymeric anion and the nanoparticles produced thereby.