CAS: 14508-49-7; 2-Chloropyrazine

相似化合物

19745-07-4 4774-14-5 4858-85-9

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CAS号98-97-5 2-吡嗪羧酸 | CAS号6270-63-9 羟基吡嗪 | CAS号2423-65-6 吡嗪-N-氧化物 | CAS号290-37-9 吡嗪 | CAS号419581-32-1 CuBr(μ-2-chloro... | CAS号419581-33-2 CuI(μ-2-chlorop... | CAS号288-32-4 咪唑 | CAS号67-66-3 氯仿 | CAS号18156-74-6 三甲基硅咪唑(TSIM) | CAS号16025-16-4 Pyrazine, 2-chl... | CAS号111759-97-8 2-pyridin-2-ylp... | CAS号108030-81-5 2-(4-甲氧基苯基)吡嗪 | CAS号107697-83-6 2-phenylsulfany... | CAS号32111-21-0 2-碘吡嗪 | CAS号21279-62-9 3-氯吡嗪-2-酰胺 | CAS号36070-79-8 6-氯-2-吡嗪羧酰胺 | CAS号21279-64-1 5-氯吡嗪-2-甲酰胺 | CAS号4774-14-5 2,6-二氯吡嗪 | CAS号32111-28-7 2-甲氨基吡嗪 | CAS号3149-28-8 2-甲氧基吡嗪

2-甲酸吡嗪置于tetrakis(Acetonitrile)Copper(I)Tetrafluoroborate,1-Fluoro-2,4,6-Trimethylpyridin-1-Ium Tetrafluoroborate,Zinc(II) Chloride体系中,用 乙腈 用作溶剂,化学反应 12.0H,以48%的收率获得2-氯吡嗪
参考文献:(杂)芳基羧酸脱羧卤化的统一方法
标题:(杂)芳基羧酸脱羧卤化的统一方法
摘要:芳基卤化物是合成化学中的基本基序,在金属介导的交叉偶联反应中起着关键作用,并在药物发现中充当重要的支架.尽管芳基羧酸的热脱羧官能化已得到广泛探索,但现有的卤代脱羧方法的范围仍然有限,并且目前不存在提供从芳基羧酸前体获得任何类型的芳基卤化物的统一策略.在此,我们报告了一种通过配体到金属电荷转移对(杂)芳基羧酸进行直接脱羧卤化的通用催化方法.该策略适用于极其广泛的底物范围.我们利用芳基自由基中间体实现不同的功能化途径:(1) 原子转移以获取溴代或碘代(杂)芳烃或(2)自由基被铜捕获并随后还原消除以生成氯代或氟代(杂)芳烃.所提出的配体到金属的电荷转移机制得到了一系列光谱研究的支持.
Doi:10.1021/jacs.2C02392

专利信息

专利号:US-2023399302-A1
优先权日:2020-10-29
标题:Process for the preparation of heteroaryl-substituted sulfur(vi) compounds
发明人：LOPCHUK JUSTIN M; SHULTZ ZACHARY P; SCATTOLIN THOMAS
权利人:H LEE MOFFITT CANCER CT & RES
摘要:The present disclosure provides processes for the synthesis of organic compounds, in particular processes for the synthesis of heteroaryl-substituted sulfur(VI) compounds by nucleophilic aromatic substitution.

专利号:US-2012010409-A1
优先权日:2009-03-19
标题:Improved chemical synthesis of diazaindoles by chichibabin cyclization
发明人：LEE GEORGE E; SHRIMP II FREDERICK L; WEIBERTH FRANZ J
权利人:LEE GEORGE E; SHRIMP II FREDERICK L; WEIBERTH FRANZ J; SANOFI SA
摘要:An improved synthesis method for making diazaindoles using a Chichibabin cyclization is disclosed. In particular, this method is useful for making the compound of Formula I.

专利号:US-2025034146-A1
优先权日:2023-07-13
标题:Electro-photochemical synthesis of 1,2,4-triazolo-[4,3-a]pyrazine
发明人：PIERCEY DAVIN GLENN; YOUNT JOSEPH ROBERT
权利人:PURDUE RESEARCH FOUNDATION
摘要:A method of preparing a 1,2,4-triazolo-[4,3-a]pyrazine backbone using an electro-photochemical process comprising coupling a compound comprising a 5-substituted tetrazole moiety to a compound comprising an optionally substituted pyrazine moiety electrochemically and subjecting the resulting compound to photochemical excitation with ultraviolet light.

专利号:WO-2013112823-A1
优先权日:2012-01-25
标题 :Heterophase synthesis of metal-coordinated framework materials for particle size control
发明人：AHN DONGCHAN; LEE JEONG YONG
权利人:DOW CORNING
摘要:Various embodiments of the present invention relate to a method of preparing coordination polymer crystals, and to the crystals produced thereby. The method includes providing a composition. The composition includes Component (i), a metal-containing compound that is a source of one or more metal ions; Component (ii), a bridging ligand-containing compound that is a source of one or more bridging ligands; Component (iii), a first liquid in which (i) and (ii) are soluble; and Component (iv), a second liquid immiscible with the first liquid. The method includes mixing the composition to form an emulsion. The method also includes maintaining the emulsion for a time sufficient to produce a crystalline coordination polymer. Various embodiments also provide methods of making membranes and membranes made thereby wherein the membrane-forming composition includes the coordination polymer crystals, including methods of making membranes wherein coordination polymer crystals form in the membrane or in the membrane-forming composition before, during, or after curing of the membrane-forming composition. Various embodiments also provide methods of gas separation using the membranes.

专利号:CN-1189462-C
优先权日:2002-09-24
标题:Catalyst and synthesis method used in the synthesis of 2-cyanopyrazine from 2-methylpyrazine

专利号:CN-1408711-A
优先权日:2002-09-24
标 题 :Catalyst and synthesis method used in the synthesis of 2-cyanopyrazine from 2-methylpyrazine