CAS: 128-09-6; 1-Chloropyrrolidine-2,5-Dione

相似化合物

123-56-8 1121-07-9 132178-37-1

上下游产品

CAS号123-56-8 丁二酰亚胺 | CAS号3355-28-0 1-溴-2-丁炔 | CAS号507-40-4 次氨酸叔丁基酯 | CAS号5775-33-7 N-chloro-N-ethy... | CAS号5775-34-8 N-chloro-N-prop... | CAS号64-19-7 冰醋酸 | CAS号35570-68-4 6-氯恶唑并[4,5-b]吡啶... | CAS号38185-55-6 2-氨基-3-氯-5-溴吡啶 | CAS号538-37-4 二苄基磷酰基氯 | CAS号108-94-1 环己酮 | CAS号14204-24-1 1-苯硫基-吡咯啉-2,5-二酮 | CAS号123-56-8 丁二酰亚胺 | CAS号41212-96-8 1-(2-氯乙基)吡咯烷-2,5-二酮 | CAS号39204-47-2 2-氯甲基吡嗪 | CAS号4812-45-7 3-氯-5-硝基-1H-吲唑 | CAS号516-12-1 N-碘代丁二酰亚胺

丁二酰亚胺置于氯体系中,化学反应生成N-氯代丁二酰亚胺
参考文献:Betulin和diacetylbetulin中的氢亲电取代
标题:Betulin和diacetylbetulin中的氢亲电取代
摘要:可以被视为空间受阻的烯烃的桦木素和二乙酰基白蛋白与n-氯-,N-溴-和n-碘代琥珀酰亚胺反应,以定量的总收率得到烯丙基和乙烯基取代的产物.在cl
Doi:10.1134/s107042801801013X

专利信息

专利号:US-7301006-B2
优先权日:2002-07-16
标 题 :Methods and materials for the synthesis of modified peptides
发明人：YOUNG TRAVIS G; KIESSLING LAURA L
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Methods and protected amino acids useful as building blocks (protected monomers) for the synthesis of peptides and proteins that are selectively modified at one or more side-chain hydroxyl groups. Azide-bearing protecting groups allow the selective deprotection of side-chain hydroxyl groups of amino acids after synthesis of a peptide. Reaction conditions for removal of the azide-bearing protecting group can be selected which are substantially orthogonal to those that will remove α-amino protecting groups typically employed in peptide synthesis, such that hydroxyl groups protected with the azide-bearing protecting group remain protected during synthesis of the peptide chain. Various protecting groups which are readily available can be used for protecting potentially reactive side chain groups of amino acids in the peptide or protein to be modified. Preferred side-chain protecting groups are chemically distinguishable from the azide-bearing protecting group and substantially orthogonal reaction conditions can be selected such that side-chain protection of other amino acids is maintained when the azide-bearing protecting group is removed. The use of the azide-bearing protecting group of this invention for one or more hydroxy amino acids during peptide synthesis allows the selective unmasking of those azide-protected side-chain hydroxyl groups and selective modification of the hydroxyl groups that are selectively unmasked. The methods and materials herein are particularly used in synthesis of sulfated, phosphorylated and glycosylated peptides and proteins. Kits and methods of synthesizing a modified peptide or protein using the kits are also provided.

专利号:US-7939679-B2
优先权日:2006-01-19
标题:Method for synthesis of ciguatoxin CTX1B and compounds useful for the synthesis of ciguatoxin CTX1B
发明人：HIRAMA MASAHIRO; INOUE MASAYUKI
权利人:JAPAN SCIENCE & TECH AGENCY
摘要:Disclosed is a method for total synthesis of CTX1B, which is developed for the synthesis of a ciguatoxin analogue such as CTX3C and enables the more efficient application of an established reaction to the total synthesis of CTC1B. More specifically, disclosed is a method for total synthesis of CTX1B comprising; an O.S-acetal formation for synthesizing a novel compound (3); a radical cyclization reaction for constructing a 9-membered ring formation reaction including a novel compound (6) through a novel compound (8) and yielding a compound (D); and a deprotection for yielding CTX1B. Also disclosed are novel compounds (1) to (8) which are particularly useful for synthesis of CTX1B and can be used for the synthesis of a ciguatoxin analogue.

专利号:US-8822702-B2
优先权日:2002-12-20
标 题 :Synthesis of amines and intermediates for the synthesis thereof
发明人：BERENS ULRICH; DOSENBACH OLIVER; SPRENGER DANIEL
权利人:BERENS ULRICH; DOSENBACH OLIVER; SPRENGER DANIEL; BASF SE
摘要:The invention relates in a first embodiment to a method for the manufacture of esters of the formula I, n nor especially of amides of the formula II,n n nwherein the symbols have the meanings given in the specification, as well as other intermediates and compounds useful in the synthesis of tryptamines and other substances mentioned in the title. The synthesis methods and intermediates are useful in the synthesis of pharmaceuticals.

专利号:US-2007287843-A1
优先权日:2004-04-07
标题 :Methods and Intermediates for the Synthesis of Delta-9 Tetrahydrocannabinol
发明人：CABAJ JOHN E; PARIZA RICHARD J; LUKESH JULIE M
权利人:CABAJ JOHN E; PARIZA RICHARD J; LUKESH JULIE M
摘要:Processes are disclosed for the synthesis of Delta-9 tetrahydrocannabinol which result in an improved Y-THC/Y-THC ratio, and intermediates are disclosed that may be used in the synthesis of Delta-9 tetrahydrocannabinol such that improved Y-THCIY-THC ratios are achieved. The intermediates may be cyclic compounds prepared from 2-Carene. There is also provided a scaleable process for the preparation of (+)-p-menth-2-ene-1,8-diol, another intermediate used in the synthesis of delta-9-tetrahydrocannibinol.

专利号:US-6552213-B1
优先权日:2002-05-10
标 题:Stereoselective route to produce tris-O-substituted-(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene, an intermediate in the synthesis of trans-resveratrol
发明人：DESHPANDE PANDURANG BALWANT; SENTHILKUMAR UDAYAMPALAYAM PAL; ANDREW GNANAPRAKASAM
权利人:ORCHID CHEMICALS & PHARM LTD
摘要:The present invention relates to a new stereoselective method for the preparation of tris-O-substituted-(E)-1-(3,5-dihydroxyphenyl)-2-(4-hydroxyphenyl)ethene derivative of the formula (I) which is a key intermediate in the synthesis of trans-resveratrol (I, R2=R2=R3=H). The invention also provides a method for the exclusive synthesis of trans-isomer of compounds of formula (I) without any contamination of cis-isomer.

专利号:US-2024287126-A1
优先权日:2021-05-14
标 题:Novel synthesis of cholesterol
发明人：SCHINZER DIETER; SPIESS OLIVER; MUNT MAXIM; INDOLESE ADRIANO; ROUX LIONEL
权利人:CORDENPHARMA INT GMBH; UNIV OTTO VON GUERICKE MAGDEBURG; CORDENPHARMA INT
摘要:The invention relates to a synthesis of cholesterol; a ring opening step of the compound of formula (I) and subsequent activation and reduction step yielding cholesterol. The inventions relates also to intermediates achieved during said synthesis.